Rovanersen

Name: Rovanersen
Brand: TargetMol
SKU: T39479
Price: 113 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T39479Cas号 2072901-32-5

别名 WVE-120101, Rovanersen

Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.

还可以

产品编号 T39479 别名 WVE-120101, RovanersenCas号 2072901-32-5

Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.

规格	价格	库存	数量
5 mg	¥ 6,170	期货

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产品介绍

生物活性

产品描述	Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.
体外活性	In vitro, Rovanersen (WVE-120101) leads to the selective RNase H cleavage of mutant Huntingtin allele (mHTT) over wtHTT, with no complement activation. Rovanersen selectively decreases mHTT mRNA and protein levels compared with wtHTT in multiple cells lines[1].
体内活性	In non-human primates (NHPs), Rovanersen (WVE-120101) is found in nuclear and perinuclear compartments of neurons in brain areas believed to be involved in HD pathology[1].
别名	WVE-120101, Rovanersen