Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12351 |
p53 and MDM2 proteins-interaction-inhibitor (racemic)
p53-and-mdm2-proteins-interaction-inhibitor-racemic |
Others | Others |
p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins. | |||
T12350 |
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
|
Others | Others |
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a interaction inhibitor between p53 and MDM2 proteins. | |||
T78699 |
MDMX/MDM2-IN-2
|
Others | Others |
MDMX/MDM2-IN-2 是一款p53-MDM2/MDMX双重抑制剂,具有高效性,其对MDM2和MDMX的Ki值分别为0.23 μM和2.45 μM。该化合物阻断p53与MDM2蛋白的相互作用,从而恢复p53功能,诱导细胞周期停滞与细胞凋亡。同时,MDMX/MDM2-IN-2抑制细胞迁移和侵袭,显示出潜在的抗肿瘤活性。 |