Sofiniclin

Name: Sofiniclin
Brand: TargetMol
SKU: T10226
Price: 347 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T10226Cas号 799279-80-4

别名 ABT 894

Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).

Sofiniclin

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产品编号 T10226 别名 ABT 894Cas号 799279-80-4

Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).

规格	价格	库存
25 mg	¥ 11,700	6-8周
50 mg	¥ 15,300	6-8周
100 mg	¥ 19,500	6-8周

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产品介绍

生物活性

产品描述	Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).
体外活性	Sofiniclin is more potent than ABT-089 at both receptor subtypes, with Ki values of 1.3 nM for 125I-epibatidine binding and of 1.9 nM for 125I-α-conotoxinMII binding [1].
体内活性	Compared to vehicle monkey, Sofiniclin (0.001 to 0.10 mg/kg, p.o.) produces significant reductions in LIDs [1]. Sofiniclin (0.1 mg/kg) does not decrease LIDs in monkeys with severe nigrostriatal damage [2].
别名	ABT 894