首页工具

登录

搜索结果

Search Results for " type i receptor kinases "

Targets Recommended: ALK TGF-beta/Smad

2

抑制剂 & 化合物

7

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1944	LDN-214117	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	LDN214117 是一种高效的 ALK2 选择性抑制剂(IC50:22nM)，也是一种 BMP6 抑制剂(IC50:100nM)，对ALK5抑制力弱100倍。
T6158	LDN-193189 HCl LDN193189 Hydrochloride	ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	LDN-193189 HCl (LDN193189 Hydrochloride) 是一种选择性 BMP I 型受体激酶抑制剂。

化合物

Cat.No: T1944

Target: ALK, TGF-beta/Smad

Cat.No: T6158

Synonym: LDN193189 Hydrochloride

Target: ALK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00315	ACVR2A Protein, Human, Recombinant (hFc & His) ACTR-IIA,Activin Rec...	Human	HEK293 Cells
	Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors....
TMPJ-01323	NTAL Protein, Human, Recombinant (His) Williams-Beuren Syndrome Chromosomal Reg	Human	HEK293 Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPJ-00712	MPZL1 Protein, Human, Recombinant (His) FLJ96614,mRNA,Myelin protein zero-li	Human	HEK293 Cells
	Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin...
TMPJ-00403	EphB1 Protein, Human, Recombinant (hFc) EPHT2,EPH Tyrosine Kinase 2,EK6,Tyrosi...	Human	HEK293 Cells
	Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule i...
TMPJ-00230	EFNB1 Protein, Mouse, Recombinant (hFc & His) EFNB1,LERK-2,EPH-related receptor tyrosine...	Mouse	HEK293 Cells
	Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Ephrin-B1 is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on...
TMPJ-00329	CD19 Protein, Rhesus macaque, Recombinant (hFc) B-Lymphocyte Antigen CD19,CD19,Different	Rhesus	HEK293 Cells
	CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Sr...
TMPJ-00224	EFNB2 Protein, Mouse, Recombinant (hFc & His) Ephrin-B2,Htkl,Lerk5.,ELF-2,Epl5,Eplg5,EPH-related ...	Mouse	HEK293 Cells
	Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The ephrins and EPH-related receptors contain the largest subfamily of receptor protein-tyrosine kinases and have been associated ...

重组蛋白

ACVR2A Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00315

Species: Human

Expression System: HEK293 Cells

NTAL Protein, Human, Recombinant (His)

Cat.No: TMPJ-01323

Species: Human

Expression System: HEK293 Cells

MPZL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00712

Species: Human

Expression System: HEK293 Cells

EphB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00403

Species: Human

Expression System: HEK293 Cells

EFNB1 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00230

Species: Mouse

Expression System: HEK293 Cells

CD19 Protein, Rhesus macaque, Recombinant (hFc)

Cat.No: TMPJ-00329

Species: Rhesus

Expression System: HEK293 Cells

EFNB2 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00224

Species: Mouse

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