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Search Results for " ractrans4hydroxy glyburide "
Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T35635 rac-trans-4-hydroxy Glyburide

Others Others
rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide .1,2It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.1rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50values of 0.95 and 100 nM, respectively.2 1.Zharikova, O.L., Fokina, V.M., Nanovskaya, T.N., et al.Identification of the major human hepatic and placental enzymes ...

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rac-trans-4-hydroxy Glyburide
Cat.No: T35635
Synonym:
Target: Others
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