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BRD0418作为 TRIB1表达的上调因子,导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。
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BRD0418作为 TRIB1表达的上调因子,导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,290 | 现货 | |
5 mg | ¥ 2,990 | 现货 | |
10 mg | ¥ 4,390 | 现货 | |
25 mg | ¥ 6,910 | 现货 | |
50 mg | ¥ 9,480 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 3,430 | 现货 |
产品描述 | BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it. |
体外活性 | Treatment of HepG2 cells with BRD0418 for 6 hours resulted on average in 3.5-fold up-regulation of TRIB1 transcript levels, with half-maximal effect achieved at 2.3 μM concentration of the compound[1]. |
别名 | BRD-0418, BRD 0418 |
分子量 | 488.57 |
分子式 | C29H32N2O5 |
CAS No. | 1565827-99-7 |
Smiles | C(O)[C@H]1[C@]2([C@](C=3C(O2)=CC=C(N(C)C)C3)(C[C@@H](CC(NCC4=CC=C(OC5=CC=CC=C5)C=C4)=O)O1)[H])[H] |
密度 | 1.220 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 55 mg/mL (112.57 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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