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Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms (IC50: 0.025 μM, 6.4 μM, 1.1 μM, and 4.5 μM for SmChiA [Serratia marcescens chitinase A], SmChiB, Aspergillus fumigatus chitinase B1, and human chitotriosidase).
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms (IC50: 0.025 μM, 6.4 μM, 1.1 μM, and 4.5 μM for SmChiA [Serratia marcescens chitinase A], SmChiB, Aspergillus fumigatus chitinase B1, and human chitotriosidase).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms (IC50: 0.025 μM, 6.4 μM, 1.1 μM, and 4.5 μM for SmChiA [Serratia marcescens chitinase A], SmChiB, Aspergillus fumigatus chitinase B1, and human chitotriosidase). |
靶点活性 | SmChiB:6.4 μM , Chitotriosidase (human):4.5 μM , Chitinase B1 (aspergillus fumigatus):1.1 μM , SmChiA:0.025 μM |
体外活性 | Argifin inhibits L. cuprina chitinase (IC50s: 3.7 μM at 37 oC and 0.10 μM at 20 oC) |
分子量 | 675.7 |
分子式 | C29H41N9O10 |
CAS No. | 243975-37-3 |
密度 | 1.49 g/cm3 (Predicted) |
存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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