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β-Secretase Inhibitor IV
还可以产品编号 T13434Cas号 797035-11-1
β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).
β-Secretase Inhibitor IV
还可以产品编号 T13434Cas号 797035-11-1
β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 500 μg | ¥ 2,340 | 35日内发货 | |
| 1 mg | ¥ 4,420 | 35日内发货 | |
| 5 mg | ¥ 17,300 | 35日内发货 |
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| 产品描述 | β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively). |
| 靶点活性 | BACE1:15.3±0.6 nM , BACE2:230±26 nM , Cathepsin D:7620±210 nM |
| 体外活性 | β-Secretase Inhibitor IV (Compound 2) inhibits the production of Aβ peptides with an EC50 of 43 nM in the cell culture assay. β-Secretase Inhibitor IV potently suppresses the secretion of sAPP_NF and EV40 from HEK293T cells(IC50 : 30 nM). |
| 分子量 | 578.72 |
| 分子式 | C31H38N4O5S |
| CAS No. | 797035-11-1 |
| 密度 | 1.30 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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