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AT7519 is a kinase inhibitor (IC50: 0.19, 0.044, 0.51, 0.067, 0.66 and 0.018 μM for CDK1/cyclinB, CDK2/CyclinA, CDK2/Cyclin E, CDk4/CyclinD1, CDK6/Cyclin D3, CDk5/p35).
AT7519 is a kinase inhibitor (IC50: 0.19, 0.044, 0.51, 0.067, 0.66 and 0.018 μM for CDK1/cyclinB, CDK2/CyclinA, CDK2/Cyclin E, CDk4/CyclinD1, CDK6/Cyclin D3, CDk5/p35).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 413 | 5日内发货 | |
5 mg | ¥ 672 | 1-2周 | |
10 mg | ¥ 1,280 | 1-2周 | |
100 mg | ¥ 5,740 | 1-2周 |
产品描述 | AT7519 is a kinase inhibitor (IC50: 0.19, 0.044, 0.51, 0.067, 0.66 and 0.018 μM for CDK1/cyclinB, CDK2/CyclinA, CDK2/Cyclin E, CDk4/CyclinD1, CDK6/Cyclin D3, CDk5/p35). |
靶点活性 | CDK4-CyclinD1:100 nM (IC50), CDK5-p35:13 nM (IC50), CDK6-CyclinD3:170 nM (IC50), CDK2-CyclinA:47 nM (IC50), CDK1-CyclinB:210 nM (IC50), CDK9-CyclinT:10 nM (IC50), CDK7-CyclinH-MAT1:2400 nM (IC50), GSK-3β:89 nM (IC50) |
别名 | AT7519 trifluoroacetate |
分子量 | 496.27 |
分子式 | C18H18Cl2F3N5O4 |
CAS No. | 1431697-85-6 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMSO: Soluble |
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