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Search Results for " regulator "
Targets Recommended: IL Receptor

214

抑制剂 & 化合物

41

天然产物

3

化合物库

294

重组蛋白

8

同位素标记化合物

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Cat. No. Product Name
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;
L4300 Wnt/Hedgehog/Notch 通路化合物库

237 compounds
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。

化合物库

HIF-1化合物库
Cat.No: L8500
Compounds: 1336
PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
Wnt/Hedgehog/Notch 通路化合物库
Cat.No: L4300
Compounds: 237
Cat. No. Product Name Target Signaling Pathways
T12218 NFAT Transcription Factor Regulator-1

IL Receptor Immunology/Inflammation
NFAT Transcription Factor Regulator-1 是 IL-2 合成 的抑制剂,IC50 值为182 nM。
T60000 STING (WT/R232) activity regulator 126

STING Immunology/Inflammation
STING (WT/R232) activity regulator 126 是一种具有抗菌和抗病毒作用的 STING 调节剂。
T77804 KRAS G12D mutation regulator 4

Others Others
KRAS G12D mutation regulator 4 可用于 Ras 相关研究。
T82450 ER proteostasis regulator-1

Others Others
ER proteostasis regulator-1 (化合物481) 是高效的内质网蛋白稳态调节剂,其在阿尔茨海默病与糖尿病研究领域显示出潜在应用价值。
T5637 Triflumuron

Others Others
Triflumuron 是一种杀虫剂,属于所谓的昆虫生长调节剂。它抑制昆虫幼虫合成甲壳素,导致死亡。
T1634 Glibenclamide

格列本脲,Glyburide

Potassium Channel; Mitochondrial Metabolism; CFTR; P-gp; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
Glibenclamide (Glyburide) 是一种具有口服活性的 ATP 敏感的 K+通道抑制剂,可研究糖尿病和肥胖。它抑制 P-糖蛋白,可直接结合并阻断 KATP 的 SUR1亚基并抑制囊性纤维化跨膜传导调节蛋白。它通过诱导膜离子通透性干扰线粒体生物能,可诱导自噬。
T14898 CCG-63808

GTPase GPCR/G Protein
CCG-63808 是一种有效的、可逆的G 蛋白信号调节子抑制剂。
T3135 KM11060

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
KM11060 是 F508del-CFTR 运输缺陷的新型校正剂,可纠正 F508del-CFTR 运输,增加质膜上功能性 CFTR 的数量。它可用于 F508del-CFTR 加工缺陷的研究和囊性纤维化治疗剂的开发。
T1805 Ataluren

PTC124

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Ataluren (PTC124) 是一种可口服的 CFTR-G542X 无义等位基因抑制剂。
T4384 Halofenozide

Others Others
Halofenozide 是一种新的昆虫生长调节剂 (IGR),具有苯甲酰肼结构,也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用,
T16681 Nesolicaftor

PTI-428

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Nesolicaftor (PTI-428) 特异性增强囊性纤维化跨膜电导调节蛋白合成。
T2451 GlyH-101

GlyH 101

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
GlyH-101 是一种可渗透入细胞的 CFTR 阻断剂,Ki 为1.4 uM。
T14935 Elexacaftor

VX-445

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Elexacaftor (VX-445) 是一种囊性纤维化跨膜电导调节因子 (CFTR) 校正剂。它促进CFTR 的加工和转运,增加细胞表面CFTR 的数量。
T5312 CFTR corrector 2

FDL169

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
CFTR corrector 2 (FDL169) 是一种新型有效的囊性纤维化跨膜电导调节因子(CFTR)调节剂,用于治疗携带 F508del 突变的囊性纤维化患者。
T9499 Icenticaftor

QBW251

CFTR Membrane transporter/Ion channel
Icenticaftor (QBW251) 是一种具有口服活性CFTR 通道增强剂,可用于慢性阻塞性肺疾病 (COPD) 和囊性纤维化研究,对F508del 和G551D CFTR 的EC50分别为 79 和 497 nM。
T11438 GNE-1858

Others; MAPK MAPK; Others
GNE-1858 是高效的 ATP 竞争性造血祖细胞激酶-1抑制剂,能够抑制野生型(IC50:1.9 nM)、活性模拟突变株 HPK1-TSEE (IC50:1.9 nM)、 HPK1-SA (IC50:4.5 nM)的活性。
T14897 CCG-63802

GTPase GPCR/G Protein
CCG-63802 是选择性的、可逆变构的G 蛋白信号调节子RGS4抑制剂。CCG-63802与RGS4特异性结合从而阻断 RGS4-Gαo 相互作用,IC50为 1.9 μM。
T2486 IOWH-032

IOWH032,IOWH 032

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
IOWH-032 (IOWH032) 是一种合成 CFTR 抑制剂,可用于研究治疗霍乱、腹泻和分泌性腹泻,在T84和CHO-CFTR 细胞实验中IC50为1.01 uM。
T2595 Lumacaftor

鲁玛卡托,VX-809,VRT 826809

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Lumacaftor (VRT 826809) 是一种 CFTR 调节剂,可纠正 CFTR 蛋白的折叠和运输。它增强了 FRT 细胞中 F508del-CFTR 蛋白的成熟,EC50为100 nM。
T7083 GLPG1837

ABBV-974

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
GLPG1837 (ABBV-974) 是一种有效的 CFTR 增强剂,对其 F508del 和 G551D 的 EC50 分别为 3 nM 和 339 nM。
T2588 Ivacaftor

Ivacaftor (VX-770),VX-770,依伐卡托

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Ivacaftor (VX-770) 是一种 CFTR 增强剂,靶向G551D-CFTR 和F508del-CFTR 的EC50分别为100 和 25 nM。
T1874 PPQ-102

PPQ102,CFTR Inhibitor,PPQ 102

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
PPQ-102 (CFTR Inhibitor) 是一种CFTR 抑制剂,可以完全抑制CFTR 氯化物电流,IC50为90 nM。
T10591 BPO-27 racemate

BPO-27 (racemate)

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
BPO-27 racemate (BPO-27(racemate)) 是一种CFTR 抑制剂,IC50为8 nM。
T3495 Tasimelteon

他司美琼,VEC-162,BMS-214778

Melatonin Receptor; MT Receptor GPCR/G Protein; Neuroscience
Tasimelteon (BMS-214778) 是一种褪黑激素受体激动剂,用于治疗盲人的非 24 小时睡眠-觉醒障碍。
T2355 CFTR(inh)-172

CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
CFTR(inh)-172 (CFTR Inhibitor-172) 是一种不依赖电压的选择性 CFTR 抑制剂,在2分钟内可逆地抑制CFTR 短路电流的Ki 值为300 nM。
T6434 CCG-50014

