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规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 692 | 5日内发货 | |
5 mg | ¥ 1,280 | 5日内发货 |
产品描述 | (R)-(+)-Dimethindene maleate is an orally active H 1 -receptor blocker. |
体外活性 | (R)-(+)-Dimethindene maleate possesses membrane-stabilising effect [1]. |
体内活性 | (R)-(+)-Dimethindene maleate (10 mL/kg; i.g.; once) shows antihistaminic activity with an ED 50 of 2.73 mg/kg in pigs [1]. Animal Model: Male guinea-pigs [1] Dosage: 10 mL/kg Administration: Oral gavage, once Result: The ED 50 -value for a protection from a fatal histamine shock was calculated as 2.73 mg/kg when administered orally 1 h before the injection of histamine. The calculated oral anti-anaphylactic ED 50 -value was found to be >31.6mg/kg. The oral LD 50 -values was found to be 988 mg/kg. |
分子量 | 408.49 |
分子式 | C24H28N2O4 |
CAS No. | 136152-64-2 |
存储 | Shipping with blue ice. |
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