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Cat. No. Product Name
L4710 非甾体类抗炎化合物库

530 compounds
530 种非甾体类的抗炎相关化合物,可用于高通量和高内涵筛选;
L1510 核受体化合物库

531 compounds
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L6800 中国药典收录天然产物库

2051 compounds
2051 种中国药典收录的天然产物,是药物开发、药理研究等领域的有力工具;
L6810 中药单体化合物库

2755 compounds
2755 种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具;

化合物库

非甾体类抗炎化合物库
Cat.No: L4710
Compounds: 530
核受体化合物库
Cat.No: L1510
Compounds: 531
中国药典收录天然产物库
Cat.No: L6800
Compounds: 2051
中药单体化合物库
Cat.No: L6810
Compounds: 2755
Cat. No. Product Name Target Signaling Pathways
T61687 Steroid sulfatase-IN-1

Others Others
Steroid sulfatase-IN-1 is a highly potent and orally active inhibitor of the enzyme Steroid sulfatase, with an impressive IC50 value of 1.71 μM. This compound exhibits notable antitumor activity, achieving a TGI (tumor growth inhibition) of 51% in vivo. Therefore, Steroid sulfatase-IN-1 holds great promise in the field of breast cancer research [1].
T61686 Steroid sulfatase-IN-3

Others Others
Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-dependent breast cancer cells, with an IC 50 of 1.04 μM [1].
T62237 Steroid sulfatase-IN-4

Others Others
Steroid sulfatase-IN-4 (Compound 16) 是一种类固醇硫酸酯酶 (STS) 的不可逆抑制剂,能够作用于人 STS (IC50: 25 nM)。Steroid sulfatase-IN-4 能够用于研究子宫内膜异位。
T81091 Steroid sulfatase-IN-5

Others Others
Steroid sulfatase-IN-5 (compound 10b) 是一种高效的STS抑制剂,具有0.32 nM的IC50值。该化合物还能显著抑制T-47D细胞增殖,其IC50为35.7 μM,常用于乳腺癌相关的研究领域。
T81089 Steroid sulfatase-IN-7

Others Others
Steroid sulfatase-IN-7是一种具有高度选择性的不可逆STS抑制剂,表现出0.05 nM的强效对人胎盘STS抑制能力,常被用于癌症方面的科学研究。
T61212 Steroid sulfatase-IN-2

Others Others
Steroid sulfatase-IN-2 is an active inhibitor of steroid sulfatase (STS), demonstrating an IC50 value of 109.5 nM. Its potential application lies in hormone-dependent cancer research, specifically estrogen-dependent breast and endometrial cancer [1].
T81090 Steroid sulfatase-IN-6

Others Others
Steroid sulfatase-IN-6 (Compound 10c) 是一种针对类固醇硫酸酯酶 (STS) 的不可逆抑制剂,对人胎盘 STS 的 Ki 值达到 0.4 nM。该化合物适用于肿瘤疾病研究。
T83752 Biotin-SRC-1 (676–700) TFA

Biotin-Steroid Receptor Coactivator 1 (676-700)

Biotin-SRC-1 (676–700)是一种生物素化且缩短的类固醇受体辅助激活蛋白1 (SRC-1)。它已在基于亲和力的报告试验中使用,包括时间分辨荧光共振能量转移 (TR-FRET) 和增强型近距离发光均匀检测法 (ΑLPHASCREEN™)。
T81092 Steroid sulfatase/17β-HSD1-IN-5

Others Others
Steroid sulfatase/17β-HSD1-IN-5 是一种不可逆抑制剂,针对类固醇硫酸酯酶(STS),同时也是17β-羟甾类固醇脱氢酶1型(17β-HSD1)的可逆且选择性抑制剂,表现出对17β-HSD1的IC50为43 nM,对17β-HDS1为6.2 μM。该化合物主要用于研究代谢性疾病,特别是子宫内膜异位症。
T61716 Steroid sulfatase/17β-HSD1-IN-1

Others Others
Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities, displaying an IC50 value of 28 nM against cellular human steroid sulfatase. This compound holds significant potential for investigating estrogen-dependent diseases [1].
T61979 Steroid sulfatase/17β-HSD1-IN-4

Others Others
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) 是一种类固醇硫酸酯酶 (STS) 和 17β-羟基类固醇脱氢酶 1 型 (17β HSD1) 双重抑制剂。Steroid sulfatase/17β-HSD1-IN-4 对 hSTS 的活性抑制作用不可逆,IC50为 63 nM。Steroid sulfatase/17β-HSD1-IN-4 在子宫内膜异位症及其他雌激素依赖性疾病方面有研究价值。
T62236 Steroid sulfatase/17β-HSD1-IN-3

Others Others
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) 是一种双重的类固醇硫酸酯酶 (STS) 和 17β-羟基类固醇脱氢酶 1 型 (17β HSD1) 抑制剂。Steroid sulfatase/17β-HSD1-IN-3 对 hSTS 的活性具有不可逆的抑制作用 (IC50: 27 nM)。Steroid sulfatase/17β-HSD1-IN-3 能够用于研究子宫内膜异位症及其他雌激素依赖性疾病。
T0181 Loteprednol etabonate

Lotemax,Alrex,氯替泼诺

Glucocorticoid Receptor; Antibacterial; Antibiotic Endocrinology/Hormones; Microbiology/Virology
Loteprednol etabonate (Lotemax) 是具有抗炎活性的皮质类固醇,用于眼科。
T0166 Pancuronium dibromide

Pancuronium bromide,Pavulon,泮库溴铵

AChR Neuroscience
Pancuronium dibromide (Pavulon) 是一种双季基类固醇,是一种神经肌肉松弛剂。它通过与乙酰胆碱竞争 nACh 受体上的结合位点来抑制神经肌肉传递。它还可抑制心脏毒蕈碱受体并具有拟交感神经作用。
T1531 Mometasone furoate

糠酸莫美他松,糠酸莫米松,Sch32088

Glucocorticoid Receptor Endocrinology/Hormones
Mometasone furoate (Sch32088) 是糖皮质激素受体激动剂,具有抗炎和抗过敏作用。它是皮质固醇类试剂,动物模型中,可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
T1167 Cyproterone acetate

Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮

Androgen Receptor Endocrinology/Hormones
Cyproterone acetate (Cyproterone 17-O-acetate) 是能够抗雄激素(IC50=7.1 nM) 和孕激素合成的类固醇。它与 progesteron 和糖皮质激素受体有亲和力。
T61444 Nonsteroidal aromatase inhibitor 1

Others Others
Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for research in the field of breast cancer [1].
T76147 3α-Hydroxysteroid dehydrogenase

Others Others
3α-Hydroxysteroid dehydrogenase(3α-HSD) 是一种由 AKR1C4 基因编码的酶,可以催化 3-酮类甾体转化为 3α-羟基化合物。3α-Hydroxysteroid dehydrogenase 在雄激素 DHT 的失活中起重要作用,可以将 DHT 转化成雄激素活性很弱的 3α-雄烷二醇,可用于多毛症研究。
T4464 Irosustat

667-Coumate,BN83495,STX64

Others Others
Irosustat (667-Coumate) 是类固醇硫酸酯酶抑制剂(IC50:8 nM),具有抗乳腺癌作用。
T0293 Metyrapone

