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Search Results for " oxygenase-1 "
Targets Recommended: Reactive Oxygen Species

25

抑制剂 & 化合物

10

天然产物

1735

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T11580 Heme Oxygenase-1-IN-1

HO-1-IN-1

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Heme Oxygenase-1-IN-1 (HO-1-IN-1) 是一种血红素加氧酶 1 (HO-1) 抑制剂,IC50=250 nM。
T11580L Heme Oxygenase-1-IN-1 hydrochloride

HO-1-IN-1 hydrochloride

Others Others
HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).
T13396 Zinc Protoporphyrin

Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX

Apoptosis; Reactive Oxygen Species; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) 是一种具有口服活性的,竞争性血红素加氧酶-1 抑制剂,显著减弱间苯三酚对 H2O2 的保护作用,具有抗癌活性。它用于评估人群铁状态与血红蛋白浓度的组合,也可用作个体孕妇和儿童缺铁的筛查标志物。
T61078 Heme Oxygenase-1-IN-2

Others Others
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.
T60847 Heme Oxygenase-2-IN-1

Others Others
Heme Oxygenase-2-IN-1 (Compound 9) 是血红素加氧酶 (HO-2) 的选择性抑制剂。Heme Oxygenase-2-IN-1 对 HO-1和HO-2 的IC50值分别为 14.9 μM 和0.9 μM。
T3459 VK3-OCH3

2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na

Others Others
VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) 是一种通过血红素加氧酶(HO-1) 相关机制的选择性抗肿瘤剂;维生素 K3 类似物。
T4977 Sofalcone

索法酮,SU-88

Antibacterial; Autophagy Autophagy; Microbiology/Virology
Sofalcone (SU-88) 可诱导血红素加氧酶-1在胃肠上皮中的表达,是一种抗胃溃疡剂。
T75098 HIF-PHD-IN-3

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
HIF-PHD-IN-3 是一种有效的 hiPSC-CM 心脏保护支架,对 HIF-PHD 有潜在的抑制作用,可调节血红素加氧酶-1,可用于研究贫血。
T0839L S-(+)-Ketoprofen

RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen,(S)-(+)-酮洛芬,右旋酮洛芬

COX Immunology/Inflammation; Neuroscience
S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) 抑制 COX-1和 COX-2的IC50值分别为 1.9 和 27 nM。
T27064 CP-312

CP312,Cardioprotectant 312

Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
CP-312 (Cardioprotectant 312)是一种抗氧化防御反应激活剂,它通过诱导血红素加氧酶-1发挥作用,通过诱导 HMOX1 表达来靶向抗氧化反应网络,从而保护 hiPSC-CM 的活力。CP-312 保护人 iPSC 衍生的心肌细胞免受氧化应激。
T36113 Cobaltic Protoporphyrin IX chloride

Protoporphyrin IX cobaltic chloride

Autophagy Autophagy
Cobaltic Protoporphyrin IX chloride (CoPP)是一种有效的血红素加氧酶 1(HO-1)诱导剂,具有抗病毒活性,通过诱导 I 型 IFN 反应来抑制甲型流感病毒(IAV)感染。
T1394 Ibuprofen

Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil

COX Immunology/Inflammation; Neuroscience
Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID),具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂,IC50值分别为 13 和 370 μM,导致前列腺素和血栓素前体的形成减少。
T0839 Ketoprofen

酮基布洛芬,RP-19583,酮洛芬

Apoptosis; COX; MRP Apoptosis; Immunology/Inflammation; Neuroscience
Ketoprofen (RP-19583) 是一种非甾体抗炎剂,能够有效地抑制COX 的活性,在人血单核细胞中,对 COX-1 和 COX-2 的IC50值分别为 2 nM 和 26 nM。
T70901 QC-308 HCl

Others Others
QC-308 HCl is a novel Heme Oxygenase-1 Inhibitor (HO-1 IC50=0.27μM; HO-2 IC50=0.46μM).
T68288 OB-24 free base

Others Others
OB-24 free base is a potent and selective heme oxygenase 1 (HO-1) inhibitor.
T30681 CABP

2-CABP,2CABP,2 CABP

Others Others
CABP is a transition analog of ribulos-1, 5-diphosphate carboxylase/oxygenase (Rubisco).
T13524 9-cis-β-Carotene