CCG 50014,4-[(4-氟苯基)甲基]-2-(4-甲基苯基)-1,2,4-噻二唑烷-3,5-二酮

GTPase GPCR/G Protein
CCG-50014 是一种有效的选择性 RGS4 抑制剂,IC50 为 30 nM。它在小鼠福尔马林试验中减少伤害性反应并增强阿片类药物介导减缓疼痛的作用。它与 RGS 共价结合,在位于变构调节位点的两个半胱氨酸残基上形成加合物。
T2263 Tezacaftor

VX661,1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基乙基)-1H-吲哚-5-基]-环丙烷甲酰胺

CFTR; Autophagy Autophagy; Membrane transporter/Ion channel
Tezacaftor (VX661) 是一种小分子,可用作囊性纤维化跨膜电导调节器基因功能的校正剂。
TP2340 Hemoregulatory peptide 5b

hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide

Hemoregulatory peptide 5b is a synthetic analog of granulocyte chalone which initially identified in extracts of rodent bone marrow and human leukocytes. Monomer inhibits both formations of GM-CFC colonies and cytotoxic drug-induced recruitment of murine
T20341 DNDS

CFTR Membrane transporter/Ion channel
DNDS 是电压依赖性囊性纤维化跨膜电导调节剂 (CFTR) 的通道阻滞剂。
T10545 BIO-32546

PDE Metabolism
BIO-32546 (S-isomer) 是一种高效的 autotaxin (ATX) 的调节剂,IC50 值为 1 nM。
T5914 Folcisteine

3-Acetylthiazolidine-4-carboxylic acid,半叶素

Others Others
Folcisteine (3-Acetylthiazolidine-4-carboxylic acid) 是植物生长调节剂。
T1832 Walrycin B

Antibacterial; Antibiotic Microbiology/Virology
Walrycin B 是一种能特异地靶向WalR 应答调节子的新型抗菌素。
T77612 WAY-620472

PPAR DNA Damage/DNA Repair; Metabolism
WAY-620472是一种PPAR 调节剂,可用于改变真核生物的寿命。
T20738 Chlormequat chloride

NSC 34858,NSC34858,EI 38,555,NSC-34858,EI-38,555,矮壮素,EI38,555

Others Others
Chlormequat chloride (EI 38,555) 是一种植物生长调节剂,由于它可以促进作物更坚固的生长,因此在农业中得到了广泛的应用。
T5560 Dicyclanil

Others Others
Dicyclanil 是一种化学结构与环丙嗪相似的昆虫生长调节剂。
T7864 Chlorpropham

Others Others
Chlorpropham 作为植物生长调节剂和除草剂。
T22736 DMeOB

3,3'-Dimethoxybenzaldazine

GluR Neuroscience
DMeOB (3,3'-Dimethoxybenzaldazine) 是具有mGluR5 激动剂活性的负调节剂,可用于研究神经系统疾病。
T13809 P62-mediated mitophagy inducer

PMI

Mitophagy Autophagy
P62-mediated mitophagy inducer (PMI) 是一种线粒体自噬调节剂,能激活线粒体自噬,可在缺乏完整功能的 PINK1/Parkin 通路的细胞中保留活性。
T17216 Valspodar

PSC 833

P-gp Membrane transporter/Ion channel; Neuroscience
Valspodar (PSC 833) 是一种特异性的 P-糖蛋白抑制剂和MDR调节剂,常被用作化学增敏剂,可用于研究晚期上皮卵巢癌。
T15711 Larazotide acetate

Gap Junction Protein Cytoskeletal Signaling
Larazotide acetate 是合成肽,它起到紧密连接调节器的作用,并将泄漏连接反转到它们的常闭状态。
T10765 Eragidomide

CC-90009,Cereblon modulator 1

Apoptosis; Ligand for E3 Ligase; Molecular Glues Apoptosis; PROTAC
Cereblon modulator 1 是一种 GSPT1 选择性cereblon (CRBN)E3 连接酶调节剂,以分子胶的方式作用。它通过 CRL4CRBN选择性靶向 GSPT1 进行泛素化和蛋白酶体降解。
T29856 Aleplasinin

PAZ 417,PAZ417,PAZ-417

PAI-1 Metabolism
Aleplasinin (PAZ 417) 是纤溶酶原激活物抑制剂 1 (PAI-1) 的选择性和口服活性抑制剂,是纤溶系统的关键负调节剂。 Aleplasinin 可用于阿尔茨海默病研究。
T12896L Shepherdin 79-87 acetate

Shepherdin 79-87 acetate (861224-28-4 free base)

HSP; Survivin Apoptosis; Cytoskeletal Signaling; Metabolism
Shepherdin 79-87 acetate 是 Hsp90 和 survivin 之间复合物的拟肽拮抗剂,survivin 是肿瘤细胞活力的另一个关键调节剂。
T77344 icFSP1

Apoptosis Apoptosis
icFSP1是一种线粒体相关凋亡诱导因子调节剂,具有抗肿瘤活性,可用于研究和治疗肿瘤疾病。
T63806 CFTR corrector 8

CFTR Membrane transporter/Ion channel
CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1].
T5203 Sodium Tartrate

Others Others
Sodium Tartrate 是一种的 pH 调节剂,具有抗氧化活性,能够有效延缓高温加热时的水解,使植物油的酸值增加。
T26955 Cavosonstat

N91115,N 91115,N-91115

GSNOR; CFTR Membrane transporter/Ion channel; Metabolism
Cavosonstat (N91115) 是一种口服活性 S-亚硝基谷胱甘肽还原酶(GSNOR)抑制剂,可促进囊性纤维化跨膜传导调节器(CFTR)成熟和质膜稳定。
T11734 K-80003

TX-803

Akt; RAR/RXR  Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
K-80003(TX-803) 是一种有效的类视黄醇 X 受体α调节剂,对 tRXRα 依赖性的 Akt 激活和肿瘤细胞生长有抑制作用。
T19822 RH-5849

RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine

Others Others
RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) 是一种新型昆虫生长调节剂,可用作控制橄榄果蝇的潜在杀虫剂。
T19821 Methoxyfenozide

Others Others
Methoxyfenozide 是一种二酰基肼类杀虫剂,其与鳞翅类蜕皮激素受体 (EcRs) 结合 (Kd=0.5 nM) 比对二萜 EcRs 结合 (Kd=124 nM) 的选择性高。

