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Search Results for " ret "

Targets Recommended: c-RET Retinoid Receptor Beta-Secretase Gamma-secretase c-RET

289

抑制剂 & 化合物

59

天然产物

1

化合物库

52

重组蛋白

14

同位素标记化合物

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Cat. No.	Product Name
L9700	内质网应激化合物库		193 compounds
	193 个内质网应激相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

内质网应激化合物库

Cat.No: L9700

Compounds: 193

Cat. No.	Product Name	Target	Signaling Pathways
T9673	RET-IN-3	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	RET-IN-3 是一种具有选择性和高效性的 RETV804M 激酶抑制剂，具有潜在抗癌活性,可用于研究非小细胞肺癌。
T8467	RET V804M-IN-1 RETV804M kinase inhibitor,LUN09945	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	RET V804M-IN-1 (RETV804M kinase inhibitor) 是一种 wt-RET 选择性的RETV804M 激酶抑制剂，其IC50=20 nM。
T69644	DUN73423 RET-IN-21	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	DUN73423 (RET-IN-21) 是一种有效的酪氨酸激酶 (RET) 抑制剂，具有抗肿瘤活性，可用于研究癌症。
T40097	RET-IN-4	Others	Others
	RET-IN-4 is a highly effective and specific RET inhibitor that can be administered orally. It demonstrates remarkable potency, with IC50 values of 1.29 nM, 1.97 nM, and 0.99 nM for inhibiting RET variants including RET (WT), RET (V804M), and RET (M918T), respectively. Moreover, RET-IN-4 exhibits superior selectivity towards kinases JAK2 (IC50 of 4.4 nM) and FLT3 (IC50 of 30.8 nM). Additionally, RET-IN-4 possesses pronounced anticancer properties.
T16735	RET-IN-1	Others	Others
	RET-IN-1 is a RET kinase inhibitor (IC50s: 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively).
T8222	Selpercatinib LOXO-292	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	Selpercatinib (LOXO-292) 是 RET 激酶抑制剂，抑制 RET (WT)、RET (V804M) 、RET (G810R)的 IC50分别为 14.0 nM、24.1 nM、530.7 nM，具有抗肿瘤活性。
T73309	RET-IN-20	Others	Others
	RET-IN-20 是一种有效的RET 抑制剂，IC50值为 13.7 nM。RET-IN-20 降低 p-Ret、p-Shc 蛋白的表达。RET-IN-20 诱导细胞凋亡 (apoptosis)。RET-IN-20 具有抗增殖和抗肿瘤活性。
T78683	RET-IN-22	Others	Others
	RET-IN-22（compound 17b）是一种有效且选择性的口服活性RET抑制剂，其对野生型RET和RET-V804M的IC50分别为20.9 nM与18.3 nM。该化合物展现出对多数激酶，特别是EGFR和VEGFR2的高度选择性，表现出抗癌活性。
T63358	RET-IN-15	Others	Others
	RET-IN-15 是转染期间重排激酶 (RET) 的抑制剂，能够用于癌症的研究。
T79099	RET-IN-23	Others	Others
	RET-IN-23（化合物17）是一种有效的口服RET抑制剂，其IC50值对应RET-WT为1.32 nM、RET-CCDC6为2.50 nM、RET-V804L为6.54 nM、RET-V804M为1.03 nM及RET-M918T为1.47 nM。该化合物展现出了明显的抗肿瘤活性。
T63772	RET-IN-5	Others	Others
	RET-IN-5 是 RET 的有效抑制剂 (IC50: 4.57 nM)。
T79163	RET-IN-24	Others	Others
	RET-IN-24（Compound 26）为选择性RET酪氨酸激酶抑制剂，具抗肿瘤活性。
T79726	RET-IN-25	Others	Others
	RET-IN-25（化合物6b）是一种具有抗癌活性的RET激酶抑制剂。该化合物能够抑制甲状腺髓样癌（MTC），在TT(C634R) MTC细胞系中的IC50值分别为3.6 μM（3天）和3.0 μM（6天）。
T64103	RET-IN-12	Others	Others
	RET-IN-12 是一种 RET 抑制剂，能够作用于 RET(WT) (IC50: 0.3 nM) 和 RET(V804M) (IC50: 1 nM)。
T63468	RET-IN-14	Others	Others
	RET-IN-14 是 RET 的有效抑制剂，能够作用于 RET (WT) (IC50<0.51 nM)、RET (G810R) (IC50: 9.3 nM)、RET (V804M) (IC50: 1.3 nM)、BTK (C481S) (IC50: 9.2 nM) 和 BTK (C481S) (IC50: 15 nM)。RET-IN-14 表现出潜力进行肿瘤的研究。
T63837	RET-IN-19	Others	Others
	RET-IN-19 是 RET 的有效抑制剂，能够作用于 RET-wt (IC50: 6.8 nM) 和 RET V804M (IC50: 13.51 nM)，表现出抗癌效果。RET-IN-19 能够用于研究非小细胞肺癌 (NSCLC)。
T63782	RET-IN-10	Others	Others
	RET-IN-10 是一种 RET 的有效抑制剂。其中 RET 功能缺失突变会造成先天性巨结肠，而其功能突变获得与多种人类肿瘤有关。RET-IN-10 对癌症疾病表现出研究潜力。
T63249	RET-IN-6	Others	Others
	RET-IN-6 是 RET 的有效抑制剂(IC50: 4.57 nM)。
T63877	RET-IN-17	Others	Others
	RET-IN-17 是 RET 的有效抑制剂。RET-IN-17 具有潜力进行与 IBS 和其他胃肠道疾病相关的疼痛以及具有组成性 RET 激酶活性的癌症的研究。
T62877	RET-IN-7	Others	Others
	RET-IN-7 在体外显示出强大的 RET 激酶抑制作用，在体内对 RET 驱动的肿瘤异种移植物具有强大的疗效。
T63230	RET-IN-8	Others	Others
	RET-IN-8 是转染期间重排激酶 (RET) 的抑制剂，能够用于癌症的研究。
T73256	RET-IN-16	Others	Others
	RET-IN-16 是一种有效且具有选择性的RET 抑制剂，对RET(WT)，RET(M918T)，RET(V804L)，RET(V804M)，RET-CCDC6和RET-KIF5B 的IC50分别为 3.98 nM，8.42 nM，15.05 nM，7.86 nM，5.43 nM 和 8.86 nM。RET-IN-16 具有抗癌作用。
T73248	RET-IN-13	Others	Others
	RET-IN-13 是一种喹啉化合物，一种有效的 RET 抑制剂，对 RET(WT) 和 RET(V804M) 的 IC50分别为 0.5 nM 和 0.9 nM。RET-IN-13 具有用于与RET 异常激活相关的肿瘤或肠道疾病研究的潜力。
T63583	RET-IN-11	Others	Others
	RET-IN-11 是有效的、选择性的 RET 抑制剂，能够作用于 RET (IC50: 6.20 nM) 和 RETV804M (IC50: 18.68 nM)。RET-IN-11 能够诱导细胞凋亡 (apoptosis)。RET-IN-11 在 LC-2/ad 细胞中表现出抗增殖和迁移效果。
T81296	RET-IN-26	Others	Others
	RET-IN-26（化合物D5）是一种RET kinase抑制剂，其IC50值为0.33 μM。
T63183	RET-IN-9	Others	Others
	RET-IN-9 是一种 RET 的有效抑制剂。其中 RET 激酶是一种单通道跨膜受体酪氨酸激酶，在肾脏和肠神经系统的发育以及维持神经、内分泌、造血和男性生殖系统的体内平衡中发挥着重要作用。RET-IN-9 具有潜力进行 RET 相关疾病的研究（包括非小细胞肺癌和甲状腺髓样癌）。
T12598	Pz-1	VEGFR; c-RET	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Pz-1 是 VEGFR2 和 RET 酪氨酸激酶的抑制剂，可阻断 RET 刺激生长所需的血液供应。
T10624	BT-13	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	BT-13 是一种胶质细胞源性神经营养因子 (GDNF) 受体 RET 的选择性激动剂，独立于 GDNF 配体发挥作用，能够促进体外感觉神经元神经突生长，减少大鼠神经病变的发生。
T16923	SPP-86	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	SPP-86 是有效的、选择性的RET 酪氨酸激酶抑制剂，其IC50=8 nM。它能够抑制 MCF7 细胞中 RET 诱导激活的 PI3K/Akt 和 MAPK 信号通路，也能抑制 RET 诱导的 ERα 磷酸化。