Others Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo.
T73666 Proglumetacin

Others Others
Proglumetacin 是一种口服有效的环加氧酶 (cyclo-oxygenase) 抑制剂。Proglumetacin 可以抑制 SARS-CoVMpro(新冠病毒的主要蛋白酶),其 AC50为 8.9 μM。Proglumetacin 具有抗炎活性,可用于炎症(如类风湿关节炎、过敏性气囊炎)的研究。
T78623 Cobalt protoporphyrin IX

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Cobalt protoporphyrin IX 作为一种特异性的血红素加氧酶-1 (HO-1) 诱导剂,表现出对甲型流感病毒 (IAV) 的广谱抗病毒活性。
T63075 ALOX15-IN-1

Others Others
ALOX15-IN-1 (compound 8b) 是一种选择性的、有效的兔和人 ALOX15 亚油酸加氧酶 (linoleate oxygenase) 活性抑制剂,能够作用于 ALOX15 直系同源物亚油酸 (LA) (IC50: 0.04 μM) 和花生四烯酸 (AA) (IC50: 2.06 μM)。
T41175 OB 24 hydrochloride

Others Others
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
T78508 Delmitide acetate

RDP-58 acetate

IFNAR Immunology/Inflammation
Delmitide acetate (RDP58) 是一种 d-异构体十肽,具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成,同时提高血红素加氧酶 1 的活性,可用于针对溃疡性结肠炎的研究。
T74600 Keap1-Nrf2-IN-9

Others Others
Keap1-Nrf2-IN-9(compound 11)是一种有效Keap1-Nrf2PPI抑制剂,IC50为0.575 µM。该化合物能够提升Nrf2靶基因表达,涉及血红素加氧酶1 (Hmox1)、谷胱甘肽S转移酶P (GstP) 以及谷氨酸-半胱氨酸连接酶的催化(Gclc)与调节(Gclm)亚基。在ARPE19细胞中,Keap1-Nrf2-IN-9展现出无细胞毒活性。
T75238 YS-49 monohydrate

Others Others
YS-49 (单水合物) 作为PI3K/Akt(RhoA的下游靶点)的激活剂,有效降低3-甲基胆碱处理的细胞中RhoA/PTEN的活性。此外,YS-49通过促进血红素加氧酶(HO-1)的表达,抑制血管紧张素II(Ang II)诱导的血管平滑肌细胞(VSMC)增殖。作为一种异喹啉化合物生物碱,YS-49因激活心脏β-adrenoceptors而显示出显著的正性肌力效应。
TP2109 TAT 14

Nrf2 Immunology/Inflammation
TAT-14 是 由14 个氨基酸组成的多肽,是 Nrf2激活因子,表现出抗炎活性。它通过靶向 Nrf2 上 Keap1 的结合位点而非 Nrf2 mRNA 表达来提高 Nrf2 蛋白水平。

