Casimersen

Name: Casimersen
Brand: TargetMol
SKU: T38859
Price: 282 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T38859Cas号 1422958-19-7

别名 SRP-4045

Casimersen (SRP-4045) is an antisense oligonucleotide, specifically belonging to the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, effectively restoring the open-reading frame by skipping exon 45. This action ultimately leads to the production of a functional dystrophin protein, albeit internally truncated. Casimersen finds utility in Duchenne muscular dystrophy (DMD) research.

Casimersen

还可以

产品编号 T38859 别名 SRP-4045Cas号 1422958-19-7

规格	价格	库存
1 mg	¥ 7,660	期货
5 mg	¥ 19,900	期货
10 mg	¥ 29,900	期货

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产品介绍

生物活性

产品描述	Casimersen (SRP-4045) is an antisense oligonucleotide, specifically belonging to the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, effectively restoring the open-reading frame by skipping exon 45. This action ultimately leads to the production of a functional dystrophin protein, albeit internally truncated. Casimersen finds utility in Duchenne muscular dystrophy (DMD) research.
体外活性	Exon 45 skipping is intended to allow for production of an internally truncated dystrophin protein in patients with genetic mutations that are amenable to exon 45 skipping[2].
别名	SRP-4045