化合物

NFAT Transcription Factor Regulator-1
Cat.No: T12218
Synonym:
Target: IL Receptor
STING (WT/R232) activity regulator 126
Cat.No: T60000
Synonym:
Target: STING
KRAS G12D mutation regulator 4
Cat.No: T77804
Synonym:
Target: Others
ER proteostasis regulator-1
Cat.No: T82450
Synonym:
Target: Others
Triflumuron
Cat.No: T5637
Synonym:
Target: Others
Glibenclamide
Cat.No: T1634
Synonym: 格列本脲,Glyburide
Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy
CCG-63808
Cat.No: T14898
Synonym:
Target: GTPase
KM11060
Cat.No: T3135
Synonym:
Target: CFTR, Autophagy
Ataluren
Cat.No: T1805
Synonym: PTC124
Target: CFTR, Autophagy
Halofenozide
Cat.No: T4384
Synonym:
Target: Others
Nesolicaftor
Cat.No: T16681
Synonym: PTI-428
Target: CFTR, Autophagy
GlyH-101
Cat.No: T2451
Synonym: GlyH 101
Target: CFTR, Autophagy
Elexacaftor
Cat.No: T14935
Synonym: VX-445
Target: CFTR, Autophagy
CFTR corrector 2
Cat.No: T5312
Synonym: FDL169
Target: CFTR, Autophagy
Icenticaftor
Cat.No: T9499
Synonym: QBW251
Target: CFTR
GNE-1858
Cat.No: T11438
Synonym:
Target: Others, MAPK
CCG-63802
Cat.No: T14897
Synonym:
Target: GTPase
IOWH-032
Cat.No: T2486
Synonym: IOWH032,IOWH 032
Target: CFTR, Autophagy
Lumacaftor
Cat.No: T2595
Synonym: 鲁玛卡托,VX-809,VRT 826809
Target: CFTR, Autophagy
GLPG1837
Cat.No: T7083
Synonym: ABBV-974
Target: CFTR, Autophagy
Ivacaftor
Cat.No: T2588
Synonym: Ivacaftor (VX-770),VX-770,依伐卡托
Target: CFTR, Autophagy
PPQ-102
Cat.No: T1874
Synonym: PPQ102,CFTR Inhibitor,PPQ 102
Target: CFTR, Autophagy
BPO-27 racemate
Cat.No: T10591
Synonym: BPO-27 (racemate)
Target: CFTR, Autophagy
Tasimelteon
Cat.No: T3495
Synonym: 他司美琼,VEC-162,BMS-214778
Target: Melatonin Receptor, MT Receptor
CFTR(inh)-172
Cat.No: T2355
Synonym: CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172
Target: CFTR, Autophagy
CCG-50014
Cat.No: T6434
Synonym: CCG 50014,4-[(4-氟苯基)甲基]-2-(4-甲基苯基)-1,2,4-噻二唑烷-3,5-二酮
Target: GTPase
Tezacaftor
Cat.No: T2263
Synonym: VX661,1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基乙基)-1H-吲哚-5-基]-环丙烷甲酰胺
Target: CFTR, Autophagy
Hemoregulatory peptide 5b
Cat.No: TP2340
Synonym: hp 5B,Pglu-glu-asp-cys-lys-OH,Peedck,Glp-glu-asp-cys-lys-OH,SP1 Pentapeptide
Target:
DNDS
Cat.No: T20341
Synonym:
Target: CFTR
BIO-32546
Cat.No: T10545
Synonym:
Target: PDE
Folcisteine
Cat.No: T5914
Synonym: 3-Acetylthiazolidine-4-carboxylic acid,半叶素
Target: Others
Walrycin B
Cat.No: T1832
Synonym:
Target: Antibacterial, Antibiotic
WAY-620472
Cat.No: T77612
Synonym:
Target: PPAR
Chlormequat chloride
Cat.No: T20738
Synonym: NSC 34858,NSC34858,EI 38,555,NSC-34858,EI-38,555,矮壮素,EI38,555
Target: Others
Dicyclanil
Cat.No: T5560
Synonym:
Target: Others
Chlorpropham
Cat.No: T7864
Synonym:
Target: Others
DMeOB
Cat.No: T22736
Synonym: 3,3'-Dimethoxybenzaldazine
Target: GluR
P62-mediated mitophagy inducer
Cat.No: T13809
Synonym: PMI
Target: Mitophagy
Valspodar
Cat.No: T17216
Synonym: PSC 833
Target: P-gp
Larazotide acetate
Cat.No: T15711
Synonym:
Target: Gap Junction Protein
Eragidomide
Cat.No: T10765
Synonym: CC-90009,Cereblon modulator 1
Target: Apoptosis, Ligand for E3 Ligase, Molecular Glues
Aleplasinin
Cat.No: T29856
Synonym: PAZ 417,PAZ417,PAZ-417
Target: PAI-1
Shepherdin 79-87 acetate
Cat.No: T12896L
Synonym: Shepherdin 79-87 acetate (861224-28-4 free base)
Target: HSP, Survivin
icFSP1
Cat.No: T77344
Synonym:
Target: Apoptosis
CFTR corrector 8
Cat.No: T63806
Synonym:
Target: CFTR
Sodium Tartrate
Cat.No: T5203
Synonym:
Target: Others
Cavosonstat
Cat.No: T26955
Synonym: N91115,N 91115,N-91115
Target: GSNOR, CFTR
K-80003
Cat.No: T11734
Synonym: TX-803
Target: Akt, RAR/RXR 
RH-5849
Cat.No: T19822
Synonym: RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine
Target: Others
Methoxyfenozide
Cat.No: T19821
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3719 Daminozide

Succinic Acid,DMASA,Aminozide,丁酰肼

Histone Demethylase Chromatin/Epigenetic
Daminozide (Succinic Acid) 是一种植物生长调节剂,选择性地抑制 KDM2/7 JmjC 亚家族,对PHF8、KDM2A 和KIAA1718的IC50值分别为 0.55、1.5 和 2.1 μM。
T3764 1-​Triacontanol

Myricyl alcohol,1-Triacontanol,三十烷醇,Melissyl alcohol,Well-Bloom,Miraculan,Lithospermoside,triacontan-1-ol

Others Others
1-​Triacontanol (Melissyl alcohol) 是天然存在的植物生长调节剂。它是饱和长链醇,能够促进许多植物的生长。
T7220 Prohydrojasmon racemate

Propyl dihydrojasmonate,茉莉酮,Prohydrojasmon

Others Others
Prohydrojasmon racemate (Propyl dihydrojasmonate) 是 Prohydrojasmon 的外消旋体。其中Prohydrojasmon 是合成的植物生长调节剂。
T5571 Forchlorfenuron

氯苯吡脲,氯吡脲,Forchlorfenuron (KT-30, CPPU)

Others Others
Forchlorfenuron (Forchlorfenuron (KT-30, CPPU)) 是一种植物生长调节剂和细胞分裂素,能够增加水果的果实大小,如猕猴桃和葡萄。
T0845 Cyromazine

CGA-72662,Cyromazin,环丙氨嗪

Others; Endogenous Metabolite Metabolism; Others
Cyromazine (CGA-72662) 是三聚氰胺的环丙基衍生物,是昆虫生长调节剂,用作杀虫剂和杀螨剂,通过影响某些昆虫幼虫阶段的神经系统而起作用。
T21205 Ponasterone A

坡那甾酮A,AI3-44686

Others Others
Ponasterone A 是一种蜕皮激素,能够高度亲和蜕皮激素受体。它能够使报告基因能够快速打开和关闭,是细胞和转基因动物中基因表达的有效调节剂。
T5040 Medroxyprogesterone

