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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37331 |
Pyrrophenone
|
Others | Others |
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01911 |
PLA2G1B Protein, Mouse, Recombinant (His)
Pla2a,sPLA2IB,phospholipase |
Mouse | HEK293 Cells |
PLA2G1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.3 kDa and the accession number is Q9Z0Y2. | |||
TMPY-01689 |
PLA2G1B Protein, Human, Recombinant (His)
PLA2,PPLA2,phospholipase A2 |
Human | HEK293 Cells |
PLA2G1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is P04054. |