TQ0277	Pralsetinib 普拉替尼,Blu667	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	Pralsetinib (Blu667) 是高效的、选择性的RET 抑制剂。它能够抑制 WT RET (IC50:0.4 nM)，RET 突变体 V804L (IC50:0.3 nM)，V804M (IC50:0.4 nM)，M918T (IC50:0.4 nM) 和 CCDC6-RET (IC50:0.4 nM) 的融合。
T67733	BT44	Others	Others
	BT44是一种新的、第二代神经胶质细胞系衍生的神经营养因子模拟物，具有改善的生物活性，是治疗神经退行性疾病的先导化合物。
T4301	AD80	Raf; c-RET; Src; S6 Kinase	Angiogenesis; Apoptosis; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	AD80 是多激酶抑制剂，可抑制 RET、RAF、SRC 和 S6K，并大大降低 mTOR 活性。
T2282	RPI-1	Others; Phospholipase; c-Met/HGFR; c-RET	Apoptosis; Metabolism; Others; Tyrosine Kinase/Adaptors
	RPI1 是特异性的、口服具有活力的 2-吲哚啉酮Ret 酪氨酸激酶抑制剂，具有抗肿瘤作用。它能够抑制人甲状腺髓样癌 TT 细胞增殖、Ret 酪氨酸磷酸化、Ret 蛋白表达及 PLCgamma、ERKs 和 AKT 的活化。
T5491	GSK3179106	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	GSK3179106 是选择性的、具有口服活性的RET 激酶抑制剂，对人和大鼠 RET 的 IC50 分别为 0.4 nM 和 0.2 nM。它能够减轻炎症后和应激引起的内脏超敏反应，对肠易激综合征具有潜在的应用价值。
T7418	BBT594 NVP-BBT594	c-RET	Apoptosis; Tyrosine Kinase/Adaptors
	BBT594 (NVP-BBT594) 是受体酪氨酸激酶 RET 抑制剂，常用于研究癌症。
T3065	TG101209	Apoptosis; FLT; c-RET; JAK; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	TG101209 是一种选择性有效的 JAK2抑制剂，IC50值为 6 nM。它能抑制 Flt3和RET 的活性，IC50值分别为 25 nM 和 17 nM。
T22349	JNJ-38158471 CS-2660	VEGFR; c-RET; c-Kit	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	JNJ-38158471 (CS-2660) 是一种耐受性好的，有口服活性的、高效的、选择性的 VEGFR-2抑制剂 (IC50:40 nM)，还能抑制 Ret (IC50:180 nM) 和 Kit (IC50:500 nM)。
T1995	Fedratinib TG-101348,SAR 302503	Apoptosis; FLT; c-RET; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Fedratinib (TG-101348) 是一种 JAK2 抑制剂，具有选择性、ATP 竞争性和具有口服活性，抑制 JAK2 和 JAK2V617F 激酶 (IC50=3 nM)。Fedratinib 可诱导肿瘤细胞凋亡，并可用于骨髓增生性疾病的研究。
T1792L	Regorafenib monohydrate	Raf; VEGFR; c-RET; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
	Regorafenib monohydrate 是一种新型口服多激酶抑制剂，对VEGFR1/2/3、PDGFRβ、Kit、RET 和Raf-1的IC50分别为 13、4.2、46、22、7、1.5 和 2.5 nM。
T6920	ON123300	FGFR; c-RET; JAK; CDK; PDGFR; Src; AMPK	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	ON123300 是一种可透过血脑屏障的多激酶抑制剂，作用于 CDK4、CDK6、Ark5、PDGFRβ、FGFR1、RET 和 Fyn，IC50值为3.9、9.82、5、26、26、9.2和11 nM。它在脑肿瘤中抑制 Akt 磷酸化及激活 Erk。
T2032	WHI-P180 Janex 3	EGFR; VEGFR; c-RET; CDK	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	WHI-P180 (Janex 3) 是 EGFR 和 Cdk2 抑制剂，IC50 分别为 4.0 和 1.0 μM。
T8402	Regorafenib Hydrochloride 瑞戈非尼盐酸盐,BAY73-4506 hydrochloride	Raf; VEGFR; c-RET; PDGFR; Autophagy	Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
	Regorafenib Hydrochloride (BAY73-4506 hydrochloride) 是一种新型口服多激酶抑制剂，可抑制血管生成、基质和致癌受体酪氨酸激酶，具有强大的临床前抗肿瘤活性。它靶向作用于 VEGFR1/2/3、PDGFRβ、Kit、RET 和 Raf-1，IC50值分别为 13/4.2/46、22、7、1.5 和 2.5 nM。
T0520	Lenvatinib 仑伐替尼,E7080	VEGFR; FGFR; c-RET; PDGFR; c-Kit	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Lenvatinib (E7080) 是一种多靶点受体酪氨酸激酶抑制剂，抑制 VEGFR1-3、FGFR1-4、KIT、PDGFR 和 RET 等，具有口服活性。Lenvatinib 对 VEGFR2 和 VEGFR3 的抑制活性最强 (IC50=4/5.2 nM)。Lenvatinib 具有强效抗肿瘤活性。
TD0081	EDANS EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],EDANS酸,1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht	Others	Others
	EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) 是新型的淬灭荧光底物 (fluorogenic substrate)，可利用共振能量转移，分析逆转录病毒蛋白酶。
T4053	AST 487 NVP-AST 487	VEGFR; FLT; c-RET; Bcr-Abl; c-Kit	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	AST 487 (NVP-AST 487) 是 RET 激酶抑制剂 (IC50:880 nM)，能够抑制 RET 自磷酸化，及下游效应器激活，也抑制 Flt-3 (IC50:520 nM)。
T8541	Lenvatinib mesylate 仑伐替尼甲酸盐,E7080 (mesylate),乐伐替尼	VEGFR; FGFR; c-RET; PDGFR; c-Kit	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Lenvatinib mesylate (E7080 (mesylate)) 是一种口服具有活力的，多靶点酪氨酸激酶抑制剂，能够抑制血管内皮生长因子受体(VEGFR1-3)，成纤维细胞生长因子受体(FGFR1-4)，干细胞因子受体(KIT)，血小板衍生生长因子受体(PDGFR)，转染期间重排(RET)，具有效抗癌作用。
T2516	Amuvatinib MP470,HPK 56	Apoptosis; FLT; c-Met/HGFR; c-RET; DNA/RNA Synthesis; PDGFR; c-Kit	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors
	Amuvatinib (MP470) 是一种多靶点酪氨酸激酶抑制剂，对突变 c-Kit，PDGFRα，Flt3，c-Met 和 c-Ret 具有活性。它还是一种 DNA 修复抑制剂，靶向蛋白 DNA 修复 RAD51，从而破坏 DNA 损伤修复，具有抗肿瘤活性。
T9251	Fedratinib hydrochloride hydrate TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate	Apoptosis; JAK	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) 是一种选择性的，ATP 竞争性和具有口服活性的JAK2抑制剂，对于JAK2和JAK2V617F 激酶的IC50均为 3 nM。它可诱导癌细胞凋亡，可研究骨髓增生性疾病。
T1792	Regorafenib BAY 73-4506,瑞戈非尼,Fluoro-Sorafenib,瑞格非尼	Raf; VEGFR; c-RET; PDGFR; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
	Regorafenib (BAY 73-4506) 是一种多靶点受体酪氨酸激酶抑制剂，抑制 RET、C-RAF、VEGFR2、c-Kit、VEGFR1 和 PDGFRβ (IC50=1.5/2.5/4.2/7/13/22 nM)，具有口服活性。Regorafenib 具有抗肿瘤和抗血管生成活性。
T6028	PF 477736 PF 00477736,PF-477736,PF-736,PF-00477736,PF477736	c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂，Ki 值为0.49 nM。它也是Chk2抑制剂，Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。