甲羟孕酮,甲孕酮

Estrogen/progestogen Receptor; Progesterone Receptor Endocrinology/Hormones; Others
Medroxyprogesterone 是一种合成的人孕酮变体,是孕酮受体激动剂,用于治疗肾癌。在兽医实践中用作发情调节剂。
T5293 Maltotriose

D-Maltotriose,麦芽三糖,Amylotriose

Others; Endogenous Metabolite Metabolism; Others
Maltotriose 是一种大肠杆菌麦芽糖调节剂的诱导剂,是酿造中含量第二高的糖。它能够诱导β-半乳糖苷酶合成。
TN2264 Terpinen-4-ol

Terpinine-4-ol,4-萜烯醇,4-Carvomenthenol

Others; Endogenous Metabolite Metabolism; Others
Terpinen-4-ol 是天然单萜,是茶树油的主要生物活性成分。它通过激活的人单核细胞抑制炎症介质的产生,能显著增强多种化疗和生物制剂的疗效。
T6S1657 Paeonolide

Others Others
Paeonolide 是一种广泛存在于 Paeonia 属植物根中的植物糖苷,是骨形成细胞中核心结合因子亚基 α-1 的新型调节剂。
TN2100 Pratensein

红车轴草素,三叶草

Others; NF-κB NF-κB; Others
Pratensein 是黄酮类化合物,能够减少氧化损伤和恢复突触和 BDNF 水平,改善 β-淀粉样蛋白诱导的大鼠认知障碍。
T5086 Pharmatose DCL 14

D-乳糖一水合物,D-Lactose monohydrate

Others; Endogenous Metabolite Metabolism; Others
Pharmatose DCL 14 (D-Lactose monohydrate) 是内源性代谢产物的一种。
T3879 Silychristin

水飞蓟亭,水飞蓟汀,Silicristin

Lipoxygenase Metabolism
Silychristin (Silicristin) 是甲状腺激素转运体MCT8的有效抑制剂,能强烈抑制 T3 的摄取(IC50:110 nM)。它是一种水飞蓟果实中富含的黄酮类化合物,具有抗氧化作用。
T5514 Epibrassinolide

24-Epibrassinolide,B1105,表油菜素内酯,BP55

Apoptosis Apoptosis
Epibrassinolide (BP55) 是一种广泛存在的植物生长激素,具有缓解植物重金属和农药胁迫潜力。它在各种癌细胞中是一种潜在的凋亡诱导剂。
TN6750 2-tert-Butyl-1,4-benzoquinone

Nrf2 Immunology/Inflammation
2-tert-Butyl-1,4-benzoquinone 是丁基化羟基茴香醚 (BHA) 的亲电子代谢物,它在 RAW264.7 细胞中引起 Nrf2 的活化及其负调节剂 Keap1 的 S-芳基化。
T4819 Pipecolic acid

DL-哌啶甲酸,(±)-Piperidine-2-carboxylic acid,呢可酸,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
Pipecolic acid (2-Piperidinecarboxylic acid) 是一种赖氨酸代谢物,是许多微生物次级代谢物的重要前体,可用作吡哆醇依赖性癫痫的诊断标记。
T19458 N-Hydroxypipecolic acid

1-Hydroxy-2-piperidinecarboxylic acid,NHP

Others Others
N-Hydroxypipecolic acid (NHP) 是植物代谢产物和系统性获得性抗性调节剂,可与免疫信号水杨酸协调建立系统性获得性抗性,诱导系统获得性耐药对细菌和卵菌感染。它在植物叶片中系统地积累,以应对病原菌的侵袭。
T5663 α-Lactose

D-乳糖单水合物,Lactose

Others Others
α-Lactose 是牛奶中的主要的糖。它一般以 α 和 β 两个异构体的形式存在,其中α 形式通常以一水合物的形式结晶。
TN1196 17-Hydroxyisolathyrol

Others Others
17-Hydroxyisolathyrol 是一种大环千金子二萜醇衍生物,分离自Euphorbla luthyrrs种子。17-Hydroxyisolathyrol 抑制蛋白质-蛋白质相互作用。
TN1545 D-Tyrosine

Tyrosinase Proteases/Proteasome
D-Tyrosine,是酪氨酸的D异构体,通过抑制酪氨酸酶活性,作为黑色素合成的负向调节剂。此外,D-Tyrosine还能抑制生物膜的形成,并诱导生物膜的自我分散,同时不影响细菌的生长。
T0069 Uracil

Others; Endogenous Metabolite Metabolism; Others
Uracil 是普遍存在的天然嘧啶衍生物,是 RNA 核酸中的四个碱基之一。
T20945 2,4-D

Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。
T3414 Morroniside

莫诺苷,奎宁树

Apoptosis; MMP; Pyroptosis Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T13265 Urolithin B

尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物,具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子,通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性,并抑制 JNK、ERK 和 Akt 的磷酸化,并增强 AMPK 的磷酸化。
TQ0208 SAH

SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸

Others; Endogenous Metabolite Metabolism; Others
SAH (S-Adenosylhomocysteine) 属于氨基酸衍生物,是腺苷和半胱氨酸合成的中间体。SAH 是一种 METTL3-METTL14 异二聚体复合物的抑制剂 (IC50=0.9 µM)。SAH 是多种代谢途径中的调节剂。
T4938 Potassium 1H-indol-3-yl sulfate

硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate

AhR; Endogenous Metabolite Immunology/Inflammation; Metabolism
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) 是人芳烃受体(AhR)的激动剂。芳烃受体(AhR)最近被发现是免疫炎症条件的病理生理调节剂,Potassium 1H-indol-3-yl sulfate 已被证明是AhR的配体。Potassium 1H-indol-3-yl sulfate 也是膳食蛋白质中色氨酸的代谢物。色氨酸被肠道细菌代谢为吲哚,吲哚被吸收到血液中,然后在肝脏中进一步代谢为硫酸吲哚,通常通过尿液排出体外。在肾功能受损的慢性肾病患者中,Potassium 1H-indol-3-yl sulfate 可作为尿毒症毒素在血清中积累,诱导氧化应激并加速疾病进展。250 μM Potassium 1H-indol-3-yl sulfate 可诱导NF-Κb活化,促进大鼠近端小管细胞TGF-β1和Smad3的表达,与促纤维化活性相关。
T3604 Sodium dichloroacetate

Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯

Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
Sodium dichloroacetate (DCA) 是一种肿瘤细胞线粒体中的代谢调节剂,一种丙酮酸脱氢酶激酶 (PDK) 抑制剂。Sodium dichloroacetate 具有抗肿瘤活性,可以降低肿瘤微环境中的乳酸,增加活性氧的产生并促进肿瘤细胞凋亡。
T40450 Dihydrojasmonic acid

