8-Azakinetin riboside, a structural analog of kinetin riboside, exhibits cytotoxic activity [1].

Azakinetin riboside (compound 7) demonstrates cytotoxic activity against HeLaWT, MCF7, Caco-2, OVCAR-3, MIAPaCa-2, and MRC-5 cells at concentrations ranging from 0-100 µM over 24, 48, and 72 hours. The IC50 values are more than 100, 27, 25, more than 100, more than 100, 100 µM at 24 hours; 14.5, 4.3, 18.7, 76, 2.8, 11.7 µM at 48 hours; and 4.6, 3.8, 11.5, 1.1, 1.1, 4.6 µM at 72 hours, respectively.