化合物

Cat.No: T9673

Target: c-RET

RET V804M-IN-1

Cat.No: T8467

Synonym: RETV804M kinase inhibitor,LUN09945

Target: c-RET

Cat.No: T69644

Synonym: RET-IN-21

Target: c-RET

Cat.No: T40097

Target: Others

Cat.No: T16735

Target: Others

Cat.No: T8222

Synonym: LOXO-292

Target: c-RET

Cat.No: T73309

Target: Others

Cat.No: T78683

Target: Others

Cat.No: T63358

Target: Others

Cat.No: T79099

Target: Others

Cat.No: T63772

Target: Others

Cat.No: T79163

Target: Others

Cat.No: T79726

Target: Others

Cat.No: T64103

Target: Others

Cat.No: T63468

Target: Others

Cat.No: T63837

Target: Others

Cat.No: T63782

Target: Others

Cat.No: T63249

Target: Others

Cat.No: T63877

Target: Others

Cat.No: T62877

Target: Others

Cat.No: T63230

Target: Others

Cat.No: T73256

Target: Others

Cat.No: T73248

Target: Others

Cat.No: T63583

Target: Others

Cat.No: T81296

Target: Others

Cat.No: T63183

Target: Others

Cat.No: T12598

Target: VEGFR, c-RET

Cat.No: T10624

Target: c-RET

Cat.No: T16923

Target: c-RET

Cat.No: TQ0277

Synonym: 普拉替尼,Blu667

Target: c-RET

Cat.No: T67733

Target: Others

Cat.No: T4301

Target: Raf, c-RET, Src, S6 Kinase

Cat.No: T2282

Target: Others, Phospholipase, c-Met/HGFR, c-RET

Cat.No: T5491

Target: c-RET

Cat.No: T7418

Synonym: NVP-BBT594

Target: c-RET

Cat.No: T3065

Target: Apoptosis, FLT, c-RET, JAK, Autophagy

Cat.No: T22349

Synonym: CS-2660

Target: VEGFR, c-RET, c-Kit

Cat.No: T1995

Synonym: TG-101348,SAR 302503

Target: Apoptosis, FLT, c-RET, JAK

Regorafenib monohydrate

Cat.No: T1792L

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Cat.No: T6920

Target: FGFR, c-RET, JAK, CDK, PDGFR, Src, AMPK

Cat.No: T2032

Synonym: Janex 3

Target: EGFR, VEGFR, c-RET, CDK

Regorafenib Hydrochloride

Cat.No: T8402

Synonym: 瑞戈非尼盐酸盐,BAY73-4506 hydrochloride

Target: Raf, VEGFR, c-RET, PDGFR, Autophagy

Cat.No: T0520

Synonym: 仑伐替尼,E7080

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

Cat.No: TD0081

Synonym: EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],EDANS酸,1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht

Target: Others

Cat.No: T4053

Synonym: NVP-AST 487

Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit

Lenvatinib mesylate

Cat.No: T8541

Synonym: 仑伐替尼甲酸盐,E7080 (mesylate),乐伐替尼

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

Cat.No: T2516

Synonym: MP470,HPK 56

Target: Apoptosis, FLT, c-Met/HGFR, c-RET, DNA/RNA Synthesis, PDGFR, c-Kit

Fedratinib hydrochloride hydrate

Cat.No: T9251

Synonym: TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate

Target: Apoptosis, JAK

Cat.No: T1792

Synonym: BAY 73-4506,瑞戈非尼,Fluoro-Sorafenib,瑞格非尼

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Cat.No: T6028

Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase

Cat. No.	Product Name	Target	Signaling Pathways
TN7090	Coretinphencone	Others	Others
	Coretinphencone 是一种从金鸡菊花蕾中分离出来的天然产物。
TJS2190	Nordihydroguaiaretic acid 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid	Antioxidant; Ferroptosis; Lipoxygenase; Autophagy	Apoptosis; Autophagy; Metabolism; oxidation-reduction
	Nordihydroguaiaretic acid (NDGA) 是从极叉开拉瑞阿提取出的一种天然产物，是脂氧合酶抑制剂，具有抗氧化和清除自由基的特性。
T2924	Phloretin 根皮素,Dihydronaringenin,NSC 407292,RJC 02792	SGLT; transporter; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Phloretin (NSC-407292) 是从苹果树叶中提取的一种查耳酮，具有抗炎、抗氧化和抗癌活性。它是真核尿素转运蛋白抑制剂，可阻断 VacA 介导的尿素和离子转运，有潜力用于类风湿性关节炎和过敏性气道炎症的相关研究。
TN2148	Retusin 5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether	ATPase; Free radical scavengers; Tyrosinase	Membrane transporter/Ion channel; oxidation-reduction; Proteases/Proteasome
	Retusin 是从 Talinum triangulare 的叶子中提取的。 Retusin Retusin 可用于作为芽前和芽后除草剂的研究。
T1059	Retinyl palmitate Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Retinyl palmitate (Vitamin A palmitate) 是酯化的视黄醇，是表皮中维生素 A 的主要形式，在药品和化妆品中有广泛应用。
T1611	Isotretinoin 13-cis-Retinoic acid,异维A酸	Retinoid Receptor; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Isotretinoin (13-cis-Retinoic acid) 是一种天然存在的维甲酸，具有潜在的抗肿瘤活性。它结合并激活核视黄酸受体 (RAR)，活化的 RARs 作为促进细胞分化和凋亡的转录因子。它是一种类维生素A 和维生素A 衍生物，用于治疗严重的痤疮和某些形式的皮肤、头颈癌。
T7408	all-trans-4-Oxoretinoic acid 4-KETO全反式维甲酸,all-trans 4-Keto Retinoic Acid	Endogenous Metabolite	Metabolism
	all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid) 是一种维生素A 的特性代谢物，能够通过作用核维甲酸受体(RARs) 来诱导基因转录。
T5256	All-trans-retinal 视黄醛,All trans-Retinal,Retinaldehyde,Vitamin A aldehyde	Others; Endogenous Metabolite	Metabolism; Others
	All-trans-retinal (Vitamin A aldehyde) 是视网膜中维生素A 代谢物之一。生理条件下，它再生为视觉发色团，11-顺式-视黄醛。
T6212	Combretastatin A4 CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09	Microtubule Associated	Cytoskeletal Signaling
	Combretastatin A4 (CA4) 是一种微管靶向剂，可结合 β-tubulin，Kd 值为 0.4 μM。
TN7082	demethyldaphnoretin-7-O-glucoside	Others	Others
	demethyldaphnoretin-7-O-glucoside 是从 Daphne oleoides Schreber subsp. 中分离出来的天然产物。在土耳其传统医学中，它的地上部分已被用于治疗疟疾、风湿病和伤口愈合。
T2842	Tangeretin NSC53909,Tangeritin,NSC618905,桔皮素	Apoptosis; Gamma-secretase	Apoptosis; Neuroscience; Proteases/Proteasome; Stem Cells
	Tangeretin (NSC-618905) 是一种来自柑橘类水果果皮的类黄酮，是一种Notch-1抑制剂，具有抗炎，保护神经等作用。
T0051	Urethane Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯	Chloride channel; GABA Receptor; Antibacterial; GluR; NMDAR; AChR; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Urethane (Ethylurethane) 是多种食品中发酵形成的副产物，是氨基甲酸的乙酯，具有抑制细菌、海胆卵、原生动物和植物组织生长的作用。
TN1733	Hesperetin 7-O-glucoside	Anti-infection; Antibacterial; HMG-CoA Reductase	Metabolism; Microbiology/Virology
	Hesperetin 7-O-glucoside 是通过 Hesperidin 的酶促转化产生的一种人 HMG-CoA 还原酶抑制剂，具有降压作用，可抑制幽门螺杆菌的生长。
T1330	Acitretin 阿曲汀,Ro 10-1670,Etretin	Apoptosis; Retinoid Receptor; Autophagy	Apoptosis; Autophagy; Metabolism
	Acitretin (Ro 10-1670) 是一种维甲酸，可用于银屑病和阿尔兹海默症的研究。
T1051	Retinoic acid 维生素A酸,Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin	Retinoid Receptor; Endogenous Metabolite; PPAR; Autophagy	Autophagy; DNA Damage/DNA Repair; Metabolism
	Retinoic acid (Tretinoin) 是维生素 A 的代谢产物，是一种视黄酸受体 RAR 的天然激动剂，激动 RARα/β/γ (IC50=14 nM)。Retinoic acid 可以诱导细胞分化、减少细胞增殖和抑制肿瘤发生。
T4S1335	Daphnoretin Dephnoretin,西瑞香素,Thymelol	Influenza Virus; Caspase; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Daphnoretin (Thymelol) 是从了哥王中提取得到的一种天然产物，具有抗癌和抗病毒活性。它通过在 G2/M 期连续阻断细胞并激活 caspase-3 通路导致 HOS 细胞死亡。
TN2244	Sulfuretin 硫黄菊素	NF-κB; Autophagy	Autophagy; NF-κB
	Sulfuretin 是竞争性单酚酶和二酚酶活性抑制剂，IC50=13.64 μM。它通过抑制NF-κB 通路来抑制炎症反应。它可用于过敏性气道炎症的研究。它减少氧化应激、血小板聚集和诱变。
T1183	Retinol all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin	Others	Others
	Retinol (Vitamin A) 属于天然维生素，具有脂溶性。Retinol 在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。
T4955	saponaretin Isovitexin,Apigenin-6-C-glucoside,异牧荆素	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	saponaretin 是许多中药的活性成分，具有多种活性，如抗氧化、抗炎、抗阿尔茨海默病（AD）作用等。
T6272	Fosbretabulin Disodium Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Fosbretabulin Disodium (CA 4P) 是一种微管蛋白去稳定剂，是 Combretastatin A4 前药，可选择性靶向内皮细胞，诱导新生肿瘤新血管消退，减少肿瘤血流量并引起中央肿瘤坏死。
T2565	Hesperetin 橙皮素	Apoptosis; p38 MAPK; 5-HT Receptor; Autophagy; TGF-beta/Smad	Apoptosis; Autophagy; GPCR/G Protein; MAPK; Neuroscience; Stem Cells
	Hesperetin 是一种天然黄烷酮类物质，是人UGT 的广谱抑制剂，可诱导凋亡。
TQ0280	Feretoside	HSP	Cytoskeletal Signaling; Metabolism
	Feretoside 是分离自杜仲树皮的一种酚类化合物。它是 HSP 诱导剂，可作为细胞保护剂。
T0685	Retinyl acetate Vitamin A acetate,Retinyl (Retinol) Acetate,视黄醇乙酸酯(维生素A醋酸酯),Retinol acetate,视黄醇乙酸酯
	Retinyl acetate (Vitamin A acetate) 是一种视黄醇的合成乙酸酯形式衍生物，有抗肿瘤和化学预防活性的潜能。
T8152	6-Demethoxytangeretin	MAPK; ALK	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	6-Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用，通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。
TN3312	9-Angeloylretronecine N-oxide	Others	Others
	9-Angeloylretronecine N-oxide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3312，CAS号为 27773-86-0。
TN1581	Dihydroguaiaretic acid 二氢愈创木酸	COX; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience
	Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
T28021	meso-Dihydroguaiaretic acid
	meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
T19169	9-cis-Retinal	Others	Others
	9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and maturation of rod photoreceptors in r
T81015	Terretonin A
	Terretonin A为一类萜化合物，可从Aspergillus terreus中分离获得。
T83401	2′-O-Methylphloretin	Others	Others
	2′-O-Methylphloretin是一种从Melodorum siamensis叶子中分离出的类黄酮衍生物，具有抑制肿瘤细胞系复制的生物活性。
TN4206	Hesperetin 5-O-glucoside	Others	Others
	Hesperetin 5-O-glucoside has hypocholesterolemic effect.
TN5127	Tereticornate A	Others	Others
	Tereticornate A是一种天然产物，属于桃金娘科桉属，其产品编号为 TN5127，CAS号为 149751-81-5。Tereticornate A可用作对照参考。
T79973	Dehydrodiscretamine chloride	Others	Others
	Dehydrodiscretamine chloride作为AChE和BChE的双重抑制剂，展现了其抑制效力，其中对AChE的IC50为17.8 μM，对BChE的IC50为118.8 μM。此外，该化合物具备抗氧化活性，并可被应用于阿尔茨海默病相关研究。
TN7510	all-trans-13,14-Dihydroretinol	Others	Others
	All-trans-13,14-Dihydroretinol, a metabolite of all-trans-retinoic acid, is synthesized through the enzymatic action of retinol saturase on all-trans-retinoic acid.
TN4278	Isodaphnoretin B	Others	Others
	Isodaphnoretin B is a natural product from Stellera chamaejasme.
TN2146	Retronecine N-oxide 倒千里光碱氮氧化物	Others	Others
	Retronecine N-oxide is a natural product
T81291	Retrofractamide A
	Retrofratamide A为源自Piper chaba果实的酰胺，能够促进3T3-L1细胞的脂肪生成。
T83581	(±)-Reticuline	Others	Others
	(±)-Reticuline（化合物3f），波尔多叶（Peumus boldus Molina）中的天然产物，用于合成S-Reticuline。
T40665	Uvaretin	Others	Others
	Uvaretin demonstrates potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM).
T32198	Retrorsine N-oxide Isatidine	Others	Others
	Isatidine is a pyrrolizidine alkaoid.
TN7552	Luteoreticulin Griseulin	Others	Others
	Luteoreticulin, a nitro-containing bacterial metabolite first isolated from S. luteoreticuli, exhibits mosquitocidal activity against A. aegypti at a concentration of 6.25 mg/L and nematocidal activity against C. elegans.
T12667	(Rac)-Hesperetin	Others	Others
	(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits potent inhibitory effects against human UGT activity, making it a broad-spectrum inhibitor. Furthermore, Hesperetin induces apoptosis through the activation of p38 MAPK.
TN2572	10-O-Caffeoyl-6-epiferetoside	Others	Others
	10-O-Caffeoyl-6-epiferetoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2572，CAS号为 83348-22-5。
TN6497	Hesperetin-7-methyl ether
	Hesperetin-7-methyl ether is a natural prooduct from Citrus maxima.
TN3718	Creticoside C	Others	Others
	Creticoside C 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3718，CAS号为 53452-34-9。
TN3221	7-Angeloylretronecine	Antifection	Microbiology/Virology
	7-Angeloylretronecine may have antibacterial effects.
TN4640	Neophellamuretin	Others	Others
	Neophellamuretin is a natural product from Akschindlium godefroyanum (Kuntze) H. Ohashi.
TN4930	Rutaretin	Others	Others
	Rutaretin是一种天然产物，属于芸香科芸香属，其产品编号为 TN4930，CAS号为 13895-92-6。Rutaretin可用作对照参考。
TN2145	Retronecine	Others	Others
	Retronecine acts as the better competitor for the competitive inhibition of antibodies to Retronecine.
T83917	6-O-Methylreticulol 8-hydroxy-6,7-dimethoxy-3-methyl Isocoumarin	Others	Others
	6-O-Methylreticulol是一种异香豆素(isocoumarin)及真菌代谢产物，已在S. mobaraensis中被发现。
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天然产物

