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Anti-KITLG Monoclonal Antibody-APC

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产品编号 TMAZ-0211A
别名 Stem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand

Anti-KITLG Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

Anti-KITLG Monoclonal Antibody-APC

Anti-KITLG Monoclonal Antibody-APC

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产品编号 TMAZ-0211A 别名 Stem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand

Anti-KITLG Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 1,4637日内发货
50 μg¥ 2,4387日内发货
100 μg¥ 3,6577日内发货
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产品介绍

生物活性
产品描述
Anti-KITLG Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KITLG. Anti-KITLG Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
别名Stem cell factor, Mast cell growth factor, Kit ligand, c-Kit ligand
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of KITLG overexpressed 427F cells with TMAZ-0211A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KITLG protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins
偶联与修饰
偶联
APC
其他可选修饰符
Biotin/PE/AF488/AF555/AF647
可提供抗体种类
2
抗原信息
免疫原
KITLG
抗原种属
Human
基因ID
4254
Uniprot ID
研究领域
Cytokines
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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