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AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. |
体外活性 | AT-1002 reversibly increases the paracellular transport of molecules across the epithelial barrier. AT-1002 can undergo Cys-Cys dimerization [1]. Undifferentiated Caco-2 cells are treated with AT-1002 (0 to 5 mg/mL, 3 or 24 hours) and viability is assessed by measuring cellular ATP content. Treatment with AT-1002 for up to 3 h does not affect cell viability at any concentration. In particular, the viability of Caco-2 cells is not affected by 5 mg/mL AT-1002. AT-1002 reduces cell viability after 24 h at concentrations of 2.5 mg/mL and higher. However, the cells remain viable after 24 h if the cells are washed after exposure to AT-1002 for 3 h [2]. |
分子量 | 707.88 |
分子式 | C32H53N9O7S |
CAS No. | 835872-35-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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