化合物

Heme Oxygenase-1-IN-1
Cat.No: T11580
Synonym: HO-1-IN-1
Target: Reactive Oxygen Species
Heme Oxygenase-1-IN-1 hydrochloride
Cat.No: T11580L
Synonym: HO-1-IN-1 hydrochloride
Target: Others
Zinc Protoporphyrin
Cat.No: T13396
Synonym: Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite
Heme Oxygenase-1-IN-2
Cat.No: T61078
Synonym:
Target: Others
Heme Oxygenase-2-IN-1
Cat.No: T60847
Synonym:
Target: Others
VK3-OCH3
Cat.No: T3459
Synonym: 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na
Target: Others
Sofalcone
Cat.No: T4977
Synonym: 索法酮,SU-88
Target: Antibacterial, Autophagy
HIF-PHD-IN-3
Cat.No: T75098
Synonym:
Target: Reactive Oxygen Species
S-(+)-Ketoprofen
Cat.No: T0839L
Synonym: RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen,(S)-(+)-酮洛芬,右旋酮洛芬
Target: COX
CP-312
Cat.No: T27064
Synonym: CP312,Cardioprotectant 312
Target: Reactive Oxygen Species, Autophagy
Cobaltic Protoporphyrin IX chloride
Cat.No: T36113
Synonym: Protoporphyrin IX cobaltic chloride
Target: Autophagy
Ibuprofen
Cat.No: T1394
Synonym: Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil
Target: COX
Ketoprofen
Cat.No: T0839
Synonym: 酮基布洛芬,RP-19583,酮洛芬
Target: Apoptosis, COX, MRP
QC-308 HCl
Cat.No: T70901
Synonym:
Target: Others
OB-24 free base
Cat.No: T68288
Synonym:
Target: Others
CABP
Cat.No: T30681
Synonym: 2-CABP,2CABP,2 CABP
Target: Others
9-cis-β-Carotene
Cat.No: T13524
Synonym:
Target: Others
Proglumetacin
Cat.No: T73666
Synonym:
Target: Others
Cobalt protoporphyrin IX
Cat.No: T78623
Synonym:
Target: Reactive Oxygen Species
ALOX15-IN-1
Cat.No: T63075
Synonym:
Target: Others
OB 24 hydrochloride
Cat.No: T41175
Synonym:
Target: Others
Delmitide acetate
Cat.No: T78508
Synonym: RDP-58 acetate
Target: IFNAR
Keap1-Nrf2-IN-9
Cat.No: T74600
Synonym:
Target: Others
YS-49 monohydrate
Cat.No: T75238
Synonym:
Target: Others
TAT 14
Cat.No: TP2109
Synonym:
Target: Nrf2
Cat. No. Product Name Target Signaling Pathways
TN3694 Coniferaldehyde

NOS; COX; Nrf2; PKC; Autophagy Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience
Coniferaldehyde 能显着抑制酒球菌菌株的生长活力。 Coniferaldehyde 通过诱导血红素加氧酶 1 (HO-1) 发挥抗炎特性。
T6S1302 Carnosol

Nrf2; Endogenous Metabolite; S6 Kinase Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling
Carnosol 是 Nrf2激活剂,增加 Nrf2 的水平以及能促进血红素氧合酶 1(HMOX1) 表达。它是核糖体 S6激酶(RSK2)抑制剂,可用于胃癌相关研究,IC50值约为 5.5 μM。
T6S1027 Tussilagone

Others Others
Tussilagone 是Tussilago farfara 的主要活性成分,具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应,提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。
T5515 Hemin

氯化血红素,Hemin chloride

Mitophagy; Ferroptosis; Autophagy Apoptosis; Autophagy
Hemin (Hemin chloride) 是一种含有氯的含铁卟啉,一种血红素加氧酶 (HO)-1 诱导剂。Hemin 对卟啉病具有治疗活性,可以减少患者的血红素缺乏,从而通过生物化学反馈抑制 δ-氨基乙酰丙酸合成酶的活性。
T4868 gamma-Linolenic acid

gamolenic acid,γ-Linolenic acid,γ-亚麻酸

Endogenous Metabolite Metabolism
gamma-Linolenic acid (gamolenic acid) 是一种 omega-6 (n-6),18 碳 (18C-) 多不饱和脂肪酸 (PUFA),可以从人乳和植物种子油中提取。
T6429 Caffeic Acid Phenethyl Ester

Phenylethyl Caffeate,咖啡酸苯乙酯,CAPE

Apoptosis; NF-κB Apoptosis; NF-κB
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) 是咖啡酸的苯乙醇酯,是蜂巢蜂胶的生物活性成分。它抑制核转录因子 NF-kappa B 的激活,具有抗肿瘤、细胞保护和免疫调节活性。它抑制 PDGF 诱导的血管平滑肌细胞增殖。
T2915 Bardoxolone

RTA 401,齐墩果烷三萜化合物,CDDO

Others; Nrf2 Immunology/Inflammation; Others
Bardoxolone (CDDO) 是新型核调节因子激活剂。
TN3057 4-O-Methylbutein

Autophagy Autophagy
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of HO-1 has proven to be a useful tool for fighting inflammation.
TN4420 Latifolin

檀木

IL Receptor; IκB/IKK; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Antifection; Autophagy Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi.
TN4064 Flavoglaucin

Phosphatase; IL Receptor; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Autophagy Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammato

天然产物

Coniferaldehyde
Cat.No: TN3694
Synonym:
Target: NOS, COX, Nrf2, PKC, Autophagy
Carnosol
Cat.No: T6S1302
Synonym:
Target: Nrf2, Endogenous Metabolite, S6 Kinase
Tussilagone
Cat.No: T6S1027
Synonym:
Target: Others
Hemin
Cat.No: T5515
Synonym: 氯化血红素,Hemin chloride
Target: Mitophagy, Ferroptosis, Autophagy
gamma-Linolenic acid
Cat.No: T4868
Synonym: gamolenic acid,γ-Linolenic acid,γ-亚麻酸
Target: Endogenous Metabolite
Caffeic Acid Phenethyl Ester
Cat.No: T6429
Synonym: Phenylethyl Caffeate,咖啡酸苯乙酯,CAPE
Target: Apoptosis, NF-κB
Bardoxolone
Cat.No: T2915
Synonym: RTA 401,齐墩果烷三萜化合物,CDDO
Target: Others, Nrf2
4-O-Methylbutein
Cat.No: TN3057
Synonym:
Target: Autophagy
Latifolin
Cat.No: TN4420
Synonym: 檀木
Target: IL Receptor, IκB/IKK, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Antifection, Autophagy
Flavoglaucin
Cat.No: TN4064
Synonym:
Target: Phosphatase, IL Receptor, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Autophagy
Cat. No. Product Name Species Expression System
TMPJ-00817 HO-1 Protein, Human, Recombinant

HO,HMOX1,HO-1,Heme Oxygenase ...

Human E. coli
Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy me...
TMPH-01432 HMOX1 Protein, Human, Recombinant (His)

HMOX1,Heme oxygenase 1

Human E. coli
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. HMOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHi...
TMPY-02519 BLVRB Protein, Human, Recombinant (His)

HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U...

Human E. coli
Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc)

1810061I13Rik,Clec2,C-ty...

Mouse HEK293 Cells
CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1.
TMPY-00986 IL-34 Protein, Mouse, Recombinant (His)

interleukin 34,2010004A03Rik,AI593503

Mouse HEK293 Cells
IL-34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q8R1R4-1.
TMPY-00991 LIFR Protein, Human, Recombinant (His)

STWS,CD118,SJS2,LIF-R,leukemia inhibitory ...

Human HEK293 Cells
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1.
TMPY-02412 ENO1 Protein, Human, Recombinant (His)

PPH,NNE,enolase 1, (alpha),ENO1L1...

Human E. coli
ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1.
TMPY-03956 Fas Ligand Protein, Human, Recombinant (His)

TNLG1A,FASL,FASLG,CD178,CD95-L,APT1

Human P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei...
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)

hIRE1p,endoplasmic reticulum to nucleus signaling <...

Human Baculovirus Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1.
TMPY-03363 C-Reactive Protein Protein, Human, Recombinant

C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...

Human HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPY-01349 ICAM-1/CD54 Protein, Mouse, Recombinant (His)

MALA-2,Ly-47,CD54,intercellular adhesion molecule 1...

Mouse HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
TMPY-04212 IL-16 Protein, Mouse, Recombinant (His)

白介素,interleukin 16,mKIAA4048,白细胞介素

Mouse E. coli
IL-16 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.5 kDa and the accession number is O54824-1.
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His)

PRO2275,SerpinA1,serpin peptidase inhibitor, clade ...

Human HEK293 Cells
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1.
TMPY-05354 CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD28 molecule,Tp44

Human HEK293 Cells
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is P10747-1.
TMPY-01139 PDGFRA Protein, Human, Recombinant (His)

PDGFR-2,CD140A,RHEPDGFRA,platelet-derived growth fa...

Human HEK293 Cells
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1...

Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-02617 Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)

NP Protein

H2N2 Baculovirus Insect Cells
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P21433-1.
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

angiopoietin 1,AGPT,AGP1,ANG1

Human HEK293 Cells
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1.
TMPY-01853 SIRP gamma Protein, Human, Recombinant (His)

bA77C3.1,signal-regulatory protein gamma,SIRP γ/SIR...

Human HEK293 Cells
SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1.
TMPY-06051 SIRP alpha Protein, Human, Recombinant (hFc)

signal-regulatory protein alpha,SIRP alpha,PTPNS1,P...

Human HEK293 Cells
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1.
TMPY-01701 IL-12RB1 Protein, Human, Recombinant (His)

interleukin 12 receptor, β1,IL12R...