Coretinphencone

Cat.No: TN7090

Target: Others

Nordihydroguaiaretic acid

Cat.No: TJS2190

Synonym: 去甲二氢愈创木酸,NDGA,Dihydronorguaiaretic Acid

Target: Antioxidant, Ferroptosis, Lipoxygenase, Autophagy

Cat.No: T2924

Synonym: 根皮素,Dihydronaringenin,NSC 407292,RJC 02792

Target: SGLT, transporter, Endogenous Metabolite

Cat.No: TN2148

Synonym: 5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether

Target: ATPase, Free radical scavengers, Tyrosinase

Retinyl palmitate

Cat.No: T1059

Synonym: Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate,维生素A棕榈酸酯

Target: Others, Endogenous Metabolite

Cat.No: T1611

Synonym: 13-cis-Retinoic acid,异维A酸

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

all-trans-4-Oxoretinoic acid

Cat.No: T7408

Synonym: 4-KETO全反式维甲酸,all-trans 4-Keto Retinoic Acid

Target: Endogenous Metabolite

All-trans-retinal

Cat.No: T5256

Synonym: 视黄醛,All trans-Retinal,Retinaldehyde,Vitamin A aldehyde

Target: Others, Endogenous Metabolite

Combretastatin A4

Cat.No: T6212

Synonym: CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09

Target: Microtubule Associated

demethyldaphnoretin-7-O-glucoside

Cat.No: TN7082

Target: Others

Cat.No: T2842

Synonym: NSC53909,Tangeritin,NSC618905,桔皮素

Target: Apoptosis, Gamma-secretase

Cat.No: T0051

Synonym: Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯

Target: Chloride channel, GABA Receptor, Antibacterial, GluR, NMDAR, AChR, Parasite

Hesperetin 7-O-glucoside

Cat.No: TN1733

Target: Anti-infection, Antibacterial, HMG-CoA Reductase

Cat.No: T1330

Synonym: 阿曲汀,Ro 10-1670,Etretin

Target: Apoptosis, Retinoid Receptor, Autophagy

Retinoic acid

Cat.No: T1051

Synonym: 维生素A酸,Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin

Target: Retinoid Receptor, Endogenous Metabolite, PPAR, Autophagy

Cat.No: T4S1335

Synonym: Dephnoretin,西瑞香素,Thymelol

Target: Influenza Virus, Caspase, PKC

Cat.No: TN2244

Synonym: 硫黄菊素

Target: NF-κB, Autophagy

Cat.No: T1183

Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Target: Others

Cat.No: T4955

Synonym: Isovitexin,Apigenin-6-C-glucoside,异牧荆素

Target: Apoptosis, Antioxidant

Fosbretabulin Disodium

Cat.No: T6272

Synonym: Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium

Target: Apoptosis, Microtubule Associated

Cat.No: T2565

Synonym: 橙皮素

Target: Apoptosis, p38 MAPK, 5-HT Receptor, Autophagy, TGF-beta/Smad

Cat.No: TQ0280

Target: HSP

Retinyl acetate

Cat.No: T0685

Synonym: Vitamin A acetate,Retinyl (Retinol) Acetate,视黄醇乙酸酯(维生素A醋酸酯),Retinol acetate,视黄醇乙酸酯

