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SMP-028
还可以产品编号 T12936Cas号 914389-14-3
SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM).
SMP-028
还可以产品编号 T12936Cas号 914389-14-3
SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 10,600 | 6-8周 | |
| 50 mg | ¥ 13,800 | 6-8周 | |
| 100 mg | ¥ 17,500 | 6-8周 |
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产品介绍
生物活性
化学信息
| 产品描述 | SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM). |
| 靶点活性 | CEase:1.01 μM |
| 体外活性 | SMP-028 potently and concentration-dependently inhibits neutral cholesterol esterase (CEase)(IC50: 1.01 μM). On the other hand, SMP-028 inhibitS other steroidogenic enzymes is weak with IC50 values>10 μM. In particular, SMP-028 does not inhibit acid CEase and only weakly reduces the activity of CYP11A1 with IC50 values>100 μM and 49.8 μM. respectively [1]. SMP-028 at 10 μM or less does not affect the viability of male adrenal cells, female adrenal cells, testicular cells, and ovarian cells. SMP-028 at concentrations higher than 30 μM significantly reduce the viability of male adrenal cells, female adrenal cells [2]. |
| 分子量 | 455.55 |
| 分子式 | C23H26FN5O2S |
| CAS No. | 914389-14-3 |
| 密度 | 1.32 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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