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Targets Recommended: Others

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11861 LM11A-31 dihydrochloride

Others Others
LM11A-31 dihydrochloride 是一种具有高血脑屏障通透性的氨基酸衍生物,能阻断 p75 介导的细胞死亡。它是一种 p75NTR(神经营养蛋白受体 p75) 非肽调节剂,是口服有效的 proNGF 拮抗剂。它可以逆转中晚期的阿尔茨海默氏病小鼠模型中的胆碱能神经突营养不良。
T12669 (Rac)-LM11A-31 dihydrochloride

Others Others
(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride is a potent antagonist of proNGF (nerve growth factor).

化合物

LM11A-31 dihydrochloride
Cat.No: T11861
Synonym:
Target: Others
(Rac)-LM11A-31 dihydrochloride
Cat.No: T12669
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-01468 pro-Beta NGF Protein, Human, Recombinant

β-NGF,NGF,NGFB,Beta-NGF,Beta-Nerve Growth Factor,pro-Beta NG...

Human E. coli
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.

重组蛋白

pro-Beta NGF Protein, Human, Recombinant
Cat.No: TMPJ-01468
Species: Human
Expression System: E. coli
TargetMol Loading
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