6-Demethoxytangeretin

Cat.No: T8152

Target: MAPK, ALK

9-Angeloylretronecine N-oxide

Cat.No: TN3312

Target: Others

Dihydroguaiaretic acid

Cat.No: TN1581

Synonym: 二氢愈创木酸

Target: COX, DNA/RNA Synthesis

meso-Dihydroguaiaretic acid

Cat.No: T28021

9-cis-Retinal

Cat.No: T19169

Target: Others

Cat.No: T81015

2′-O-Methylphloretin

Cat.No: T83401

Target: Others

Hesperetin 5-O-glucoside

Cat.No: TN4206

Target: Others

Tereticornate A

Cat.No: TN5127

Target: Others

Dehydrodiscretamine chloride

Cat.No: T79973

Target: Others

all-trans-13,14-Dihydroretinol

Cat.No: TN7510

Target: Others

Isodaphnoretin B

Cat.No: TN4278

Target: Others

Retronecine N-oxide

Cat.No: TN2146

Synonym: 倒千里光碱氮氧化物

Target: Others

Retrofractamide A

Cat.No: T81291

(±)-Reticuline

Cat.No: T83581

Target: Others

Cat.No: T40665

Target: Others

Retrorsine N-oxide

Cat.No: T32198

Synonym: Isatidine

Target: Others

Cat.No: TN7552

Synonym: Griseulin

Target: Others

(Rac)-Hesperetin

Cat.No: T12667

Target: Others

10-O-Caffeoyl-6-epiferetoside

Cat.No: TN2572

Target: Others

Hesperetin-7-methyl ether

Cat.No: TN6497

Cat.No: TN3718

Target: Others

7-Angeloylretronecine

Cat.No: TN3221

Target: Antifection

Neophellamuretin

Cat.No: TN4640

Target: Others

Cat.No: TN4930

Target: Others

Cat.No: TN2145

Target: Others

6-O-Methylreticulol

Cat.No: T83917

Synonym: 8-hydroxy-6,7-dimethoxy-3-methyl Isocoumarin

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02270	RET Protein, Human, Recombinant (His) MTC1,PTC,HSCR1,RET51,ret proto-oncogene,CD...	Human	HEK293 Cells
	RET Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.1 kDa and the accession number is P07949-1.
TMPY-04418	RET Protein, Human, Recombinant (aa 658-1114, His & GST) HSCR1,RET51,CDHR16,RET-ELE1,ret p...	Human	Baculovirus Insect Cells
	RET Protein, Human, Recombinant (aa 658-1114, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.7 kDa and the accession number is P07949-1.
TMPH-00131	Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) Ribonuclease mitogillin,Restrictocin,ret	Aspergillus restrictus	E. coli
	This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.9 kDa and the accession number is P67876.
TMPJ-00290	GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) TRNR2,GDNFR-beta,TGF-β-related neurotrophic factor receptor ...	Human	HEK293 Cells
	GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kina...
TMPY-01756	Transthyretin Protein, Human, Recombinant (His) PALB,HEL111,CTS,transthyretin,CTS1,HsT2651,TBPA	Human	HEK293 Cells
	Transthyretin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is E9KL36.
TMPY-04675	SG3/Secretogranin 3, Mouse, Recombinant (His) AI385542,SgIII,1B1075,Chgd,secretogranin III	Mouse	HEK293 Cells
	SG3/Secretogranin 3, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is P47867-1.
TMPY-02182	CD4 Protein, Ferret, Recombinant (His) CD4 molecule	Ferret	HEK293 Cells
	CD4 Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is I6LI22.
TMPK-01090	Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His) Prealbumin,TBPA,CTS,HEL111,Transthyretin,TTR,ATTR,C...	Cynomolgus	HEK293 Cells
	Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.
TMPY-00086	Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His) reticulocalbin 3, EF-hand calcium binding domain	Rat	HEK293 Cells
	Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is I6L9G5.
TMPY-03968	Secretogranin II Protein, Human, Recombinant (His) EM66,SgII,SN,CHGC,secretogranin II	Human	HEK293 Cells
	Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell devel...
TMPY-03994	SG3/Secretogranin 3 Protein, Human, Recombinant (His) secretogranin III,SGIII,UNQ2502/PRO5990	Human	HEK293 Cells
	SG3/Secretogranin 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is AAH14539.1.
TMPH-02559	Calreticulin Protein, Mouse, Recombinant (GST) ERp60,Calreticulin,Endoplasmic reticulum r...	Mouse	E. coli
	Calreticulin Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 73.3 kDa and the accession number is P14211.
TMPH-02069	Secretogranin-2 Protein, Human, Recombinant (GST & His) Secretogranin-2,Chromogranin-C,Secretogran...	Human	E. coli
	Secretogranin-2 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPH-02027	RETNLB Protein, Human, Recombinant (His) Colon carcinoma-related gene protein,Colon and small intesti...	Human	E. coli
	Probable hormone. RETNLB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is Q9BQ08.
TMPY-03664	IFN gamma Protein, Ferret, Recombinant (His) interferon, gamma,interferon, γ,IFN γ,干扰素	Ferret	HEK293 Cells
	IFN gamma Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A4PIZ9.
TMPY-06948	Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated Harvey rat sarcoma viral oncogene homolog	H1N1	Baculovirus Insect Cells
	Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 59.79 kDa and the accession number is AAP34324.1.
TMPY-04672	Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His) D530026G20Rik,6030455P07Rik,D7Ertd671e,RLP49,reticu...	Mouse	HEK293 Cells
	Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.9 kDa and the accession number is Q8BH97.
TMPY-03259	Calreticulin Protein, Human, Recombinant (His) HEL-S-99n,cC1qR,SSA,CRT,RO,calreticulin	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is P27797.
TMPY-03181	Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His) RLP49,reticulocalbin 3, EF-hand calcium binding dom...	Human	HEK293 Cells
	Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q96D15.
TMPY-03258	Calreticulin Protein, Human, Recombinant (hFc) RO,cC1qR,HEL-S-99n,CRT,calreticulin,SSA	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73 kDa and the accession number is P27797.
TMPK-00583	TNF alpha Protein, Ferret, Recombinant (His) TNF-α,DIF,TNFα,TNF-alpha,TNF α,Cachectin,APC1 protein,TNF,TN...	Ferret	E. coli
	TNF alpha Protein, Ferret, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.88 kDa and the accession number is A3FBF1.
TMPH-02242	Transthyretin Protein, Human, Recombinant (hFc & Myc) TTR,ATTR,Transthyretin,Prealbumin,TBPA	Human	HEK293 Cells
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-02034	Retinoschisin Protein, Human, Recombinant (His) Retinoschisin,X-linked juvenile retinoschi...	Human	E. coli
	Retinoschisin Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-02226	TNF alpha Protein, Ferret, Recombinant tumor necrosis factor,肿瘤坏死因子,TNF-α	Ferret	E. coli
	TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
TMPY-06327	Calreticulin Protein, Human, Recombinant HEL-S-99n,calreticulin,cC1qR,CRT,RO,SSA	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.99 kDa and the accession number is P27797.
TMPK-00673	SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His) SCG3,Secretogranin-3,UNQ2502/PRO5990,SGIII,Secr...	Cynomolgus	HEK293 Cells
	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Cynomolgus...
TMPH-00034	ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His) Protein p12,Pret-110,Inner membrane protein p12	ASFV	E. coli
	Virus attachment protein. ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 12.7 kDa and the accession number is P0C9Y3.
TMPH-03105	Calreticulin Protein, Pig, Recombinant (His) Endoplasmic reticulum resident protein 60,CRP55,CRT...	Sus scrofa (Pig)	P. pastoris (Yeast)
	Calreticulin Protein, Pig, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 48.6 kDa and the accession number is P28491.
TMPH-02558	Calreticulin Protein, Mouse, Recombinant (His) ERp60,CRP55,CRT,CALR,Calregulin,Calreticulin,Endopl...	Mouse	P. pastoris (Yeast)
	Calreticulin Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 48.3 kDa and the accession number is P14211.
TMPH-00319	Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) yscF	Burkholderia thailandensis	P. pastoris (Yeast)
	Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 11.9 kDa and the accession number is Q2T727.
TMPH-00813	Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His) Protein ORF2,Pro-secreted protein ORF2	HEV-1	Baculovirus Insect Cells
	Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes. Hepatitis E virus gen...
TMPH-02068	Secretogranin-1 Protein, Human, Recombinant (GST & His) Secretogranin I,Chromogranin-B,Secretogran...	Human	E. coli
	Secretogranin-1 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPH-02946	Transthyretin Protein, Mouse, Recombinant (His & SUMO) Transthyretin,Prealbumin,Ttr	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.6 kDa and the accession number is P07309.
TMPH-02926	TRET Protein, Mouse, Recombinant (His & SUMO) Telomerase catalytic subunit,Telomerase reverse transcriptas...	Mouse	E. coli
	TRET Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is O70372.
TMPY-02165	CD8 alpha Protein, Ferret, Recombinant (His) CD8a molecule,CD8 α	Ferret	HEK293 Cells
	CD8 alpha Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is I6LI23.
TMPY-04919	Transthyretin Protein, Mouse, Recombinant (His) AI787086,prealbumin,D17860,AA408768,transthyretin	Mouse	HEK293 Cells
	Transthyretin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is P07309.
TMPY-02218	CD20 Protein, Ferret, Recombinant (His) membrane-spanning 4-domains, subfamily A, member 1	Ferret	HEK293 Cells
	CD20 Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa.
TMPK-01122	SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) SCG3,Secretogranin III,UNQ2502/PRO5990,Secret	Human	HEK293 Cells
	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Rec...
TMPH-00436	Calreticulin Protein, Cricetulus griseus, Recombinant (His) ERp60,Calreticulin,Calregulin,CRT,CRP55,HACBP,CALR,...	Chinese hamster	P. pastoris (Yeast)
	Calreticulin Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 48.1 kDa and the accession number is Q8K3H7.
TMPH-03368	SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) Scg3,1B1075,Secretogranin-3,Secretogranin ...	Rat	E. coli
	Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway. SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.2 kDa and the accessio...
TMPH-02030	Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) Reticulocalbin-1,RCN1	Human	P. pastoris (Yeast)
	Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02947	Transthyretin Protein, Mouse, Recombinant Prealbumin,Transthyretin,Ttr	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.5 kDa and the accession number is P07309.
TMPH-00757	Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His) BBE1,Tetrahydroprotoberberine synthase,Berberine bridge-form...	Eschscholzia californica	E. coli
	Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
TMPH-03247	Artemin Protein, Rat, Recombinant (His & Myc) Artemin,Artn	Rat	E. coli
	Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Artemin Protein, Rat, Recombinant (His & Myc) is expressed in E. coli ...
TMPH-02842	CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO) CD133,Prom1,Prominin-like protein 1,Prom,Proml1,Antigen AC13...	Mouse	E. coli
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
TMPK-00109	Artemin Protein, Human, Recombinant (hFc) ARTNE,ARTN,Neublastin,Enovin,Artemin,NBN,EVN	Human	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons.
TMPY-04207	Motilin Protein, Human, Recombinant (His) MLN,Motilin	Human	HEK293 Cells
	MLN (Motilin) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. The encoded protein belongs to the motilin family. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). MLN plays an important role in the regulation of Interdigestive...
TMPJ-00100	Artemin Protein, Human, Recombinant ARTN,Artemin,EVN,Enovin,Neublastin	Human	E. coli
	Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a variable length pre-, or signal sequence, plus a 68 amino acid (aa) proregion and a 113 aa mature segment. Following synthesis and proteolytic processing, mature ARTN is secreted as a presumably glycosylated, 28 kDa disulfide-linked homodimer that contains three intrachain disulfide bonds and the typical TGF-β signature cysteine-knot motif. I...
TMPH-00001	CD133/PROM1 Protein-VLP, Human, Recombinant (His) Proml1,Prom1,CD133,Prominin-like protein 1,Antigen AC133 hom...	Human	HEK293 Cells
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. CD133/PROM1 Protein...
TMPJ-01414	GDF-15 Protein, Mouse, Recombinant (His & Flag) Growth Differentiation Factor 15, Macrophage inhibitory cyto...	Mouse	HEK293 Cells
	Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito...
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重组蛋白