美替拉酮,甲吡酮,NSC-25265,Su-4885

Others; P450; Dehydrogenase; Autophagy Autophagy; Metabolism; Others
Metyrapone (NSC-25265) 是 STEROID 11-BETA-MONOOXYGENASE 酶抑制剂。 它被用作库欣综合征诊断中下丘脑-垂体反馈机制的测试。
T2559 Allylestrenol

Gestanon,Gestanol,烯丙雌醇,Gestanin

Estrogen/progestogen Receptor Endocrinology/Hormones
Allylestrenol (Gestanin) 是合成的性类固醇,在世界范围内用于濒危怀孕。
T84308 3,5,6-trihydroxysitostane

(24R)-Stigmastane-3β,5α,6α-triol

3,5,6-trihydroxysitostane 是一种从吴茱萸果实中提取的类固醇天然产物。
T3137 Boldenone Undecylenate

Parenabol,Ba 29038,Vebonol,十一碳烯酸去甲睾酮

Androgen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Boldenone Undecylenate (Parenabol) 十一碳烯酸盐一种是人工合成的甾体,作用与天然的睾酮相似。
T0870 Altrenogest

R2267,RU2267,Allyltrenbolone,A35957,烯丙孕素

Estrogen/progestogen Receptor; Progesterone Receptor Endocrinology/Hormones; Others
Altrenogest (Allyltrenbolone) 是一种结构与trenbolone 相关的孕激素,能作用于孕激素受体。
T83615 S5A1

Others Others
S5A1 是一种合成的类固醇,可用于研究糖尿病。
T21452 Anecortave Acetate

Retaane,Al 3789,NSC 24345,NSC 15475,Anecortave

Others Others
Anecortave Acetate (NSC-24345) 是一种血管抑制类固醇,用于蛋白质组学研究。
T60929 Brassinazole

(2S,3R)-Brassinazole

Others Others
Brassinazole 是一种选择性的三唑型类固醇 (BR)生物合成抑制剂。Brassinazole 可用于调节油芸素类固醇 (BR) 信号转导通路,用于调节植物木质部的生长和发育。
T27478 GSK3987

Liver X Receptor Metabolism
GSK3987 是广谱LXRα/β激动剂,EC50分别为 50 nM 和 40 nM。GSK3987增加 ABCA1 和 SREBP-1c 蛋白的表达,诱导细胞甘油三酯的积累和胆固醇流出。
T5326 Sugammadex sodium

Org25969,Sugammadex (sodium),舒更葡糖钠

Others Others
Sugammadex sodium (Org25969) 是合成的 γ 环糊精衍生物,是一种新型的神经肌肉阻断逆转剂。
T6502 Fluocinonide

醋酸氟轻松,Lidex,Metosyn,氟轻松,Topsyn

Glucocorticoid Receptor Endocrinology/Hormones
Fluocinonide (Topsyn) 是一种糖皮质激素类固醇,具有抗炎作用,可作用于皮肤疾病的研究。
T6465 Dexamethasone Sodium Phosphate

Dexadreson,地塞米松磷酸钠,Dexagro,Dalalone

IL Receptor; COX Immunology/Inflammation; Neuroscience
Dexamethasone Sodium Phosphate (Dexadreson) 是一种白细胞介素受体调节剂,具有抗炎和免疫抑制作用。它属于类固醇合成药物的强效糖皮质激素类。
T0384 Estradiol benzoate

Benzoestrofol,Benzhormovarine,苯甲酸雌二醇,Benovocylin

Estrogen Receptor/ERR; Estrogen/progestogen Receptor Endocrinology/Hormones
Estradiol benzoate (Benzhormovarine) 是一种类固醇性激素,是一种雌二醇的前体药物。它表现出轻微的合成代谢特性,增加血液凝固性。
T2199 Myclobutanil

Systhane,腈菌唑

Antifungal Microbiology/Virology
Myclobutanil (Systhane) 是康唑类抗真菌剂,可用作农药。
T6503 Fluorometholone Acetate

NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate

Glucocorticoid Receptor; Carbonic Anhydrase Endocrinology/Hormones; Metabolism
Fluorometholone Acetate (Oxylone acetate) 是合成的糖皮质激素皮质类固醇及皮质类固醇酯。它有效抑制碳酸酐酶 (CA) 对 hCA-I(IC50:2.18 μM)和 hCA-II(IC50:17.5 μM)。它具有抗炎活性,可用于研究外部眼部炎症。
T13684 Equilin

7-Dehydroestrone

Calcium Channel Membrane transporter/Ion channel; Metabolism
Equilin (7-Dehydroestrone) 是神经营养性雌激素类固醇,具有血管扩张活性,通过 NF-κB 信号传导增加单核细胞-内皮粘附。Equilin 通过阻断Ca(2+)进入平滑肌来同样放松肠系膜动脉的阻力。
T1594 Vecuronium bromide

ORG NC 45,维库溴铵

AChR Neuroscience
Vecuronium bromide (ORG NC 45) 是一种合成的中效单季铵盐类固醇和非去极化神经肌肉阻滞剂,具有肌肉松弛活性。
T6215 Abiraterone Acetate

Zytiga,乙酸阿比特龙酯,CB7630

P450 Metabolism
Abiraterone Acetate (CB7630) 是一种具有口服活性的、不可逆的 CYP17A1选择性抑制剂,具有抗雄激素作用。它是 Abiraterone 的前药。
T6886 MCB-613

MCB 613

Src Angiogenesis; Tyrosine Kinase/Adaptors
MCB-613 是类固醇受体共激活因子 (SRC) 小分子“刺激物” (SMS),超刺激 SRCs 的转录活性。它促进 SRC 与其他共激活因子发生相互作用,并显著诱导 ER 应激与活性氧的产生相结合。它是一种 SMS,能够过度刺激 SRC 致癌程序,靶向癌基因用作抗癌药物。
T23549 YM 511

P450; Aromatase Endocrinology/Hormones; Metabolism
YM 511 是一种高度特异性的非甾体芳香酶 (aromatase) 抑制剂。YM 511 竞争性抑制大鼠卵巢和人胎盘微粒体中的芳香酶活性 (IC50 分别为 0.4 和 0.12 nM)。YM 511 轻微抑制其他类固醇激素的产生。YM 511 具有用于抑制雌激素依赖性作用研究,不会影响其他类固醇激素的血清水平的潜力。
T15000 Cort108297

Glucocorticoid Receptor Endocrinology/Hormones
Cort108297是一种选择性糖皮质激素受体调节剂,也是一种对其他类固醇受体无亲和力的选择性GR 拮抗剂。Cort108297对gr 具有较高的亲和力(Ki: 0.45 nM)。
T67901 SRD5A1-IN-1

Others Others
SRD5A1-IN-1 是类固醇 5α-还原酶 1 型的抑制剂(SRD5A1,IC50 = 1.44 µM)。 SRD5A1-IN-1 可降低二氢睾酮的产生并显着降低 SRD5A1 蛋白表达。
T0947 Dexamethasone acetate

Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471

Glucocorticoid Receptor; Mitophagy; IL Receptor; Annexin A; NOS; Antibacterial; Autophagy; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体,有抗炎和免疫抑制活性。它可研究眼部感染。
T25458 Golexanolone