Others Others
Dihydrojasmonic acid is a plant growth regulator.
T19457 N-Hydroxypipecolic acid potassium

NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium

Others Others
N-Hydroxypipecolic acid potassium is a metabolite of plant and a systemic acquired resistance (SAR) regulator.
T13503 31-Norlanostenol

Others Others
31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor.
T27807 13-Methyltetradecanoic acid

LeDSF3

Others Others
LeDSF3 is a regulator of the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes and anti-tumor agent. LeDSF3 down-regulates p-AKT and activates caspase-3.
TN7507 (±)-Tuberonic Acid

12-hydroxy Jasmonic Acid

Others Others
(±)-Tuberonic acid, a derivative of the plant growth regulator jasmonic acid, is present in M. oleifera.
TN7503 cis-Zeatin

Others Others
Cis-Zeatin, a cytokinin plant growth regulator and an isomer of trans-zeatin, promotes callus growth in isolated N. tabacum callus tissue at concentrations between 0.1 and 1 µM.
T71795 Norstictic acid

Others Others
Norstic acid是一种有效的选择性变构转录调节剂,显示出抗癌活性、具有抗氧化活性和抗菌活性。
TN1775 Isocryptotanshinone

ERK; JNK; STAT JAK/STAT signaling; MAPK; Stem Cells
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
T73815 TMC-205

Others Others
TMC-205,一种具抗肿瘤细胞增殖活性的天然真菌代谢产物,为SV40启动子的转录上调因子。
T75524 Mutabilol

Others Others
Mutabilol (compound 1) 是一种有效的 p-糖蛋白 (P-gp) 调节剂。Mutabilol 是一种可以从Plectranthus mutabilis 叶中分离得到的天然产物。Mutabilol 增加 NCI-H460/R 细胞中P-gp 的表达。
TN7273 (±)7-epi Jasmonic Acid

2-iso Jasmonic Acid

Others Others
(±)-7-epiJasmonic acid, the primary metabolite in the 12-oxo phytodienoic acid pathway of 13(S)-hydroperoxy linolenic acid metabolism in plants, is synthesized initially as the more active (+)-7-epijasmonic acid. It quickly epimerizes to the more stable (−)-7-jasmonic acid isomer, demonstrating its biological relevance. Acting as a plant growth regulator, (±)-7-epiJasmonic acid triggers various signal transduction pathways, which can either promote growth or inhibit it, likely as a response to s...
TN6198 Mahanine

Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced g
T75600 Coronatine

Others Others
Coronatine 是丁香假单胞菌产生的一种植物生长调节剂。Coronatine 模拟生物活性茉莉酸 (jasmonic acid) 缀合物或高等植物的 octadecanoid 信号分子使植物出现致病症状。Coronatine 通过激活抑制水杨酸 (Salicylic acid) 积累的信号级联,促进植物中丁香假单胞菌的毒力。
T36489 Malformin A

Others Others
Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhibits replication of tobacco mosaic virus (TMV) in local lesion and leaf-disc assays (IC50s = 19.7 and 45.4 μg/ml, respectively). It is cytotoxic to NCI-H460, MIA PaCa-2, MCF-7, SF-268, and WI-38 cancer cells (IC50s = 70, 50, 100, 70, and 100 nM, respectively), inhibits proliferati...

天然产物

Daminozide
Cat.No: T3719
Synonym: Succinic Acid,DMASA,Aminozide,丁酰肼
Target: Histone Demethylase
1-​Triacontanol
Cat.No: T3764
Synonym: Myricyl alcohol,1-Triacontanol,三十烷醇,Melissyl alcohol,Well-Bloom,Miraculan,Lithospermoside,triacontan-1-ol
Target: Others
Prohydrojasmon racemate
Cat.No: T7220
Synonym: Propyl dihydrojasmonate,茉莉酮,Prohydrojasmon
Target: Others
Forchlorfenuron
Cat.No: T5571
Synonym: 氯苯吡脲,氯吡脲,Forchlorfenuron (KT-30, CPPU)
Target: Others
Cyromazine
Cat.No: T0845
Synonym: CGA-72662,Cyromazin,环丙氨嗪
Target: Others, Endogenous Metabolite
Ponasterone A
Cat.No: T21205
Synonym: 坡那甾酮A,AI3-44686
Target: Others
Medroxyprogesterone
Cat.No: T5040
Synonym: 甲羟孕酮,甲孕酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor
Maltotriose
Cat.No: T5293
Synonym: D-Maltotriose,麦芽三糖,Amylotriose
Target: Others, Endogenous Metabolite
Terpinen-4-ol
Cat.No: TN2264
Synonym: Terpinine-4-ol,4-萜烯醇,4-Carvomenthenol
Target: Others, Endogenous Metabolite
Paeonolide
Cat.No: T6S1657
Synonym:
Target: Others
Pratensein
Cat.No: TN2100
Synonym: 红车轴草素,三叶草
Target: Others, NF-κB
Pharmatose DCL 14
Cat.No: T5086
Synonym: D-乳糖一水合物,D-Lactose monohydrate
Target: Others, Endogenous Metabolite
Silychristin
Cat.No: T3879
Synonym: 水飞蓟亭,水飞蓟汀,Silicristin
Target: Lipoxygenase
Epibrassinolide
Cat.No: T5514
Synonym: 24-Epibrassinolide,B1105,表油菜素内酯,BP55
Target: Apoptosis
2-tert-Butyl-1,4-benzoquinone
Cat.No: TN6750
Synonym:
Target: Nrf2
Pipecolic acid
Cat.No: T4819
Synonym: DL-哌啶甲酸,(±)-Piperidine-2-carboxylic acid,呢可酸,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline
Target: Others, Endogenous Metabolite, Antibacterial
N-Hydroxypipecolic acid
Cat.No: T19458
Synonym: 1-Hydroxy-2-piperidinecarboxylic acid,NHP
Target: Others
α-Lactose
Cat.No: T5663
Synonym: D-乳糖单水合物,Lactose
Target: Others
17-Hydroxyisolathyrol
Cat.No: TN1196
Synonym:
Target: Others
D-Tyrosine
Cat.No: TN1545
Synonym:
Target: Tyrosinase
Uracil
Cat.No: T0069
Synonym:
Target: Others, Endogenous Metabolite
2,4-D
Cat.No: T20945
Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸
Target: DNA/RNA Synthesis
Morroniside
Cat.No: T3414
Synonym: 莫诺苷,奎宁树
Target: Apoptosis, MMP, Pyroptosis
Urolithin B
Cat.No: T13265
Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮
Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK
SAH
Cat.No: TQ0208
Synonym: SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸
Target: Others, Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate
Cat.No: T4938
Synonym: 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate
Target: AhR, Endogenous Metabolite
Sodium dichloroacetate
Cat.No: T3604
Synonym: Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯
Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK
Dihydrojasmonic acid
Cat.No: T40450
Synonym:
Target: Others
N-Hydroxypipecolic acid potassium
Cat.No: T19457
Synonym: NHP potassium,1-Hydroxy-2-piperidinecarboxylic acid potassium
Target: Others
31-Norlanostenol
Cat.No: T13503
Synonym:
Target: Others
13-Methyltetradecanoic acid
Cat.No: T27807
Synonym: LeDSF3
Target: Others
(±)-Tuberonic Acid
Cat.No: TN7507
Synonym: 12-hydroxy Jasmonic Acid
Target: Others
cis-Zeatin
Cat.No: TN7503
Synonym:
Target: Others
Norstictic acid
Cat.No: T71795
Synonym:
Target: Others
Isocryptotanshinone
Cat.No: TN1775
Synonym:
Target: ERK, JNK, STAT
TMC-205
Cat.No: T73815
Synonym:
Target: Others
Mutabilol
Cat.No: T75524
Synonym:
Target: Others
(±)7-epi Jasmonic Acid
Cat.No: TN7273
Synonym: 2-iso Jasmonic Acid
Target: Others
Mahanine
Cat.No: TN6198
Synonym:
Target:
Coronatine
Cat.No: T75600
Synonym:
Target: Others
Malformin A
Cat.No: T36489
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00744 CsrA Protein, E. coli, Recombinant

