NB-598 Maleate

Name: NB-598 Maleate
Brand: TargetMol
SKU: T12199
Price: 538 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T12199Cas号 155294-62-5

NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.

NB-598 Maleate

还可以

产品编号 T12199Cas号 155294-62-5

NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.

规格	价格	库存
2 mg	¥ 1,250	5日内发货
5 mg	¥ 2,160	5日内发货
25 mg	¥ 6,290	1-2周
50 mg	¥ 8,170	1-2周
100 mg	¥ 13,300	1-2周

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产品介绍

生物活性

产品描述

NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.

体外活性

NB-598, an inhibitor of squalene epoxidase, on cholesterol absorption from the intestinal epithelia.?NB-598 (10 microM) inhibited the synthesis of sterol and sterol ester from [14C]acetate without affecting the synthesis of other lipids such as phospholipids (PL), free fatty acids (FFA) and triacylglycerol (TG).?When labeled lipid was apically loaded as a micellar lipid solution into Caco-2 cell cultures, NB-598 reduced basolaterally secreted radioactivity in cholesterol, cholesterol ester, PL and TG[1].

化学信息

分子量	565.74
分子式	C₃₁H₃₅NO₅S₂
CAS No.	155294-62-5
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (176.76 mM), Sonication is recommended.

溶液配制表

	1mg	5mg	10mg	50mg
1 mM	1.7676 mL	8.8380 mL	17.6760 mL	88.3798 mL
5 mM	0.3535 mL	1.7676 mL	3.5352 mL	17.6760 mL
10 mM	0.1768 mL	0.8838 mL	1.7676 mL	8.8380 mL
20 mM	0.0884 mL	0.4419 mL	0.8838 mL	4.4190 mL
50 mM	0.0354 mL	0.1768 mL	0.3535 mL	1.7676 mL
100 mM	0.0177 mL	0.0884 mL	0.1768 mL	0.8838 mL