Golexanolonum,Golexanolona,GR-3027

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Golexanolone (Golexanolona) 是一种新的 GABA-A 受体调节类固醇拮抗剂,可减少外周炎症和神经炎症,并改善慢性高氨血症大鼠的认知和运动功能,可用于研究肝性脑病。
T3316 Fluorometholone

氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson

Glucocorticoid Receptor Endocrinology/Hormones
Fluorometholone (Fluoromethalone) 是合成糖皮质激素,具有抗炎和抗过敏作用。它可用作糖皮质激素受体激动剂,能够用于干眼症的研究。
T1438 Butoconazole nitrate

RS 35887,硝酸布康唑

Estrogen/progestogen Receptor; Antifungal Endocrinology/Hormones; Microbiology/Virology
Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
T2556 Nandrolone decanoate

癸酸诺龙,19-Nortestosterone decanoate

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素,通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T60924 Verosudil

AR-12286

ROCK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
Verosudil (AR-12286) 是一种高效的 Rho 激酶 (ROCK) 抑制剂,对 ROCK1 和 ROCK2 的 Ki 分别为 2 和 2 nM。AR-12286 可逆转类固醇诱导的小鼠眼内压,可通过增加眼房水通过小梁网流出来减缓眼压。
T72470 Estrone O-sulfamate

Estrone 3-O-sulfamate

Others Others
Estrone O-sulfamate (Estrone 3-O-sulfamate) 是一种高效的的类固醇硫酸酯酶 (STS) 抑制剂。Estrone O-sulfamate 是一种胎盘微粒体抑制剂 (P.M.) ,IC50 值分别为 18 nM。Estrone O-sulfamate 在 MCF-7 细胞中对 STS 显示出抑制作用,IC50 值分别为 0.83 nM。Estrone O-sulfamate 可用于研究癌症。
T28773 SI-2

SI2,EPH 116,EPH116,EPH-116

Others Others
SI-2是类固醇受体辅激活因子-3(SRC-3或 AIB1)的抑制剂(SMI)。SI-2可选择性降低细胞中 SRC-3的转录活性和蛋白浓度,并选择性诱导低纳摩尔范围(3-20 nM)内的乳腺癌症细胞死亡,但不影响正常细胞存活率。
T9836 (E)-SI-2

Others Others
(E)-SI-2 是类固醇受体 coactivator-3(SRC-3 或 AIB1)的有效小分子抑制剂,可选择性抑制 SRC-3 的内在转录活性,也抑制 SRC-1 和 SRC-2。它选择性地降低 SRC-3 的细胞蛋白水平,但不降低 CARM-1 的细胞蛋白水平,阻断 MDA-MB-468 细胞生长,IC50 值为 3.4 nM,但不影响正常细胞。

化合物

Steroid sulfatase-IN-1
Cat.No: T61687
Synonym:
Target: Others
Steroid sulfatase-IN-3
Cat.No: T61686
Synonym:
Target: Others
Steroid sulfatase-IN-4
Cat.No: T62237
Synonym:
Target: Others
Steroid sulfatase-IN-5
Cat.No: T81091
Synonym:
Target: Others
Steroid sulfatase-IN-7
Cat.No: T81089
Synonym:
Target: Others
Steroid sulfatase-IN-2
Cat.No: T61212
Synonym:
Target: Others
Steroid sulfatase-IN-6
Cat.No: T81090
Synonym:
Target: Others
Biotin-SRC-1 (676–700) TFA
Cat.No: T83752
Synonym: Biotin-Steroid Receptor Coactivator 1 (676-700)
Target:
Steroid sulfatase/17β-HSD1-IN-5
Cat.No: T81092
Synonym:
Target: Others
Steroid sulfatase/17β-HSD1-IN-1
Cat.No: T61716
Synonym:
Target: Others
Steroid sulfatase/17β-HSD1-IN-4
Cat.No: T61979
Synonym:
Target: Others
Steroid sulfatase/17β-HSD1-IN-3
Cat.No: T62236
Synonym:
Target: Others
Loteprednol etabonate
Cat.No: T0181
Synonym: Lotemax,Alrex,氯替泼诺
Target: Glucocorticoid Receptor, Antibacterial, Antibiotic
Pancuronium dibromide
Cat.No: T0166
Synonym: Pancuronium bromide,Pavulon,泮库溴铵
Target: AChR
Mometasone furoate
Cat.No: T1531
Synonym: 糠酸莫美他松,糠酸莫米松,Sch32088
Target: Glucocorticoid Receptor
Cyproterone acetate
Cat.No: T1167
Synonym: Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮
Target: Androgen Receptor
Nonsteroidal aromatase inhibitor 1
Cat.No: T61444
Synonym:
Target: Others
3α-Hydroxysteroid dehydrogenase
Cat.No: T76147
Synonym:
Target: Others
Irosustat
Cat.No: T4464
Synonym: 667-Coumate,BN83495,STX64
Target: Others
Metyrapone
Cat.No: T0293
Synonym: 美替拉酮,甲吡酮,NSC-25265,Su-4885
Target: Others, P450, Dehydrogenase, Autophagy
Allylestrenol
Cat.No: T2559
Synonym: Gestanon,Gestanol,烯丙雌醇,Gestanin
Target: Estrogen/progestogen Receptor
3,5,6-trihydroxysitostane
Cat.No: T84308
Synonym: (24R)-Stigmastane-3β,5α,6α-triol
Target:
Boldenone Undecylenate
Cat.No: T3137
Synonym: Parenabol,Ba 29038,Vebonol,十一碳烯酸去甲睾酮
Target: Androgen Receptor, Endogenous Metabolite
Altrenogest
Cat.No: T0870
Synonym: R2267,RU2267,Allyltrenbolone,A35957,烯丙孕素
Target: Estrogen/progestogen Receptor, Progesterone Receptor
S5A1
Cat.No: T83615
Synonym:
Target: Others
Anecortave Acetate
Cat.No: T21452
Synonym: Retaane,Al 3789,NSC 24345,NSC 15475,Anecortave
Target: Others
Brassinazole
Cat.No: T60929
Synonym: (2S,3R)-Brassinazole
Target: Others
GSK3987
Cat.No: T27478
Synonym:
Target: Liver X Receptor
Sugammadex sodium
Cat.No: T5326
Synonym: Org25969,Sugammadex (sodium),舒更葡糖钠
Target: Others
Fluocinonide
Cat.No: T6502
Synonym: 醋酸氟轻松,Lidex,Metosyn,氟轻松,Topsyn
Target: Glucocorticoid Receptor
Dexamethasone Sodium Phosphate
Cat.No: T6465
Synonym: Dexadreson,地塞米松磷酸钠,Dexagro,Dalalone
Target: IL Receptor, COX
Estradiol benzoate
Cat.No: T0384
Synonym: Benzoestrofol,Benzhormovarine,苯甲酸雌二醇,Benovocylin
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Myclobutanil
Cat.No: T2199
Synonym: Systhane,腈菌唑
Target: Antifungal
Fluorometholone Acetate
Cat.No: T6503
Synonym: NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate
Target: Glucocorticoid Receptor, Carbonic Anhydrase
Equilin
Cat.No: T13684
Synonym: 7-Dehydroestrone
Target: Calcium Channel
Vecuronium bromide
Cat.No: T1594
Synonym: ORG NC 45,维库溴铵
Target: AChR
Abiraterone Acetate
Cat.No: T6215
Synonym: Zytiga,乙酸阿比特龙酯,CB7630
Target: P450
MCB-613
Cat.No: T6886
Synonym: MCB 613
Target: Src
YM 511
Cat.No: T23549
Synonym:
Target: P450, Aromatase
Cort108297
Cat.No: T15000
Synonym:
Target: Glucocorticoid Receptor
SRD5A1-IN-1
Cat.No: T67901
Synonym:
Target: Others
Dexamethasone acetate
Cat.No: T0947
Synonym: Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471
Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy, ADC Cytotoxin
Golexanolone
Cat.No: T25458
Synonym: Golexanolonum,Golexanolona,GR-3027
Target: GABA Receptor
Fluorometholone
Cat.No: T3316
Synonym: 氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson
Target: Glucocorticoid Receptor
Butoconazole nitrate
Cat.No: T1438
Synonym: RS 35887,硝酸布康唑
Target: Estrogen/progestogen Receptor, Antifungal
Nandrolone decanoate
Cat.No: T2556
Synonym: 癸酸诺龙,19-Nortestosterone decanoate
Target: Others, HIV Protease
Verosudil
Cat.No: T60924
Synonym: AR-12286
Target: ROCK
Estrone O-sulfamate
Cat.No: T72470
Synonym: Estrone 3-O-sulfamate
Target: Others
SI-2
Cat.No: T28773
Synonym: SI2,EPH 116,EPH116,EPH-116
Target: Others
(E)-SI-2
Cat.No: T9836
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T8709 Nandrolone phenylpropionate

