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Tocainide hydrochloride 是一种sodium channel 阻滞剂,它阻断神经膜中产生疼痛的病灶中的钠通道。Tocainide hydrochloride 是利多卡因 (lignocaine) 的一种伯胺类似物,可有效抑制各种情况下的室性心律失常。
Tocainide hydrochloride 是一种sodium channel 阻滞剂,它阻断神经膜中产生疼痛的病灶中的钠通道。Tocainide hydrochloride 是利多卡因 (lignocaine) 的一种伯胺类似物,可有效抑制各种情况下的室性心律失常。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 542 | 5日内发货 | |
5 mg | ¥ 913 | 5日内发货 | |
10 mg | ¥ 1,710 | 5日内发货 | |
1 mL x 10 mM (in DMSO) | ¥ 983 | 5日内发货 |
产品描述 | Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1] [2]. |
靶点活性 | Na+ channel: |
体内活性 | Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models causes the prompt return of ventricular ectopic activity [1]. |
分子量 | 228.718 |
分子式 | C11H17ClN2O |
CAS No. | 71395-14-7 |
密度 | 1.31g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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