PAD2-IN-1

Name: PAD2-IN-1
Brand: TargetMol
SKU: T39515
Rating: 4.5 (1 reviews)

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产品编号 T39515Cas号 2095109-82-1

别名 PAD2-IN-1

PAD2-IN-1, a benzimidazole-based derivative, is an efficacious and specific inhibitor of protein arginine deiminase 2 (PAD2). Demonstrating remarkable selectivity, PAD2-IN-1 exhibits a 95-fold higher affinity for PAD2 in comparison to PAD4 and a 79-fold higher affinity than PAD3.

PAD2-IN-1

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产品编号 T39515 别名 PAD2-IN-1Cas号 2095109-82-1

规格	价格	库存	数量
25 mg	¥ 12,800	6-8周

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产品描述	PAD2-IN-1, a benzimidazole-based derivative, is an efficacious and specific inhibitor of protein arginine deiminase 2 (PAD2). Demonstrating remarkable selectivity, PAD2-IN-1 exhibits a 95-fold higher affinity for PAD2 in comparison to PAD4 and a 79-fold higher affinity than PAD3.
体外活性	In the target engagement assay, the EC 50 of PAD2-IN-1 (compound 32a) is 8.3 μM in HEK293T/PAD2 cells, the enhanced potency of PAD2-IN-1 overcomes its relatively poor ability to enter cells[1]. PAD2-IN-1 (compound 32a; 1-25 μM) treatment strongly inhibits histone H3 citrullination with an EC 50 of 2.7 μM in HEK293T/PAD2 cells[1].
别名	PAD2-IN-1