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Anti-EPOR Monoclonal Antibody-APC

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产品编号 TMAZ-0026A
别名 Erythropoietin receptor

Anti-EPOR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

Anti-EPOR Monoclonal Antibody-APC

Anti-EPOR Monoclonal Antibody-APC

Rating icon 还可以
产品编号 TMAZ-0026A 别名 Erythropoietin receptor

Anti-EPOR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-APC can be used in ELISA, FACS, IF.

规格价格库存数量
25 μg¥ 3,5997日内发货
50 μg¥ 5,9987日内发货
100 μg¥ 8,9977日内发货
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产品介绍

生物活性
产品描述
Anti-EPOR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EPOR. Anti-EPOR Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
别名Erythropoietin receptor
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of EPOR overexpressed 371F cells with TMAZ-0026A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
ELISA, FACS, IF
推荐剂量
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EPOR protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
纯度> 95% as determined by SDS-PAGE.
研究背景Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed: 10388848, PubMed: 2163695, PubMed: 2163696, PubMed: 8662939, PubMed: 9774108). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (By similarity). In some cell types, can also activate STAT1 and STAT3 (PubMed: 11756159). May also activate the LYN tyrosine kinase (By similarity)|Acts as a dominant-negative receptor of EPOR-mediated signaling
偶联与修饰
偶联
APC
其他可选修饰符
Biotin/PE/AF488/AF555/AF647
可提供抗体种类
2
抗原信息
免疫原
EPOR
抗原种属
Human
基因ID
2057
Uniprot ID
研究领域
Immunology Research
化学信息
分子量150 kDa
存储&运输
储存方式For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
运输方式For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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