Patisiran sodium

Name: Patisiran sodium
Brand: TargetMol
SKU: T38804
Rating: 4.5 (1 reviews)

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产品编号 T38804Cas号 1386913-72-9

Patisiran sodium is a double-stranded small interfering RNA (siRNA) that selectively targets a specific sequence within the transthyretin (TTR) messenger RNA (mRNA). By doing so, it effectively blocks the hepatic synthesis of both mutant and wild-type TTR. Patisiran sodium has significant applications in the field of hereditary TTR amyloidosis research.

Patisiran sodium

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产品编号 T38804Cas号 1386913-72-9

规格	价格	库存	数量
1 mg	¥ 6,650	期货
5 mg	¥ 19,900	期货

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产品描述	Patisiran sodium is a double-stranded small interfering RNA (siRNA) that selectively targets a specific sequence within the transthyretin (TTR) messenger RNA (mRNA). By doing so, it effectively blocks the hepatic synthesis of both mutant and wild-type TTR. Patisiran sodium has significant applications in the field of hereditary TTR amyloidosis research.
体外活性	Patisiran sodium causes TTR degradation (via RNA interference) and subsequently a reduction in serum TTR protein levels and tissue TTR protein deposits by specifically binding to a genetically conserved sequence in the 3' untranslated region of mutant and wild-type transthyretin (TTR) messenger RNA[2].