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N-Carbethoxy-4-piperidone

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产品编号 T1340Cas号 29976-53-2
别名 N-乙氧羰基-4-哌啶酮

N-Carbethoxy-4-piperidone 是一种aminopyrimidine 衍生物,含有它们的组合物被用作药物。

N-Carbethoxy-4-piperidone

N-Carbethoxy-4-piperidone

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纯度: 97.82%
产品编号 T1340 别名 N-乙氧羰基-4-哌啶酮Cas号 29976-53-2

N-Carbethoxy-4-piperidone 是一种aminopyrimidine 衍生物,含有它们的组合物被用作药物。

规格价格库存数量
1 g
¥ 99
现货
1 mL x 10 mM (in DMSO)
¥ 117
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产品介绍

生物活性
产品描述
N-Carbethoxy-4-piperidone is an aminopyrimidine derivative, compositions containing them and there served as pharmaceuticals.
激酶实验
A crude cell-free extract is isolated from LI 210 cells in culture by suspension of the cells in a given volume of 0.05mol/LTris-HCl buffer, pH 7.4, and sonic extraction with a Biosonik at 70% maximal output for 30 sec. The supernatant is collected after centrifugation at 105,000 × g for 60 min (4°C) in a Model L Spinco ultracentrifuge. The final protein concentration of the cell-free extracts is approximately 3 mg/mL. The extracts are used as the source of enzymes. Ribonucleotide reductase activity is measured. A unit of enzyme is defined as the amount that catalyzed dCMP synthesis at a rate of 1 mμmole/hr. The assay systems for the measurement of pyrimidine nucleoside (CR) and deoxynucleoside (TdR, CdR) kinases are essentially those described by Chu and Fischer. However, reactions are terminated by heating for 2 min in a boiling water bath, and the phosphorylated derivatives are isolated according to the method of Bach. Fifty-jul aliquots are applied to 1-inch discs of diethylaminoethyl paper, which are then placed in counting vials and eluted with 0.5 mL of 0.5 mol/LPCA. After 1 hr, 12 mL of Diotol are added, and the radioactivity is determined.
别名N-乙氧羰基-4-哌啶酮
化学信息
分子量171.19
分子式C8H13NO3
CAS No.29976-53-2
SmilesCCOC(=O)N1CCC(=O)CC1
密度1.135g/mLat 25°C(lit.)
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度信息
DMSO: 60 mg/mL (350.49 mM), Sonication is recommended.
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM5.8415 mL29.2073 mL58.4146 mL292.0731 mL
5 mM1.1683 mL5.8415 mL11.6829 mL58.4146 mL
10 mM0.5841 mL2.9207 mL5.8415 mL29.2073 mL
20 mM0.2921 mL1.4604 mL2.9207 mL14.6037 mL
50 mM0.1168 mL0.5841 mL1.1683 mL5.8415 mL
100 mM0.0584 mL0.2921 mL0.5841 mL2.9207 mL

SCI 文献

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ,每只动物体重 20 g ,给药体积 100 μLTargetMol | Animal experiments 一共给药动物 10 只 ,您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60% ddH2O. 那么您的工作液浓度为 2 mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween 80, 混匀澄清,再加 600μLddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
%Tween 80
%ddH2O

剂量转换

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