Carbon storage regulator,csrA,Translational reg...

E. coli E. coli
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its f...
TMPY-03185 METRN Protein, Mouse, Recombinant (hFc)

meteorin, glial cell differentiation regulator,Hyra...

Mouse HEK293 Cells
METRN (Meteorin, Glial Cell Differentiation Regulator) is a Protein Coding gene. The encoded protein belongs to the meteorin family. It is broadly expressed in the brain, kidney, and other tissues. Meteorin is a novel secreted protein that is expressed in undifferentiated neural progenitors and the astrocyte lineage, including radial glia. It plays important role in the differentiation of glial cells and also in axonal network formation during neurogenesis. Meteorin selectively promoted astrocyt...
TMPY-03179 CNPY4 Protein, Human, Recombinant (His)

PRAT4B,canopy FGF signaling regulator 4

Human HEK293 Cells
CNPY4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is Q8N129.
TMPY-04918 CNPY4 Protein, Mouse, Recombinant (His)

2610019P18Rik,canopy FGF signaling regulator 4

Mouse HEK293 Cells
CNPY4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q8BQ47.
TMPY-01125 MDMX Protein, Human, Recombinant (His)

MRP1,MDM4, p53 regulator,HDMX,MDMX

Human E. coli
MDM4 (MDM4 Regulator Of P53, also known as MDMX) is a Protein Coding gene. This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus and shows structural similarity to p53-binding protein MDM2. MDM4 is a promising target for cancer therapy, as it is undetectable in most normal adult tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function. MDM4, an essential negative regulator of the P53 tumor ...
TMPH-00660 NikR Protein, E. coli, Recombinant (His)

nikR,Nickel-responsive regulator

E. coli E. coli
Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
TMPY-02714 PRC1 Protein, Human, Recombinant (His)

ASE1,protein regulator of cytokinesis 1

Human Baculovirus Insect Cells
PRC1 (protein regulator of cytokinesis 1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. It is essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. PRC1 is required for KIF14 localization to the central spindle and midbody. It is also required to recruit PLK1 to the spindle. PRC1 stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. It is a homodi...
TMPY-01800 NEGR1 Protein, Mouse, Recombinant (His)

5330422G01Rik,KILON,neuronal growth regulator 1,Ntr...

Mouse HEK293 Cells
NEGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is Q80Z24.
TMPH-01279 CRACR2B Protein, Human, Recombinant (His)

CRACR2B,EFCAB4A,EF-hand calcium-binding domain-containing pr...

Human E. coli
Plays a role in store-operated Ca(2+) entry (SOCE).
TMPH-02020 RGS17 Protein, Human, Recombinant (GST)

Regulator of G-protein signaling 17,RGS17

Human E. coli
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins. R...
TMPY-00226 CNPY3 Protein, Mouse, Recombinant (hFc)

Tnrc5,canopy FGF signaling regulator 3,2410050O22Ri...

Mouse HEK293 Cells
CNPY3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.9 kDa and the accession number is Q9DAU1-1.
TMPH-02227 ERG Protein, Human, Recombinant (His)

Transcriptional regulator ERG,Transforming protein ...

Human P. pastoris (Yeast)
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.6 kDa and the accession number is P11308.
TMPY-03980 ECD Protein, Human, Recombinant (His & GST)

HSGT1,ECD,GCR2,ecdysoneless cell cycle regulator

Human Baculovirus Insect Cells
ECD, also known as ecdysoneless homolog, belongs to the SGT1 family. It is highly expressed in muscle and heart. ECD is a novel promoter of mammalian cell cycle progression. This function is related to its ability to remove the repressive effects of Rb-family tumor suppressors on E2F transcription factors. It is a novel tumor-promoting factor that is differentially expressed in pancreatic cancer and potentially regulates glucose metabolism within cancer cells. ECD may also be a transcriptional ...
TMPY-03964 CGREF1 Protein, Human, Recombinant (His)

CGR11,cell growth regulator with EF-hand domain 1

Human HEK293 Cells
CGREF1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is Q99674-1.
TMPH-02520 BCL2 Protein, Mouse, Recombinant (His)

Bcl2,Apoptosis regulator Bcl-2,Bcl-2

Mouse E. coli
BCL2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P10417.
TMPH-03245 BCL2 Protein, Rat, Recombinant (His)

Bcl2,Apoptosis regulator Bcl-2,Bcl-2

Rat E. coli
BCL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 28.1 kDa and the accession number is P49950.
TMPH-02313 RPGR Protein, Human, Recombinant (hFc)

RPGR,X-linked retinitis pigmentosa GTPase regulator

Human HEK293 Cells
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. May be involved in microtubule organization and regulation of transport in primary cilia.
TMPY-01913 NEGR1 Protein, Human, Recombinant (His)

KILON,IGLON4,DMML2433,Ntra,neuronal growth regulator

Human HEK293 Cells
NEGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.9 kDa and the accession number is Q7Z3B1-1.
TMPY-03261 CNPY2 Protein, Human, Recombinant (His)

canopy FGF signaling regulator 2,HP10390,ZSIG9,MSAP...

Human HEK293 Cells
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and...
TMPY-00138 CNPY3 Protein, Human, Recombinant (hFc)

CAG4A,ERDA5,TNRC5,PRAT4A,canopy FGF signaling regulator<...

Human HEK293 Cells
CNPY3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9BT09-1.
TMPY-05005 CNPY3 Protein, Human, Recombinant (His)

ERDA5,canopy FGF signaling regulator 3,TNRC5,CAG4A,...

Human HEK293 Cells
CNPY3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is A0A7U3JW12.
TMPJ-01192 ELAPOR1 Protein, Human, Recombinant (His)

ELAPOR1,Endosome-Lysosome Associated Apoptosis And Autophagy...

