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PNU-176798 is an agent with antimicrobial.
PNU-176798 is an agent with antimicrobial.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | PNU-176798 is an agent with antimicrobial. |
体外活性 | PNU-176798 is an agent of antimicrobial, with a minimum inhibitory concentration (MIC) of 1.4 μM for E. coli.PNU-176798 blocks translation, 70S initiation with IC50s of 0.53, and 32 μM, respectively. PNU-176798 inhibits fMet-tRNA binding to the 70S ribosomes, with an IC50 of 32 μM. PNU-176798 inhibits peptidyl transferase (IC50, 40 μM), and the inhibition is more pronounced in the presence of elongation factor P (EF-P). PNU-176798 markedly inhibits the EF-G-mediated translocation of fMet-tRNA (IC50, 8 μM)[1]. |
分子量 | 360.36 |
分子式 | C16H13FN4O3S |
CAS No. | 428861-91-0 |
密度 | 1.49 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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