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Cediranib maleate
产品编号 T2500LCas号 857036-77-2
别名 AZD-2171, 西地尼布马来酸盐, Recentin, AZD2171, AZD2171 maleate, AZD 2171
Cediranib is a potent and selective inhibitor of VEGF with antineoplastic activities. It inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.
Cediranib maleate
产品编号 T2500L 别名 AZD-2171, 西地尼布马来酸盐, Recentin, AZD2171, AZD2171 maleate, AZD 2171Cas号 857036-77-2
Cediranib is a potent and selective inhibitor of VEGF with antineoplastic activities. It inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 252 | 5日内发货 | |
| 5 mg | ¥ 413 | 5日内发货 | |
| 10 mg | ¥ 715 | 5日内发货 | |
| 1 mL x 10 mM (in DMSO) | ¥ 516 | 5日内发货 |
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产品介绍
生物活性
化学信息
| 产品描述 | Cediranib is a potent and selective inhibitor of VEGF with antineoplastic activities. It inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth. |
| 靶点活性 | KDR:1 nM (IC50), c-Kit:2 nM (IC50), FLK1:5 nM (IC50), FLT4:3 nM (IC50), PDGFRα:36 nM (IC50), PDGFRβ:5 nM (IC50) |
| 别名 | AZD-2171, 西地尼布马来酸盐, Recentin, AZD2171, AZD2171 maleate, AZD 2171 |
| 分子量 | 566.58 |
| 分子式 | C29H31FN4O7 |
| CAS No. | 857036-77-2 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | DMSO: Soluble |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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