Human HEK293 Cells
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers,but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estr...
TMPY-03395 PC4/SUB1 Protein, Human, Recombinant (His)

PC4,RPO2TC1,SUB1 homolog, transcriptional regulator...

Human E. coli
SUB1 belongs to the transcriptional coactivator PC4 family. It is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SUB1 binds single-stranded DNA. Single-stranded DNA-binding proteins play many roles in nucleic acid metabolism, but their importance during transcription remains unclear. SUB1 exhibits strong genetic interactions with factors necessary for promoter melting. It loc...
TMPH-00535 Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)

Nuclear antigen,Apoptosis regulator BHRF1,Early ant...

EBV E. coli
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell.
TMPH-00659 FlgM Protein, E. coli, Recombinant (His & Myc)

Negative regulator of flagellin synthesis,flgM,Anti...

E. coli E. coli
Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. FlgM Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.8 kDa and the accession number is P0AEM4.
TMPY-00596 CNPY3 Protein, Mouse, Recombinant (His)

Tnrc5,AI413153,2410050O22Rik,canopy FGF signaling regula...

Mouse HEK293 Cells
CNPY3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q9DAU1-1.
TMPH-03177 RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

Elastase modulator,rhlR,Regulatory protein RhlR,HTH...

Pseudomonas aeruginosa E. coli
Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession n...
TMPH-02650 FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)

Fas apoptotic inhibitory molecule 3,Immunoglobulin mu Fc rec...

Mouse E. coli
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
TMPY-02924 RGS1 Protein, Human, Recombinant (His)

1R20,IER1,BL34,HEL-S-87,regulator of G-protein sign...

Human E. coli
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization of T and B cells in lymphoid organs. RGS1 expression may be a prognostic marker for risk stratification and a promising target for the development of a new Multiple myeloma (MM) therapy. The markers in the RGS1 gene might be in linkage disequilibrium with a protective allele that ...
TMPJ-00717 BAG2 Protein, Human, Recombinant (His)

BAG-2,BAG Family Molecular Chaperone Regulator 2,BA...

Human E. coli
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TMPH-00641 YTFE Protein, E. coli, Recombinant (GST)

Regulator of cell morphogenesis and NO signaling,Ir...

E. coli E. coli
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 51.9 kDa and the accession number is P69506.
TMPJ-00584 Bc1-w Protein, Human, Recombinant (His)

Apoptosis Regulator Bcl-W,KIAA0271,Bcl-2-Like Prote...

Human E. coli
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone...
TMPH-01003 ATG14 Protein, Human, Recombinant (His & Myc)

Barkor,Autophagy-related protein 14-like protein,ATG14L,Becl...

Human E. coli
ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5.
TMPY-04058 RGS5 Protein, Human, Recombinant (His)

MST106,MSTP032,MST092,regulator of G-protein signal...

Human E. coli
RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins have recently been identified as signal transduction molecules which have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. The messenger RNA of hRGS5 was abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at l...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His)

Negative regulator of reactive oxygen species,Trans...

Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 acti...
TMPH-02021 RGS2 Protein, Human, Recombinant (His & SUMO)

Regulator of G-protein signaling 2,G0/G1 switch

Human E. coli
RGS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02230 NRROS Protein, Human, Recombinant (His & Myc)

Leucine-rich repeat-containing protein 33,Negative regul...

Human Baculovirus Insect Cells
NRROS Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 73.5 kDa and the accession number is Q86YC3.
TMPH-02231 NRROS Protein, Human, Recombinant (E. coli, His & Myc)

Transforming growth factor beta activator LRRC33,Leucine-ric...

Human E. coli
NRROS Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.5 kDa and the accession number is Q86YC3.
TMPH-02535 BAG3 Protein, Mouse, Recombinant (His & SUMO)

Bcl-2-associated athanogene 3,Bis,BAG-3,BAG family molecular...

Mouse E. coli
BAG3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9JLV1.
TMPH-02534 BAG3 Protein, Mouse, Recombinant (His)

Bcl-2-associated athanogene 3,Bag3,Bcl-2-binding protein Bis...

Mouse P. pastoris (Yeast)
BAG3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9JLV1.
TMPH-02748 KCP Protein, Mouse, Recombinant (His & Myc)

Kcp,Cysteine-rich BMP regulator 2,Kielin/chordin-li...

Mouse E. coli
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. KCP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.7 kDa and the accession number is Q3U492.
TMPH-02159 SMARCC1 Protein, Human, Recombinant (His & SUMO)

SWI/SNF-related matrix-associated actin-dependent regula...

Human E. coli
SMARCC1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.5 kDa and the accession number is Q92922.
TMPH-01208 DEAF1 Protein, Human, Recombinant (His)

SPN,ZMYND5,Suppressin,Zinc finger MYND domain-containing pro...

Human E. coli
DEAF1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 65.4 kDa and the accession number is O75398.
TMPH-02160 SMARCB1 Protein, Human, Recombinant (His)

BRG1-associated factor 47,SNF5 homolog,Integrase interactor ...

Human E. coli
SMARCB1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.0 kDa and the accession number is Q12824.
TMPH-01358 FXYD3 Protein, Human, Recombinant (His & SUMO)

Phospholemman-like,Chloride conductance inducer protein Mat-...

Human E. coli
FXYD3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.5 kDa and the accession number is Q14802.
TMPH-01606 BAG6 Protein, Human, Recombinant (His & Myc)

BAG-6,Protein G3,BAG family molecular chaperone regulato...

Human Baculovirus Insect Cells
BAG6 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P46379.
TMPH-01605 BAG6 Protein, Human, Recombinant (E. coli, His & Myc)

BAT3,BAG6,HLA-B-associated transcript 3,BCL2-associated atha...

Human E. coli
BAG6 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 kDa and the accession number is P46379.
TMPH-01906 SMARCA2 Protein, Human, Recombinant (His & SUMO)

BRG1-associated factor 190B,SNF2-alpha,SWI/SNF-related matri...

Human E. coli
SMARCA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01905 SMARCA2 Protein, Human, Recombinant (His)

Probable global transcription activator SNF2L2,SWI/SNF-relat...

Human P. pastoris (Yeast)
SMARCA2 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02217 SMARCA4 Protein, Human, Recombinant (His)

Transcription activator BRG1,Protein brahma homolog 1,SWI/SN...