Nandrolone phenpropionate,苯丙酸诺龙

Androgen Receptor Endocrinology/Hormones
Nandrolone phenylpropionate (Nandrolone phenpropionate) 是一种合成代谢类固醇,是一种 19-nortestosterone 的衍生物。它能够促进蛋白质合成,用于缓解组织分解代谢,可以用于骨质疏松症和特纳综合征的研究。
T5S1982 Periplocin

Periplocoside,杠柳毒苷

Apoptosis; Others Apoptosis; Others
Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径,具有促进伤口愈合的潜力。
TN3270 (R)-3β-Hydroxy steroid sulfotransferase-IN-11

Others Others
(R)-3β-Hydroxy steroid sulfotransferase-IN-11 在生命科学相关研究中具有广泛的应用。
TMA0984 Cerevisterol

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Cerevisterol 是一种细胞毒性类固醇,提取于Agaricus blazei 子实体,对 DNA 聚合酶 α 的活性具有抑制作用。
T2207 Adrenosterone

肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Androgen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物,由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素,具有较弱的雄激素特性。它是一种膳食补充剂,能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。
T36857 Estrone sulfate sodium

雌酮3-硫酸钠,Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate

Endogenous Metabolite Metabolism
Estrone sulfate sodium (17β-Estrone 3-sulfate) 是一种主要的循环血浆雌激素,无生物活性,通过类固醇硫酸酯酶(STS) 转化为生物活性雌激素雌酮。
T1048 Estradiol

雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Estradiol (E2) 是一种天然的类固醇性激素,对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
T14001 11-Beta-hydroxyandrostenedione

4-雄烯-11β-醇-3,17-二酮,NSC-17102,4-Androsten-11β-ol-3,17-dione

Endogenous Metabolite Metabolism
11-Beta-hydroxyandrostenedione (NSC-17102) 是主要存在于肾上腺的类固醇,也是 11β-羟基类固醇脱氢酶同工酶抑制剂。随着 4-androstenedione 的提高,通过测量血浆中的11-Beta-hydroxyandrostenedione,能够区分高雄激素血症的肾上腺或卵巢起源。
TN3910 Ecdysone

Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
Ecdysone 是存在于昆虫和草药中的主要类固醇激素,可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
T3220 Euphorbiasteroid

Euphobiasteroid,Euphorbia factor L1,千金子甾醇

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
Euphorbiasteroid (Euphobiasteroid) 是续随子中的一种三环二萜,可抑制酪氨酸酶活性,增强AMPK 的磷酸化。它通过减少细胞内甘油三酯的积累来降低 3T3-L1 细胞的分化,具有抗癌、抗病毒、抗肥胖及多重耐药调节作用。
TN7130 Chlorogenin

Others Others
Chlorogenin 是一种源自 Agave americana 草本植物的天然类固醇。
T13500 3-O-Acetyl-20-Hydroxyecdysone

Others Others
3-O-Acetyl-20-Hydroxyecdysone 是分离自Cyanotis arachnoidea C.B.Clark 根中的类固醇。
T8043 5α-Cholestane

Endogenous Metabolite Metabolism
5α-Cholestane 属于胆甾烷类固醇类化合物。
T20302 Deoxycorticosterone

Desoxycorticosterone,去氧皮质酮,Desoxycorticosteronum,Desoxycortone

Endogenous Metabolite Metabolism
Deoxycorticosterone (Desoxycortone) 是由肾上腺产生的类固醇代谢物。 Deoxycorticosterone 是醛固酮前体,具有盐皮质激素活性。
TN1075 Adynerin

Others Others
Adynerin 是一种发现于夹竹桃中的天然类固醇。
T3130 Testosterone phenylpropionate

Testosterone hydrocinnamate,苯丙酸睾酮,Retandrol,Testosterone 17-phenylpropionate

Others Others
Testosterone phenylpropionate (Testosterone 17-phenylpropionate) 是一种长效雄激素。d3-Testosterone phenylpropionate 可用作内标物。
T2748 Cortodoxone

可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Cortodoxone (11-Desoxycortisol) 是糖皮质类固醇激素,能够氧化为皮质醇。
T73772 Estrone sulfate potassium

Endogenous Metabolite Metabolism
Estrone sulfate potassium 是一种雌激素酯和共轭物,是一种天然内源性类固醇。
T0856 Dehydroisoandrosterone 3-acetate

Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,醋酸去氢表雄酮,androstenolone acetate

Androgen Receptor Endocrinology/Hormones
Dehydroisoandrosterone 3-acetate (Prasterone acetate) 是一种雄性激素/雌性激素的前体物质,是一种由肾上腺皮质产生的主要 C19 类固醇,能够调节脊椎动物的攻击性行为。
T10048 17a-Hydroxypregnenolone

Endogenous Metabolite Metabolism
17a-Hydroxypregnenolone 是一种孕烷类固醇, 是形成脱氢表雄酮的激素原。17a-Hydroxypregnenolone 是一种神经调节剂。
T6S1842 Tenacissoside G

Tenacissimoside A,通关藤苷G

Others; P-gp Membrane transporter/Ion channel; Neuroscience; Others
Tenacissoside G 是一种 C21 甾体,来自于Marsdenia tenacissima茎部。它可逆转 P-糖蛋白过度表达的多药耐药癌细胞的多药耐药。
T7024 Qingyangshengenin

青阳参甙元,Qingyangshengenin A,Cynanchagenin

Others Others
Qingyangshengenin (Cynanchagenin) 是一种孕烷糖苷,是一种分离自Cychuchumot ophyllum(Asclepiadaceae) 的根中的 C21 类固醇糖苷配基。它具有抗癌作用。
T3033 Deoxycorticosterone acetate

