LY223982

Name: LY223982
Brand: TargetMol
SKU: T15803
Rating: 4.5 (1 reviews)

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产品编号 T15803Cas号 117423-74-2

别名 SKF107324, CGS23131

LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.

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LY223982

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产品编号 T15803 别名 SKF107324, CGS23131Cas号 117423-74-2

LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.

规格	价格	库存
2 mg	¥ 591	5日内发货
5 mg	¥ 997	5日内发货
25 mg	¥ 4,150	8-10周
50 mg	¥ 5,400	8-10周
100 mg	¥ 9,150	8-10周

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产品介绍

生物活性

产品描述	LY223982 is an effective and specific inhibitor of the leukotriene B4 receptor (IC50: 13.2 nM). It also can against [3H]LTB4 binding to LTB4 receptor.
靶点活性	LTB4:13.2 nM
体外活性	LY223982 is also an effective antagonist of the aggregation of human neutrophils by LTB4 (IC50, 100 nM).
体内活性	LY223982 suppresses transient leukopenia induced in rabbits with LTB4 (ED50, 3 mg/kg) but not with FMLP. It shows no agonist activity in any of the test systems.
别名	SKF107324, CGS23131

化学信息

分子量	502.55
分子式	C₃₀H₃₀O₇
CAS No.	117423-74-2
密度	1.235 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (198.98 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9899 mL	9.9493 mL	19.8985 mL	99.4926 mL
5 mM	0.3980 mL	1.9899 mL	3.9797 mL	19.8985 mL
10 mM	0.1990 mL	0.9949 mL	1.9899 mL	9.9493 mL
20 mM	0.0995 mL	0.4975 mL	0.9949 mL	4.9746 mL
50 mM	0.0398 mL	0.1990 mL	0.3980 mL	1.9899 mL
100 mM	0.0199 mL	0.0995 mL	0.1990 mL	0.9949 mL