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Quinacrine mustard hydrochloride 是一种荧光染料,也 是一种多环芳香剂,可作为诱变剂诱导细菌的突变体。Quinacrine mustard hydrochloride 能选择性地与腺嘌呤-胸腺嘧啶(AT)碱基对结合,而不 是与鸟嘌呤-胞嘧啶(GC)碱基对结合,诱导细胞周期停滞在 G2/M 期。Quinacrine mustard (hydrochloride) 已被用于标记移相染色体,以通过自动放射摄影技术进行核型分析。
Quinacrine mustard hydrochloride 是一种荧光染料,也 是一种多环芳香剂,可作为诱变剂诱导细菌的突变体。Quinacrine mustard hydrochloride 能选择性地与腺嘌呤-胸腺嘧啶(AT)碱基对结合,而不 是与鸟嘌呤-胞嘧啶(GC)碱基对结合,诱导细胞周期停滞在 G2/M 期。Quinacrine mustard (hydrochloride) 已被用于标记移相染色体,以通过自动放射摄影技术进行核型分析。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 1,198 | 35日内发货 | |
10 mg | ¥ 1,998 | 35日内发货 | |
25 mg | ¥ 4,450 | 35日内发货 | |
50 mg | ¥ 8,240 | 35日内发货 |
产品描述 | Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography. |
体外活性 | Quinacrine mustard hydrochloride (0.2 μM; 4h) 在HL-60细胞中诱导细胞周期在G2+M期暂停,并使得该阶段细胞累积增加了50%。[1] Quinacrine mustard hydrochloride (5 μg/ml) 可用于植物、动物或人类染色体的DNA染色。[2] Quinacrine mustard hydrochloride (28 μM) 增加了暴露于细菌后出现的突变体数量。[3] |
别名 | 奎纳克林芥末盐酸盐, Quinacrine mustard HCl |
分子量 | 505.31 |
分子式 | C23H29Cl4N3O |
CAS No. | 4213-45-0 |
存储 | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | Chloroform: Soluble H2O: Soluble |
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