醋酸去氧皮质酮,DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate,醋酸脱氧皮质酮

Glucocorticoid Receptor; Endogenous Metabolite; Adrenergic Receptor Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
Deoxycorticosterone acetate (Cortexone acetate) 是肾上腺产生的类固醇激素,具有盐皮质激素活性,并作为醛固酮的前体。
T12536 Pregnenolone monosulfate

3β-Hydroxy-5-pregnen-20-one monosulfate

NMDAR Neuroscience
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) 是一种强效神经类固醇,可正向调节 NMDA 记录,可用于研究神经分裂和抑郁症。
T2822 Ginsenoside Rb1

Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III

ATPase; Mitophagy; IRAK; NF-κB; Autophagy; HSV Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; NF-κB
Ginsenoside Rb1 (Gypenoside Ⅲ) 是中药人参的成分,可能具有抑制或阻止肿瘤生长的特性。
TC0019 Pregnenolone acetate

孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
Pregnenolone acetate 是一种强大的神经类固醇,是各种类固醇激素(包括类固醇酮)的主要前体。它作为大麻素 CB1 受体的信号特异性抑制剂,抑制由 CB1 受体介导的四氢大麻酚 (THC) 的作用。它可以保护大脑免受大麻中毒。
T3S0895 Spirostan-3-ol

剑麻皂苷元,Sarsaponin

Others Others
Spirostan-3-ol (Sarsaponin) 是 Sarsasapogenin 的立体异构体,是从植物材料中分离出来的类固醇糖苷,具有潜在的通过细胞凋亡的抗肿瘤活性。它可驱赶蜜蜂。
TN7099 antcin A

NOD Immunology/Inflammation; NF-κB
antcin A 是一种类固醇类植物化学物质,从珍贵的食用菌牛樟芝子实体中分离出来,具有很强的抗炎和抗肿瘤作用。
T5751 Tigogenin

Others Others
Tigogenin 是甾体皂甙元,普遍用于甾体类药物的合成。它能够阻碍小鼠骨髓基质细胞脂肪细胞分化,促使成骨细胞的分化。
T8040 Cholesterol myristate

胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate

Others; Potassium Channel; GABA Receptor; Endogenous Metabolite; AChR Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
Cholesterol myristate (Cholesteryl myristate) 是粗吻海龙中的一种类固醇,可与多种离子通道结合,例如nAChR、GABAA 受体和内向整流钾离子通道。
T7990 9-hydroxy-4-androstene-3,17-dione

Others Others
9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素,具有抗肿瘤活性,可以抑制多种癌症细胞的生长,包括乳腺癌、前列腺癌和肺癌细胞。
T74293 Allolithocholic acid

Others Others
Allolithocholic acid 是一种类固醇酸,在正常血清和粪便中可发现。该化合物促进脂肪与甾醇在肠道及肝脏的排泄、吸收与运输。
T2777 Ginsenoside Rg1

Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2

Apoptosis; Beta Amyloid; NF-κB Apoptosis; Neuroscience; NF-κB
Ginsenoside Rg1 (Panaxoside Rg1) 是人参的主要活性成分之一,可减少NF-κB 核易位。它改善认知功能受损,通过降低大脑Aβ水平来发挥作用。
T1429 17α-Hydroxyprogesterone

Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Others
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。
T2881 Crustecdysone

Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素

Others; Caspase; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome
Crustecdysone (Hydroxyecdysone) 是来源于露水草的一种蜕皮激素,可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone 的活性代谢物,通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬,在心血管系统中具有调节或保护作用。
T0851 Pregnenolone

3β-Hydroxy-5-pregnen-20-one,Arthenolone,孕烯醇酮

Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel; AChR; Autophagy Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
Pregnenolone (Arthenolone) 是一种由胆固醇合成的内源性类固醇激素,用于治疗阿尔茨海默病。它是大麻素 CB1受体的信号传导特异性抑制剂,抑制由 CB1受体介导的四氢大麻酚 的作用。它也是 TRPM3通道激活剂,也可弱激活 TRPM1通道。
T0948L Corticosterone

皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Corticosterone (Kendall's compound B) 是一种肾上腺皮质类固醇,有盐皮质激素和糖皮质激素的活性,具有口服活性。Corticosterone 参与体内能量、免疫反应和应激反应的调节。
T6654 Saponins

Sapogenins Glycosides,皂素,Saponin

Others Others
Saponins (Sapogenins Glycosides) 是一种苷类的化合物,多发现于多种植物中,可保护植物免受微生物和真菌的破坏。
T4878 Hecogenin

海柯吉宁,Hocogenin

Others; Antifungal Microbiology/Virology; Others
Hecogenin(Hocogenin),一种从Agave sisalana提取的甾体皂苷,作为人类UDP-glucuronosyltransferases的特异性抑制剂。它具有广泛的药理活性,包括抗炎、抗真菌和胃保护作用[1]。
T5574 Guggulsterone

Guggulsterone E&Z,香胶甾酮

Apoptosis; FXR; Akt; Caspase; JNK; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Guggulsterone (Guggulsterone E&Z) E&Z 是来自Commiphora wightii 树中树胶脂的植物甾醇。 它通过下调抗细胞凋亡基因产物 ,调节细胞周期蛋白,激活caspases,JNK,抑制Akt,抑制多种肿瘤细胞的生长并诱导细胞凋亡。它是法尼醇 X 受体拮抗剂,可降低 CDCA 诱导的 FXR 活化。
T0478 Progesterone

孕酮,Pregn-4-ene-3,20-dione

Estrogen/progestogen Receptor; Progesterone Receptor; Opioid Receptor; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience; Others
Progesterone (Pregn-4-ene-3,20-dione) 是类固醇激素,能够调节月经周期。
T19124 3-​Oxocholic acid

3-Ketocholic acid

Endogenous Metabolite Metabolism
3-​Oxocholic acid(3-Ketocholic acid) 是胆汁酸的代谢产物,也是产气荚膜梭菌在肠道中由胆汁降解的主要产物。33-​Oxocholic acid 是一种主要存在于哺乳动物的胆汁中类固醇酸。
T2733 Sarsasapogenin

Parigenin,知母皂苷元,Sarsagenin

Apoptosis; NF-κB; Endogenous Metabolite Apoptosis; Metabolism; NF-κB
Sarsasapogenin (Parigenin) 是一种甾体皂苷元,从中草药知母中分离到,具有抗糖尿病、抗氧化、抗癌、抗炎等作用。
T1009 Estrone

Oestrone,雌酮,Fluoroethyl,Aquacrine

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Estrone (Aquacrine) 是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
T4717 25-Hydroxycholesterol

25-羟基胆固醇,25-羟基胆甾醇

Others; Endogenous Metabolite; HMG-CoA Reductase Metabolism; Others
25-Hydroxycholesterol 是胆固醇的代谢产物,由巨噬细胞响应 Toll 样受体激活而分泌。它有效抑制 B 细胞产生 IgA,EC50约为 65 nM。
T3674 Hydroxysafflor yellow A

藏红花,羟基红花黄色素A,HSYA,Safflomin A

TGF-beta/Smad Stem Cells
Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物,从中药红花中分离得到,具有抗癌作用。
T4A2458 Resibufogenin

酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基,蟾力苏

Others Others
Resibufogenin (Bufogenin) 是华蟾素的成分之一,表现出抑制氧化应激及肿瘤再生的活性。
T5234 Glycoursodeoxycholic acid

Ursodeoxycholylglycine,甘氨熊胆酸,GUDCA

Others; Endogenous Metabolite Metabolism; Others
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) 是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物,是熊去氧胆酸的代谢物。
T6480 D-Pantothenic acid

vitamin B5,pantothenate,D-泛酸

Others Others
D-Pantothenic acid (vitamin B5) 是必需的微量营养素,是辅酶 A 的前体,在很多生物过程中发挥关键作用,如调节碳水化合物,脂质,蛋白和核酸代谢。
TN2254 Taccalonolide A

根薯酮内酯A,根薯酮内酯 A

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Taccalonolide A 是从水田七根茎中分离得到的一种类固醇,具有细胞毒性和抗疟活性。它在体外对过表达 p 糖蛋白、多药耐药蛋白 7 细胞系有抑制作用,抑制 SK-OV-3 细胞生长的 IC50值为 622 nM。它是微管稳定剂,能引起 G2-M 期滞留、Bcl-2 磷酸化,并引发细胞凋亡。
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天然产物

Nandrolone phenylpropionate
Cat.No: T8709
Synonym: Nandrolone phenpropionate,苯丙酸诺龙
Target: Androgen Receptor
Periplocin
Cat.No: T5S1982
Synonym: Periplocoside,杠柳毒苷
Target: Apoptosis, Others
(R)-3β-Hydroxy steroid sulfotransferase-IN-11
Cat.No: TN3270
Synonym:
Target: Others
Cerevisterol
Cat.No: TMA0984
Synonym:
Target: DNA/RNA Synthesis
Adrenosterone
Cat.No: T2207
Synonym: 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G
Target: Androgen Receptor, Endogenous Metabolite
Estrone sulfate sodium
Cat.No: T36857
Synonym: 雌酮3-硫酸钠,Estrone 3-sulfate (sodium salt),17β-Estrone 3-sulfate
Target: Endogenous Metabolite
Estradiol
Cat.No: T1048
Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
11-Beta-hydroxyandrostenedione
Cat.No: T14001
Synonym: 4-雄烯-11β-醇-3,17-二酮,NSC-17102,4-Androsten-11β-ol-3,17-dione
Target: Endogenous Metabolite
Ecdysone
Cat.No: TN3910
Synonym:
Target: Apoptosis, ATPase, Glucocorticoid Receptor, Potassium Channel, Sodium Channel, Endogenous Metabolite, Autophagy
Euphorbiasteroid
Cat.No: T3220
Synonym: Euphobiasteroid,Euphorbia factor L1,千金子甾醇
Target: Others, AMPK
Chlorogenin
Cat.No: TN7130
Synonym:
Target: Others
3-O-Acetyl-20-Hydroxyecdysone
Cat.No: T13500
Synonym:
Target: Others
5α-Cholestane
Cat.No: T8043
Synonym:
Target: Endogenous Metabolite
Deoxycorticosterone
Cat.No: T20302
Synonym: Desoxycorticosterone,去氧皮质酮,Desoxycorticosteronum,Desoxycortone
Target: Endogenous Metabolite
Adynerin
Cat.No: TN1075
Synonym:
Target: Others
Testosterone phenylpropionate
Cat.No: T3130
Synonym: Testosterone hydrocinnamate,苯丙酸睾酮,Retandrol,Testosterone 17-phenylpropionate
Target: Others
Cortodoxone
Cat.No: T2748
Synonym: 可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol
Target: Glucocorticoid Receptor, Endogenous Metabolite
Estrone sulfate potassium
Cat.No: T73772
Synonym:
Target: Endogenous Metabolite
Dehydroisoandrosterone 3-acetate
Cat.No: T0856
Synonym: Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,醋酸去氢表雄酮,androstenolone acetate
Target: Androgen Receptor
17a-Hydroxypregnenolone
Cat.No: T10048
Synonym:
Target: Endogenous Metabolite
Tenacissoside G
Cat.No: T6S1842
Synonym: Tenacissimoside A,通关藤苷G
Target: Others, P-gp
Qingyangshengenin
Cat.No: T7024
Synonym: 青阳参甙元,Qingyangshengenin A,Cynanchagenin
Target: Others
Deoxycorticosterone acetate
Cat.No: T3033
Synonym: 醋酸去氧皮质酮,DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate,醋酸脱氧皮质酮
Target: Glucocorticoid Receptor, Endogenous Metabolite, Adrenergic Receptor
Pregnenolone monosulfate
Cat.No: T12536
Synonym: 3β-Hydroxy-5-pregnen-20-one monosulfate
Target: NMDAR
Ginsenoside Rb1
Cat.No: T2822
Synonym: Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III
Target: ATPase, Mitophagy, IRAK, NF-κB, Autophagy, HSV
Pregnenolone acetate
Cat.No: TC0019
Synonym: 孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate
Target: Cannabinoid Receptor, Endogenous Metabolite
Spirostan-3-ol
Cat.No: T3S0895
Synonym: 剑麻皂苷元,Sarsaponin
Target: Others
antcin A
Cat.No: TN7099
Synonym:
Target: NOD
Tigogenin
Cat.No: T5751
Synonym:
Target: Others
Cholesterol myristate
Cat.No: T8040
Synonym: 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate
Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR
9-hydroxy-4-androstene-3,17-dione
Cat.No: T7990
Synonym:
Target: Others
Allolithocholic acid
Cat.No: T74293
Synonym:
Target: Others
Ginsenoside Rg1
Cat.No: T2777
Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2
Target: Apoptosis, Beta Amyloid, NF-κB
17α-Hydroxyprogesterone
Cat.No: T1429
Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite
Crustecdysone
Cat.No: T2881
Synonym: Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素
Target: Others, Caspase, Endogenous Metabolite, Autophagy
Pregnenolone
Cat.No: T0851
Synonym: 3β-Hydroxy-5-pregnen-20-one,Arthenolone,孕烯醇酮
Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel, AChR, Autophagy
Corticosterone
Cat.No: T0948L
Synonym: 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)
Target: Glucocorticoid Receptor, Endogenous Metabolite
Saponins
Cat.No: T6654
Synonym: Sapogenins Glycosides,皂素,Saponin
Target: Others
Hecogenin
Cat.No: T4878
Synonym: 海柯吉宁,Hocogenin
Target: Others, Antifungal
Guggulsterone
Cat.No: T5574
Synonym: Guggulsterone E&Z,香胶甾酮
Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy
Progesterone
Cat.No: T0478
Synonym: 孕酮,Pregn-4-ene-3,20-dione
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Opioid Receptor, Endogenous Metabolite
3-​Oxocholic acid
Cat.No: T19124
Synonym: 3-Ketocholic acid
Target: Endogenous Metabolite
Sarsasapogenin
Cat.No: T2733
Synonym: Parigenin,知母皂苷元,Sarsagenin
Target: Apoptosis, NF-κB, Endogenous Metabolite
Estrone
Cat.No: T1009
Synonym: Oestrone,雌酮,Fluoroethyl,Aquacrine
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
25-Hydroxycholesterol
Cat.No: T4717
Synonym: 25-羟基胆固醇,25-羟基胆甾醇
Target: Others, Endogenous Metabolite, HMG-CoA Reductase
Hydroxysafflor yellow A
Cat.No: T3674
Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A
Target: TGF-beta/Smad
Resibufogenin
Cat.No: T4A2458
Synonym: 酯蟾毒配基,Bufogenin,Recibufogenin,酯蟾毒配基,蟾力苏
Target: Others
Glycoursodeoxycholic acid
Cat.No: T5234
Synonym: Ursodeoxycholylglycine,甘氨熊胆酸,GUDCA
Target: Others, Endogenous Metabolite
D-Pantothenic acid
Cat.No: T6480
Synonym: vitamin B5,pantothenate,D-泛酸
Target: Others
Taccalonolide A
Cat.No: TN2254
Synonym: 根薯酮内酯A,根薯酮内酯 A
Target: Apoptosis, Microtubule Associated
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Cat. No. Product Name Species Expression System
TMPH-02996 KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)