RET Protein, Human, Recombinant (His)

Cat.No: TMPY-02270

Species: Human

Expression System: HEK293 Cells

RET Protein, Human, Recombinant (aa 658-1114, His & GST)

Cat.No: TMPY-04418

Species: Human

Expression System: Baculovirus Insect Cells

Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc)

Cat.No: TMPH-00131

Species: Aspergillus restrictus

Expression System: E. coli

GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00290

Species: Human

Expression System: HEK293 Cells

Transthyretin Protein, Human, Recombinant (His)

Cat.No: TMPY-01756

Species: Human

Expression System: HEK293 Cells

SG3/Secretogranin 3, Mouse, Recombinant (His)

Cat.No: TMPY-04675

Species: Mouse

Expression System: HEK293 Cells

CD4 Protein, Ferret, Recombinant (His)

Cat.No: TMPY-02182

Species: Ferret

Expression System: HEK293 Cells

Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01090

Species: Cynomolgus

Expression System: HEK293 Cells

Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His)

Cat.No: TMPY-00086

Species: Rat

Expression System: HEK293 Cells

Secretogranin II Protein, Human, Recombinant (His)

Cat.No: TMPY-03968

Species: Human

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03994

Species: Human

Expression System: HEK293 Cells

Calreticulin Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02559

Species: Mouse

Expression System: E. coli

Secretogranin-2 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-02069

Species: Human

Expression System: E. coli

RETNLB Protein, Human, Recombinant (His)

Cat.No: TMPH-02027

Species: Human

Expression System: E. coli

IFN gamma Protein, Ferret, Recombinant (His)

Cat.No: TMPY-03664

Species: Ferret

Expression System: HEK293 Cells

Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated

Cat.No: TMPY-06948

Species: H1N1

Expression System: Baculovirus Insect Cells

Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04672

Species: Mouse

Expression System: HEK293 Cells

Calreticulin Protein, Human, Recombinant (His)

Cat.No: TMPY-03259

Species: Human

Expression System: HEK293 Cells

Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03181

Species: Human

Expression System: HEK293 Cells

Calreticulin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03258

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Ferret, Recombinant (His)

Cat.No: TMPK-00583

Species: Ferret

Expression System: E. coli

Transthyretin Protein, Human, Recombinant (hFc & Myc)

Cat.No: TMPH-02242

Species: Human

Expression System: HEK293 Cells

Retinoschisin Protein, Human, Recombinant (His)

Cat.No: TMPH-02034

Species: Human

Expression System: E. coli

TNF alpha Protein, Ferret, Recombinant

Cat.No: TMPY-02226

Species: Ferret

Expression System: E. coli

Calreticulin Protein, Human, Recombinant

Cat.No: TMPY-06327

Species: Human

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00673

Species: Cynomolgus

Expression System: HEK293 Cells

ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His)

Cat.No: TMPH-00034

Species: ASFV

Expression System: E. coli

Calreticulin Protein, Pig, Recombinant (His)

Cat.No: TMPH-03105

Species: Sus scrofa (Pig)

Expression System: P. pastoris (Yeast)

Calreticulin Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02558

Species: Mouse

Expression System: P. pastoris (Yeast)

Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His)

Cat.No: TMPH-00319

Species: Burkholderia thailandensis

Expression System: P. pastoris (Yeast)

Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His)

Cat.No: TMPH-00813

Species: HEV-1

Expression System: Baculovirus Insect Cells

Secretogranin-1 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-02068

Species: Human

Expression System: E. coli

Transthyretin Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02946

Species: Mouse

Expression System: E. coli

TRET Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02926

Species: Mouse

Expression System: E. coli

CD8 alpha Protein, Ferret, Recombinant (His)

Cat.No: TMPY-02165

Species: Ferret

Expression System: HEK293 Cells

Transthyretin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04919

Species: Mouse

Expression System: HEK293 Cells

CD20 Protein, Ferret, Recombinant (His)

