购物车
- 全部删除
您的购物车当前为空
Anti-ICAM2 Monoclonal Antibody-PE
还可以产品编号 TMAZ-0408P
Anti-ICAM2 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting ICAM2. Anti-ICAM2 Monoclonal Antibody-PE can be used in FACS.
Anti-ICAM2 Monoclonal Antibody-PE
Anti-ICAM2 Monoclonal Antibody-PE
还可以产品编号 TMAZ-0408P
Anti-ICAM2 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting ICAM2. Anti-ICAM2 Monoclonal Antibody-PE can be used in FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 2,300 | 7日内发货 | |
| 50 μg | ¥ 3,833 | 7日内发货 | |
| 100 μg | ¥ 5,750 | 7日内发货 |
大包装 & 定制
加入购物车
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-ICAM2 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting ICAM2. Anti-ICAM2 Monoclonal Antibody-PE can be used in FACS. |
| 体外活性 | Rosiglitazone sodium是一种高效选择性的PPARγ激活剂，对PPARγ1和PPARγ2的EC50分别为30 nM和100 nM，且对PPARγ的Kd约为40 nM。Rosiglitazone (BRL49653，0.1, 1,10 μM)能促进C3H10T1/2干细胞分化成脂肪细胞。Rosiglitazone (Compound 6)通过EC50为60 nM激活PPARγ。Rosiglitazone (1 μM)激活PPARγ后，可促使其结合至NF-α1启动子以激活神经元中的基因转录。此外，Rosiglitazone (1 μM)还能保护Neuro2A细胞和海马神经元免受氧化应激，且依赖NF-α1的方式上调BCL-2表达。Rosiglitazone完全抑制TRPM3，针对尼菲地平(Nifedipine)和PregS诱导的活动的IC50值分别为9.5 μM和4.6 μM，但这种效应并非通过PPARγ途径。Rosiglitazone在较高浓度下抑制TRPM2，IC50约为22.5 μM。Rosiglitazone还是TRPC5通道的强力刺激剂，其EC50约为30 μM。 |
| 体内活性 | 在糖尿病大鼠中，Rosiglitazone (5 mg/kg, p.o.) 降低了血清中的葡萄糖水平，并减少了IL-6、TNF-α和VCAM-1的表达。此外，Rosiglitazone与losartan联合使用时，相较于仅糖尿病和仅接受Losartan治疗的组别，能显著提高葡萄糖水平。Rosiglitazone 显著改善了由PE和Ang II引起的显著较低的收缩反应和ACh促进的放松反应，从而改善了糖尿病大鼠分离的主动脉的内皮功能障碍。 |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 应用 | FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of ICAM2 protein. |
| 性状 | Liquid |
| 缓冲液 | Usually, for unconjugated and biotin antibody, 0.22 μm filtered solution in PBS. For APC/PE/AF647/AF555/AF488 conjugated antibody, 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 偶联 | PE |
| 其他可选修饰符 | Biotin/APC/AF488/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | ICAM2 |
| 抗原种属 | Human |
| 基因ID | 3384 |
| 研究领域 | Other Functions |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-ICAM2 Monoclonal Antibody-PE | purchase Anti-ICAM2 Monoclonal Antibody-PE | Anti-ICAM2 Monoclonal Antibody-PE cost | order Anti-ICAM2 Monoclonal Antibody-PE | Anti-ICAM2 Monoclonal Antibody-PE in vivo | Anti-ICAM2 Monoclonal Antibody-PE in vitro | Anti-ICAM2 Monoclonal Antibody-PE molecular weight
嗨！很高兴为您提供帮助！
评论内容