3-oxosteroid 1-dehydrogenase,3-keto-Delta(4)-st...

Mycolicibacterium smegmatis E. coli
Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to. KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 68.9 kDa and the accession number is A0R4S9.
TMPH-02139 CYP17A1 Protein, Human, Recombinant (GST)

Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17,S17AH,Cytochrome ...

Human E. coli
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow...
TMPH-00851 HSD3B1 Protein, Human, Recombinant (His & Myc)

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-iso...

Human E. coli
HSD3B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is P14060.
TMPH-02140 CYP21A2 Protein, Human, Recombinant (E. coli, His)

Cytochrome P-450c21,Cytochrome P450-C21B,CYP21,21-OHase,Cyto...

Human E. coli
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02141 CYP21A2 Protein, Human, Recombinant (His)

Cytochrome P450 21,CYP21A2,Cytochrome P450-C21B,Cytochrome P...

Human P. pastoris (Yeast)
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02142 ERR1 Protein, Human, Recombinant (GST)

Steroid hormone receptor ERR1,Estrogen receptor-lik...

Human E. coli
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
TMPH-01793 NR1I2 Protein, Human, Recombinant (His & Myc & SUMO)

Orphan nuclear receptor PXR,NR1I2,Steroid and xenob...

Human E. coli
NR1I2 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 69.8 kDa and the accession number is O75469.
TMPH-02143 NR5A1 Protein, Human, Recombinant (His)

Adrenal 4-binding protein,NR5A1,Steroidogenic facto...

Human E. coli
Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cA...
TMPJ-00207 AKR1C2 Protein, Human, Recombinant

3-Alpha-HSD3,Chlordecone Reductase Homolog HAKRD,2-Diol Dehy...

Human E. coli
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
TMPH-03654 Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-iso...

VACV E. coli
Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response. Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPH-00220 Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)

Hepato-ferredoxin,FDX1,Ferredoxin-1,Adrenodoxin, mitochondri...

Bovine E. coli
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Adrenodoxin, mitochondrial Protein, Bov...
TMPH-00199 Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO)

Allergen Bet v I-A,Major pollen allergen Bet v 1-A,BETVI,BET...

Betula pendula E. coli
May be a general steroid carrier protein. Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.4 kDa and the accession number is P15494.
TMPH-01811 OR7D4 Protein, Human, Recombinant (His & KSI)

Olfactory receptor 7D4,Odorant receptor family subfamily D m...

Human E. coli
Odorant receptor. Selectively activated by androstenone and the related odorous steroid androstadienone. OR7D4 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.5 kDa and the accession number is Q8NG98.
TMPH-01747 FDXR Protein, Human, Recombinant (His & SUMO)

Ferredoxin--NADP(+) reductase,NADPH:adrenodoxin oxidoreducta...

Human E. coli
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. FDXR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 61.6 kDa and the accession number is P22570.
TMPH-00287 Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)

Ferredoxin--NADP(+) reductase,ADXR,NADPH:adrenodoxin oxidore...

Bovine E. coli
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.8 kDa and the accession number is ...
TMPJ-01076 FKBP4 Protein, Human, Recombinant (His)

FKBP4,HSP-binding immunophilin,immunophilin FKBP52,FK506-bin...

Human E. coli
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
TMPH-00288 Adrenodoxin reductase Protein, Bovine, Recombinant (His)

Ferredoxin reductase,Adrenodoxin reductase,Ferredoxin--NADP(...

Bovine P. pastoris (Yeast)
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P08165.
TMPY-00481 AKR1C4 Protein, Human, Recombinant (His)

aldo-keto reductase family 1, member C4,3-alpha-HSD,DD4,CHDR...

Human E. coli
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, an...
TMPH-03128 TSPO Protein, Pig, Recombinant (His & Myc & SUMO)

TSPO,Peripheral-type benzodiazepine receptor,Translocator pr...

Sus scrofa (Pig) E. coli
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. TSPO Protein, Pig, Recombinant (His & Myc & SUMO) is expressed in E. coli e...
TMPH-01303 HSD17B11 Protein, Human, Recombinant (His & Myc)

Estradiol 17-beta-dehydrogenase 11,HSD17B11,Retinal short-ch...

Human E. coli
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. HSD17B11 Prot...
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

Apolipoprotein A-I,APOA1,Apo-AI,ApoA-I

Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including T...
TMPY-03991 DBI Protein, Human, Recombinant (His)

diazepam binding inhibitor (GABA receptor modulator, acyl-Co...

Human E. coli
The diazepam binding inhibitor (DBI), alternatively known as the acyl-CoA binding protein (ACBP), is involved in multiple biological actions. The polypeptide binds to the peripheral, or mitochondrial, benzodiazepine receptor and facilitates transport of cholesterol to the inner membrane to stimulate steroid synthesis. Through this action, DBI indirectly modulates gamma-aminobutyric acid (GABA)-mediated inhibitory neurotransmission. DBI can be postulated as a candidate gene for psychiatric phenot...
TMPY-00867 Kallikrein 13/KLK13 Protein, Human, Recombinant (His)

KLKL4,kallikrein-related peptidase 13,KLK-L4

Human HEK293 Cells
Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evide...

重组蛋白

KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)
Cat.No: TMPH-02996
Species: Mycolicibacterium smegmatis
Expression System: E. coli
CYP17A1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02139
Species: Human
Expression System: E. coli
HSD3B1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00851
Species: Human
Expression System: E. coli
CYP21A2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02140
Species: Human
Expression System: E. coli
CYP21A2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02141
Species: Human
Expression System: P. pastoris (Yeast)
ERR1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02142
Species: Human
Expression System: E. coli
NR1I2 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01793
Species: Human
Expression System: E. coli
NR5A1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02143
Species: Human
Expression System: E. coli
AKR1C2 Protein, Human, Recombinant
Cat.No: TMPJ-00207
Species: Human
Expression System: E. coli
Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)
Cat.No: TMPH-03654
Species: VACV
Expression System: E. coli
Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00220
Species: Bovine
Expression System: E. coli
Bet v 1-A Protein, Betula pendula, Recombinant (His & SUMO)
Cat.No: TMPH-00199
Species: Betula pendula
Expression System: E. coli
OR7D4 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01811
Species: Human
Expression System: E. coli
FDXR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01747
Species: Human
Expression System: E. coli
Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)
Cat.No: TMPH-00287
Species: Bovine
Expression System: E. coli
FKBP4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01076
Species: Human
Expression System: E. coli
Adrenodoxin reductase Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00288
Species: Bovine
Expression System: P. pastoris (Yeast)
AKR1C4 Protein, Human, Recombinant (His)
Cat.No: TMPY-00481
Species: Human
Expression System: E. coli
TSPO Protein, Pig, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03128
Species: Sus scrofa (Pig)
Expression System: E. coli
HSD17B11 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01303
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
Cat.No: TMPJ-00158
Species: Human
Expression System: E. coli
DBI Protein, Human, Recombinant (His)
Cat.No: TMPY-03991
Species: Human
Expression System: E. coli
Kallikrein 13/KLK13 Protein, Human, Recombinant (His)
Cat.No: TMPY-00867
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T19416 Medroxyprogesterone acetate D3

