GNE-502

Name: GNE-502
Brand: TargetMol
SKU: T39369
Price: 953 USD
Availability: InStock
Rating: 4.5 (1 reviews)

还可以

产品编号 T39369Cas号 1953134-16-1

GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.

GNE-502

还可以

产品编号 T39369Cas号 1953134-16-1

GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.

规格	价格	库存	数量
5 mg	¥ 6,250	期货

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产品介绍

生物活性

产品描述

GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.

体内活性

GNE-502 (10 and 100 mg/kg; p.o.) possesses sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model[1]. ..

GNE-502 shows dose dependent tumor growth inhibition at 10 mg/kg and 30 mg/kg, with tumor stasis at 100 mg/kg[1]. Animal Model: Mouse[1]Dosage: 10 and 100 mg/kg (Pharmacokinetic Analysis) Administration: P.o. Result: Possessed sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.