Human P. pastoris (Yeast)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating the calcium-dependent release of a repressor compl...
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重组蛋白

CsrA Protein, E. coli, Recombinant
Cat.No: TMPH-00744
Species: E. coli
Expression System: E. coli
METRN Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03185
Species: Mouse
Expression System: HEK293 Cells
CNPY4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03179
Species: Human
Expression System: HEK293 Cells
CNPY4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04918
Species: Mouse
Expression System: HEK293 Cells
MDMX Protein, Human, Recombinant (His)
Cat.No: TMPY-01125
Species: Human
Expression System: E. coli
NikR Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00660
Species: E. coli
Expression System: E. coli
PRC1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02714
Species: Human
Expression System: Baculovirus Insect Cells
NEGR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01800
Species: Mouse
Expression System: HEK293 Cells
CRACR2B Protein, Human, Recombinant (His)
Cat.No: TMPH-01279
Species: Human
Expression System: E. coli
RGS17 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02020
Species: Human
Expression System: E. coli
CNPY3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00226
Species: Mouse
Expression System: HEK293 Cells
ERG Protein, Human, Recombinant (His)
Cat.No: TMPH-02227
Species: Human
Expression System: P. pastoris (Yeast)
ECD Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-03980
Species: Human
Expression System: Baculovirus Insect Cells
CGREF1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03964
Species: Human
Expression System: HEK293 Cells
BCL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02520
Species: Mouse
Expression System: E. coli
BCL2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03245
Species: Rat
Expression System: E. coli
RPGR Protein, Human, Recombinant (hFc)
Cat.No: TMPH-02313
Species: Human
Expression System: HEK293 Cells
NEGR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01913
Species: Human
Expression System: HEK293 Cells
CNPY2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03261
Species: Human
Expression System: HEK293 Cells
CNPY3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00138
Species: Human
Expression System: HEK293 Cells
CNPY3 Protein, Human, Recombinant (His)
Cat.No: TMPY-05005
Species: Human
Expression System: HEK293 Cells
ELAPOR1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01192
Species: Human
Expression System: HEK293 Cells
PC4/SUB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03395
Species: Human
Expression System: E. coli
Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)
Cat.No: TMPH-00535
Species: EBV
Expression System: E. coli
FlgM Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00659
Species: E. coli
Expression System: E. coli
CNPY3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00596
Species: Mouse
Expression System: HEK293 Cells
RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03177
Species: Pseudomonas aeruginosa
Expression System: E. coli
FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02650
Species: Mouse
Expression System: E. coli
RGS1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02924
Species: Human
Expression System: E. coli
BAG2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00717
Species: Human
Expression System: E. coli
YTFE Protein, E. coli, Recombinant (GST)
Cat.No: TMPH-00641
Species: E. coli
Expression System: E. coli
Bc1-w Protein, Human, Recombinant (His)
Cat.No: TMPJ-00584
Species: Human
Expression System: E. coli
ATG14 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01003
Species: Human
Expression System: E. coli
RGS5 Protein, Human, Recombinant (His)
Cat.No: TMPY-04058
Species: Human
Expression System: E. coli
NRROS Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02803
Species: Mouse
Expression System: E. coli
RGS2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02021
Species: Human
Expression System: E. coli
NRROS Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02230
Species: Human
Expression System: Baculovirus Insect Cells
NRROS Protein, Human, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-02231
Species: Human
Expression System: E. coli
BAG3 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02535
Species: Mouse
Expression System: E. coli
BAG3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02534
Species: Mouse
Expression System: P. pastoris (Yeast)
KCP Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02748
Species: Mouse
Expression System: E. coli
SMARCC1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02159
Species: Human
Expression System: E. coli
DEAF1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01208
Species: Human
Expression System: E. coli
SMARCB1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02160
Species: Human
Expression System: E. coli
FXYD3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01358
Species: Human
Expression System: E. coli
BAG6 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01606
Species: Human
Expression System: Baculovirus Insect Cells
BAG6 Protein, Human, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-01605
Species: Human
Expression System: E. coli
SMARCA2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01906
Species: Human
Expression System: E. coli
SMARCA2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01905
Species: Human
Expression System: P. pastoris (Yeast)
SMARCA4 Protein, Human, Recombinant (His)
Cat.No: TMPH-02217
Species: Human
Expression System: P. pastoris (Yeast)
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Cat. No. Product Name Target Signaling Pathways
T27098 Ivacaftor-D9

deutivacaftor,CTP-656

CTP-656, a cystic fibrosis transmembrane conductance regulator (CFTR) channel activator, is used potentially for the treatment of cystic fibrosis.
TMIJ-0457 Daminozide-d6 (dimethyl-d6)

Daminozide-d6 (dimethyl-d6) 是 Daminozide 的氘代化合物。Daminozide 的 CAS 号为 1596-84-5。Daminozide 是一种植物生长调节剂,选择性地抑制 KDM2/7 JmjC 亚家族,对PHF8、KDM2A和KIAA1718的IC50值分别为 0.55、1.5 和 2.1 μM。
TMIH-0568 Tezacaftor-d4

VX-661-d4

Tezacaftor-d4 是 Tezacaftor 的氘代化合物。Tezacaftor 的 CAS 号为 1152311-62-0。VX-661 是一种小分子,可用作囊性纤维化跨膜电导调节器基因功能的校正剂。
TMID-0239 Forchlorfenuron-d5

Forchlorfenuron-d5 是 Forchlorfenuron 的氘代化合物。Forchlorfenuron 的 CAS 号为 68157-60-8。Forchlorfenuron 是一种植物生长调节剂和细胞分裂素,能够增加水果的果实大小,如猕猴桃和葡萄。
TMID-0133 Medroxyprogesterone-d3

Medroxyprogesterone-d3 是 Medroxyprogesterone 的氘代化合物。Medroxyprogesterone 的 CAS 号为 520-85-4。Medroxyprogesterone 是一种合成的人孕酮变体,是孕酮受体激动剂,用于治疗肾癌。在兽医实践中用作发情调节剂。
TMIJ-0417 2,4-D-d3

2,4-D-d3 是 2,4-D 的氘代化合物。2,4-D 的 CAS 号为 94-75-7。2,4-Dichlorophenoxyacetic acid 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。
TMIH-0109 Bempedoic acid-d4

Bempedoic acid-d4 是 Bempedoic acid 的氘代化合物。Bempedoic acid 的 CAS 号为 738606-46-7。ETC-1002 是一种 ATP-柠檬酸裂解酶抑制剂,可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T71303 Flufenamic Acid-d4

Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 µM for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear...

同位素标记化合物

Ivacaftor-D9
Cat.No: T27098
Synonym: deutivacaftor,CTP-656
Target:
Daminozide-d6 (dimethyl-d6)
Cat.No: TMIJ-0457
Synonym:
Target:
Tezacaftor-d4
Cat.No: TMIH-0568
Synonym: VX-661-d4
Target:
Forchlorfenuron-d5
Cat.No: TMID-0239
Synonym:
Target:
Medroxyprogesterone-d3
Cat.No: TMID-0133
Synonym:
Target:
2,4-D-d3
Cat.No: TMIJ-0417
Synonym:
Target:
Bempedoic acid-d4
Cat.No: TMIH-0109
Synonym:
Target:
Flufenamic Acid-d4
Cat.No: T71303
Synonym:
Target:
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