BI-2545

Name: BI-2545
Brand: TargetMol
SKU: T14560
Rating: 4.5 (1 reviews)

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产品编号 T14560Cas号 2162961-71-7

BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.

BI-2545

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产品编号 T14560Cas号 2162961-71-7

BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.

规格	价格	库存
2 mg	¥ 468	5日内发货
25 mg	¥ 4,310	6-8周
50 mg	¥ 5,610	6-8周
100 mg	¥ 9,570	6-8周

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产品描述	BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.
靶点活性	ATX (human):3.4 nM, C50: 2.2 nM, ATX (rat):
体外活性	BI-2545 displays good potency in the LPA and rat whole blood assay with IC50s of 29 nM and 96 nM, respectively[1].
体内活性	BI-2545 (10 mg/kg; p.o.) has high and sustained in vivo efficacy in reducing LPAs[1] and it also has a half-life of t1/2=3.4 hours[1].