MPA D3,Medroxyprogesterone 17-acetate D3

Others Others
Medroxyprogesterone acetate D3 is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.
TMID-0008 Boldenone-d3

Boldenone-d3 是 Boldenone 的氘代化合物。Boldenone 的 CAS 号为 846-48-0。Boldenone 是一种为兽医开发的合成代谢类固醇。
TMID-0109 11-Deoxycorticosterone-d8

11-Deoxycorticosterone-d8 是 11-Deoxycorticosterone 的氘代化合物。11-Deoxycorticosterone 的 CAS 号为 64-85-7。Deoxycorticosterone 是由肾上腺产生的类固醇代谢物。 Deoxycorticosterone 是醛固酮前体,具有盐皮质激素活性。
TMID-0115 Dehydroepiandrosterone-2,2,3,4,4,6-d6

DHEA-d6

Dehydroepiandrosterone-2,2,3,4,4,6-d6 是 Dehydroepiandrosterone 的氘代化合物。Dehydroepiandrosterone 的 CAS 号为 53-43-0。Dehydroepiandrosterone 是一种类固醇激素。它通过多种信号传导途径介导其作用,并通过转化成雄激素和雌激素衍生物(例如,雄激素,雌激素,7α和7β DHEA (Prasterone),以及7α和7β表雄甾酮衍生物)在特异性受体上起作用。
TMID-0111 11-Deoxycortisol-2,2,4,6,6-d5

11-Deoxycortisol-2,2,4,6,6-d5 是 11-Deoxycortisol 的氘代化合物。11-Deoxycortisol 的 CAS 号为 152-58-9。Cortodoxone是糖皮质类固醇激素,能够氧化为皮质醇。
TMID-0147 17a-Hydroxypregnenolone-d3

17a-Hydroxypregnenolone-d3 是 17a-Hydroxypregnenolone 的氘代化合物。17a-Hydroxypregnenolone 的 CAS 号为 387-79-1。17a-Hydroxypregnenolone 是一种孕烷类固醇, 是形成脱氢表雄酮的激素原。17a-Hydroxypregnenolone 是一种神经调节剂。
TMID-0148 Nandrolone 17-propionate-d3

Nandrolone 17-propionate-d3 是 Nandrolone 17-propionate 的氘代化合物。Nandrolone 17-propionate 的 CAS 号为 7207-92-3。Nandrolone propionate 是合成代谢类固醇,主要由雄激素和保氮剂组成,具有作用时间相对较长的特点。
TMID-0112 21-Deoxycortisol-d8

21-Deoxycortisol-d8 是 21-Deoxycortisol 的氘代化合物。21-Deoxycortisol 的 CAS 号为 641-77-0。
TMID-0137 Pregnenolone-d4

Pregnenolone-d4 是 Pregnenolone 的氘代化合物。Pregnenolone 的 CAS 号为 145-13-1。Pregnenolone 是一种由胆固醇合成的内源性类固醇激素,用于治疗阿尔茨海默病。它是大麻素CB1受体的信号传导特异性抑制剂,抑制由CB1受体介导的四氢大麻酚 的作用。它也是TRPM3通道激活剂,也可弱激活TRPM1通道。
TMIH-0089 Androstenedione-d7

Androstenedione-d7 是 Androstenedione 的氘代化合物。Androstenedione 的 CAS 号为 560-62-3。9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素,具有抗肿瘤活性,可以抑制多种癌症细胞的生长,包括乳腺癌、前列腺癌和肺癌细胞。
TMIJ-0313 Estrone-d2

Estrone-d2 是 Estrone 的氘代化合物。Estrone 的 CAS 号为 53-16-7。Aquacrine是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
TMIJ-0255 Estrone-d4

Estriol EP Impurity B-d4

Estrone-d4 是 Estrone 的氘代化合物。Estrone 的 CAS 号为 53-16-7。Aquacrine是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
TMIH-0257 Glycoursodeoxycholic Acid-d4

Glycoursodeoxycholic Acid-d4 是 Glycoursodeoxycholic Acid 的氘代化合物。Glycoursodeoxycholic Acid 的 CAS 号为 64480-66-6。Glycoursodeoxycholic acid 是一种酰基甘氨酸和胆汁酸-甘氨酸缀合物,是熊去氧胆酸的代谢物。
TMID-0142 4-Androsten-11β-ol-3,17-dione-d7

4-Androsten-11β-ol-3,17-dione-d7 是 4-Androsten-11β-ol-3,17-dione 的氘代化合物。4-Androsten-11β-ol-3,17-dione 的 CAS 号为 382-44-5。11-Beta-hydroxyandrostenedione 是主要存在于肾上腺的类固醇,也是 11β-羟基类固醇脱氢酶同工酶抑制剂。随着 4-androstenedione 的提高,通过测量血浆中的11-Beta-hydroxyandrostenedione,能够区分高雄激素血症的肾上腺或卵巢起源。

同位素标记化合物

Medroxyprogesterone acetate D3
Cat.No: T19416
Synonym: MPA D3,Medroxyprogesterone 17-acetate D3
Target: Others
Boldenone-d3
Cat.No: TMID-0008
Synonym:
Target:
11-Deoxycorticosterone-d8
Cat.No: TMID-0109
Synonym:
Target:
Dehydroepiandrosterone-2,2,3,4,4,6-d6
Cat.No: TMID-0115
Synonym: DHEA-d6
Target:
11-Deoxycortisol-2,2,4,6,6-d5
Cat.No: TMID-0111
Synonym:
Target:
17a-Hydroxypregnenolone-d3
Cat.No: TMID-0147
Synonym:
Target:
Nandrolone 17-propionate-d3
Cat.No: TMID-0148
Synonym:
Target:
21-Deoxycortisol-d8
Cat.No: TMID-0112
Synonym:
Target:
Pregnenolone-d4
Cat.No: TMID-0137
Synonym:
Target:
Androstenedione-d7
Cat.No: TMIH-0089
Synonym:
Target:
Estrone-d2
Cat.No: TMIJ-0313
Synonym:
Target:
Estrone-d4
Cat.No: TMIJ-0255
Synonym: Estriol EP Impurity B-d4
Target:
Glycoursodeoxycholic Acid-d4
Cat.No: TMIH-0257
Synonym:
Target:
4-Androsten-11β-ol-3,17-dione-d7
Cat.No: TMID-0142
Synonym:
Target:
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