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Anti-PSAP Monoclonal Antibody-APC

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产品编号 TMAZ-0240A
别名 Prosaposin, Proactivator polypeptide

Anti-PSAP Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting PSAP. Anti-PSAP Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

Anti-PSAP Monoclonal Antibody-APC

Anti-PSAP Monoclonal Antibody-APC

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产品编号 TMAZ-0240A 别名 Prosaposin, Proactivator polypeptide

Anti-PSAP Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting PSAP. Anti-PSAP Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 3,5997日内发货
50 μg¥ 5,9987日内发货
100 μg¥ 8,9977日内发货
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产品介绍

生物活性
产品描述
Anti-PSAP Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting PSAP. Anti-PSAP Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
别名Prosaposin, Proactivator polypeptide
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of PSAP overexpressed 335F cells with TMAZ-0240A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of PSAP protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate|Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases|Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12)|Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling|Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases
偶联与修饰
偶联
APC
其他可选修饰符
Biotin/PE/AF488/AF555/AF647
可提供抗体种类
3
抗原信息
免疫原
PSAP
抗原种属
Human
基因ID
5660
Uniprot ID
研究领域
Other Functions
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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