Cat.No: TMPY-02218

Species: Ferret

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)

Cat.No: TMPK-01122

Species: Human

Expression System: HEK293 Cells

Calreticulin Protein, Cricetulus griseus, Recombinant (His)

Cat.No: TMPH-00436

Species: Chinese hamster

Expression System: P. pastoris (Yeast)

SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03368

Species: Rat

Expression System: E. coli

Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02030

Species: Human

Expression System: P. pastoris (Yeast)

Transthyretin Protein, Mouse, Recombinant

Cat.No: TMPH-02947

Species: Mouse

Expression System: E. coli

Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His)

Cat.No: TMPH-00757

Species: Eschscholzia californica

Expression System: E. coli

Artemin Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03247

Species: Rat

Expression System: E. coli

CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02842

Species: Mouse

Expression System: E. coli

Artemin Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00109

Species: Human

Expression System: HEK293 Cells

Motilin Protein, Human, Recombinant (His)

Cat.No: TMPY-04207

Species: Human

Expression System: HEK293 Cells

Artemin Protein, Human, Recombinant

Cat.No: TMPJ-00100

Species: Human

Expression System: E. coli

CD133/PROM1 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-00001

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein, Mouse, Recombinant (His & Flag)

Cat.No: TMPJ-01414

Species: Mouse

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0039	Norethindrone Acetate-2,2,4,6,6,10-d6
	Norethindrone Acetate-2,2,4,6,6,10-d6 是 Norethindrone Acetate 的氘代化合物。Norethindrone Acetate 的 CAS 号为 51-98-9。Norethindrone acetate 是一种雌性激素，对青少年月经和肝腺瘤有抑制作用，常与孕激素联合使用，可用于研究子宫内膜异位症。
TMIH-0470	R-(-)-Tretoquinol Hydrochloride-d9
	R-(-)-Tretoquinol Hydrochloride-d9 是 R-(-)-Tretoquinol Hydrochloride 的氘代化合物。
TMIH-0510	S-(-)-Tretoquinol Hydrochloride-d9
	S-(-)-Tretoquinol Hydrochloride-d9 是 S-(-)-Tretoquinol Hydrochloride 的氘代化合物。
TMID-0131	Norethindrone-2,2,4,6,6,10-d6
	Norethindrone-2,2,4,6,6,10-d6 是 Norethindrone 的氘代化合物。Norethindrone 的 CAS 号为 68-22-4。Norethindrone 是孕激素，能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。
TMIJ-0382	Norethindrone (Ethynyl-13C2)
	Norethindrone (Ethynyl-13C2) 是 Norethindrone 的 13C 的标记化合物。Norethindrone 的 CAS 号为 68-22-4。Norethindrone 是孕激素，能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。
T19088	13-cis Acitretin D3 Isoacitretin D3,13-cis Acitretin D3	Others	Others
	13-cis Acitretin D3 (Isoacitretin D3) is a deuterium-labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin is a second-generation, systemic retinoid.
T67921	Retinoic acid-d5 all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5	Retinoid Receptor	Metabolism
	Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂，对 RARα/β/γ 的 IC50 为 14 nM，与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物，在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。
TMIJ-0074	Retigabine-d4
	Retigabine-d4 是 Retigabine 的氘代化合物。Retigabine 的 CAS 号为 150812-12-7。Retigabine dihydrochloride 是一种抗惊厥药，用作有治疗经验的成年患者部分性癫痫的辅助治疗。作用机制涉及神经元 K(V)7.2-7.5（以前的 KCNQ2-5）电压激活 K(+) 通道的开放。
TMIJ-0108	rac-Hesperetin-13C-d3 rac-Diosmin EP Impurity G-13C-d3
	rac-Hesperetin-13C-d3 是 rac-Hesperetin 的 13C 和氘代化合物。rac-Hesperetin 的 CAS 号为 69097-99-0。
TMIJ-0360	Urethane-d5
	Urethane-d5 是 Urethane 的氘代化合物。Urethane 的 CAS 号为 51-79-6。Urethane 是多种食品中发酵形成的副产物，是氨基甲酸的乙酯，具有抑制细菌、海胆卵、原生动物和植物组织生长的作用。
TMIJ-0443	3-Keto Fenretinide-d4
	3-Keto Fenretinide-d4 是 3-Keto Fenretinide 的氘代化合物。3-Keto Fenretinide 的 CAS 号为 865536-65-8。4-Oxofenretinide 是一种最近发现的 fenretinide 代谢物，可诱导显着的 G2-M 细胞周期停滞和细胞凋亡。
TMIJ-0125	Regorafenib-13C-d3 N-Oxide
	Regorafenib-13C-d3 N-Oxide 是 Regorafenib N-Oxide 的 13C 和氘代化合物。Regorafenib N-Oxide 的 CAS 号为 835621-11-9。Regorafénib N-oxyde M2 是 Regorafenib 的活性代谢物。Regorafenib 是多靶点抑制剂，包括VEGFR1/2/3，PDGFRβ，Kit，RET 和 Raf-1 ， IC50分别是 13/4.2/46，22，7，1.5 和 2.5 nM。
TMIJ-0124	Regorafenib-13C-d3
	Regorafenib-13C-d3 是 Regorafenib 的 13C 和氘代化合物。Regorafenib 的 CAS 号为 755037-03-7。Regorafenib 是一种多靶点受体酪氨酸激酶抑制剂，对 RET、C-RAF、VEGFR2、c-Kit、VEGFR1和PDGFRβ 的 IC50为1.5、2.5、4.2、7、13和22 nM。
TMIJ-0154	Lenvatinib-d4
	Lenvatinib-d4 是 Lenvatinib 的氘代化合物。Lenvatinib 的 CAS 号为 417716-92-8。Lenvatinib 是一种口服具有活性的，多靶点酪氨酸激酶抑制剂，能够抑制血管内皮生长因子受体(VEGFR1-3)，成纤维细胞生长因子受体(FGFR1-4)，干细胞因子受体(KIT)，血小板衍生生长因子受体(PDGFR)，转染期间重排(RET)，具有效抗癌的作用。

同位素标记化合物

Norethindrone Acetate-2,2,4,6,6,10-d6

Cat.No: TMIJ-0039

R-(-)-Tretoquinol Hydrochloride-d9

Cat.No: TMIH-0470

S-(-)-Tretoquinol Hydrochloride-d9

Cat.No: TMIH-0510

Norethindrone-2,2,4,6,6,10-d6

Cat.No: TMID-0131

Norethindrone (Ethynyl-13C2)

Cat.No: TMIJ-0382

13-cis Acitretin D3

Cat.No: T19088

Synonym: Isoacitretin D3,13-cis Acitretin D3

Target: Others

Retinoic acid-d5

Cat.No: T67921

Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5

Target: Retinoid Receptor

Retigabine-d4

Cat.No: TMIJ-0074

rac-Hesperetin-13C-d3

Cat.No: TMIJ-0108

Synonym: rac-Diosmin EP Impurity G-13C-d3

Cat.No: TMIJ-0360

3-Keto Fenretinide-d4

Cat.No: TMIJ-0443

Regorafenib-13C-d3 N-Oxide

Cat.No: TMIJ-0125

Regorafenib-13C-d3

Cat.No: TMIJ-0124

Cat.No: TMIJ-0154

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