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Anti-MICB Monoclonal Antibody-AF488

产品编号 TMAZ-0189A4
别名 MHC class I polypeptide-related sequence B

Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.

Anti-MICB Monoclonal Antibody-AF488

Anti-MICB Monoclonal Antibody-AF488

纯度: 无数据
产品编号 TMAZ-0189A4 别名 MHC class I polypeptide-related sequence B

Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 1,760.3¥ 3,0357日内发货
50 μg¥ 2,933.64¥ 5,0587日内发货
100 μg¥ 4,400.46¥ 7,5877日内发货
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产品介绍

生物活性
产品描述
Anti-MICB Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
别名MHC class I polypeptide-related sequence B
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of MICB overexpressed 326F cells with TMAZ-0189A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MICB protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed: 11777960, PubMed: 11491531). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production
偶联与修饰
偶联
AF488
其他可选修饰符
Biotin/APC/PE/AF555/AF647
可提供抗体种类
2
抗原信息
免疫原
MICB
抗原种属
Human
基因ID
4277
Uniprot ID
研究领域
Drug Target
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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