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Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.
Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥ 5,533 | 5日内发货 |
产品描述 | Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB. |
体外活性 | It acts through two types of receptors: ETA and ETB.?Apart from a vasoconstrictive action, ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species.?It is claimed that ET-1 induces proinflammatory mechanisms, increasing superoxide anion production and cytokine secretion.Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells. |
别名 | 内皮缩血管肽 1 (猪,人) |
分子量 | 2491.9 |
分子式 | C109H159N25O32S5 |
CAS No. | 117399-94-7 |
密度 | 1.273 g/cm3 (Predicted) |
存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
溶解度信息 | H2O: 50 mg/mL (20.07 mM), Sonication is recommended. | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
H2O
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