Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01239 |
XPC Protein, Human, Recombinant (His)
Xeroderma pigmentosum group C-complementing protein,p125... |
Human | E. coli |
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein i... |