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Anti-AGT Monoclonal Antibody-AF647

产品编号 TMAZ-0159A6
别名 Angiotensinogen, Serpin A8

Anti-AGT Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody-AF647 can be used in ELISA, FACS.

Anti-AGT Monoclonal Antibody-AF647

Anti-AGT Monoclonal Antibody-AF647

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产品编号 TMAZ-0159A6 别名 Angiotensinogen, Serpin A8

Anti-AGT Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody-AF647 can be used in ELISA, FACS.

规格价格库存数量
25 μg¥ 2,087.42¥ 3,5997日内发货
50 μg¥ 3,478.84¥ 5,9987日内发货
100 μg¥ 5,218.26¥ 8,9977日内发货
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产品介绍

生物活性
产品描述
Anti-AGT Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody-AF647 can be used in ELISA, FACS.
别名Angiotensinogen, Serpin A8
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of AGT overexpressed 435F cells with TMAZ-0159A6, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of AGT protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis|Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone (PubMed: 10619573, PubMed: 17138938). Acts by binding to angiotensin receptors AGTR1 and AGTR2 (PubMed: 1567413). Also binds the DEAR/FBXW7-AS1 receptor (By similarity)|Stimulates aldosterone release|Is a ligand for the G-protein coupled receptor MAS1 (By similarity). Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets (By similarity)
偶联与修饰
偶联
AF647
其他可选修饰符
Biotin/APC/PE/AF488/AF555
可提供抗体种类
5
抗原信息
免疫原
AGT
抗原种属
Human
基因ID
183
Uniprot ID
研究领域
Drug Target
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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