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NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC₅₀ of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1β release in a mouse model of acute peritonitis [1].
NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC₅₀ of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1β release in a mouse model of acute peritonitis [1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC₅₀ of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1β release in a mouse model of acute peritonitis [1]. |
靶点活性 | NLRP3:214 nM |
分子量 | 437.94 |
分子式 | C19H24ClN5O3S |
CAS No. | 2409825-32-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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