Human HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1.
TMPY-04782 LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)

LIR6,leukocyte immunoglobulin like receptor A1,LIR-...

Human HEK293 Cells
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is O75019-1.
TMPY-01907 VSIG4 Protein, Human, Recombinant (His)

Z39IG,CRIg,V-set and immunoglobulin domain containing 4

Human HEK293 Cells
VSIG4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9Y279-1.
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

interleukin 11 receptor subunit alpha,hCG_...

Human HEK293 Cells
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1.
TMPY-00828 Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)

MPS2,IDS,SIDS,iduronate 2-sulfatase

Human HEK293 Cells
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an...
TMPY-01834 CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)

CD16,Fc receptor, IgG, low affinity III

Mouse HEK293 Cells
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is P08508-1.
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His)

CD123,interleukin 3 receptor, alpha (low affinity),...

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1.
TMPY-03273 IL-18 Protein, Mouse, Recombinant

interleukin 18,白细胞介素,白介素,Il-18,Igif

Mouse E. coli
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1.
TMPY-01431 L1CAM Protein, Human, Recombinant (His)

N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu...

Human HEK293 Cells
L1CAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 125 kDa and the accession number is P32004-1.
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

PRR1,ED4,PVRR,nectin-1,OFC7,SK-12...

Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1.
TMPY-05030 PCDH7 Protein, Human, Recombinant (His)

BHPCDH

Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number...
TMPY-04810 CD47 Protein, Mouse, Recombinant (His)

AA407862,CD47 molecule,AW108519,91

Mouse HEK293 Cells
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q61735-1.
TMPY-06076 LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like...

Human HEK293 Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPY-01298 CADM1 Protein, Human, Recombinant (His)

Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-

Human HEK293 Cells
CADM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9BY67-1.
TMPY-02154 FAP Protein, Human, Recombinant (His)

fibroblast activation protein, alpha,Fibroblast Activation P...

Human HEK293 Cells
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1.
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His)

HPT-1,cadherin 17, LI cadherin (liver-inte...

Human HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1.
TMPY-01608 Decorin Protein, Human, Recombinant (His)

PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII

Human HEK293 Cells
Decorin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P07585-1.
TMPY-01573 SIRP alpha Protein, Human, Recombinant (G75A, His)

PTPNS1,signal-regulatory protein alpha,SIRP,MYD-

Human HEK293 Cells
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1.
TMPY-04779 BTN3A2 Protein, Human, Recombinant (His)

BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...

Human HEK293 Cells
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted...
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

p60,TNFR60,TNFAR,TBP1,CD120a,TNFR1

Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPY-01055 IL-4R Protein, Human, Recombinant (His)

interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA

Human HEK293 Cells
IL-4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.18 kDa and the accession number is P24394-1.
TMPY-02105 SCF Protein, Mouse, Recombinant (His)

Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con

Mouse Baculovirus Insect Cells
SCF Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is P20826-1.
TMPY-04793 IL-35 Protein, Human, Recombinant (Flag & His)

NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NFSK,IL-

Human HEK293 Cells
IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1.
TMPY-05277 IL-4R Protein, Human, Recombinant (hFc)

IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor

Human HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1.
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

Angiopoietin-2,AGPT2,angiopoietin 2,ANG2

Human HEK293 Cells
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is O15123-1.
TMPY-04483 IRAK4 Protein, Human, Recombinant (His)

IPD1,NY-REN-64,REN64,interleukin-1 recepto...

Human Baculovirus Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
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重组蛋白

HO-1 Protein, Human, Recombinant
Cat.No: TMPJ-00817
Species: Human
Expression System: E. coli
HMOX1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01432
Species: Human
Expression System: E. coli
BLVRB Protein, Human, Recombinant (His)
Cat.No: TMPY-02519
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
CLEC-2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00586
Species: Mouse
Expression System: HEK293 Cells
IL-34 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00986
Species: Mouse
Expression System: HEK293 Cells
LIFR Protein, Human, Recombinant (His)
Cat.No: TMPY-00991
Species: Human
Expression System: HEK293 Cells
ENO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02412
Species: Human
Expression System: E. coli
Fas Ligand Protein, Human, Recombinant (His)
Cat.No: TMPY-03956
Species: Human
Expression System: P. pastoris (Yeast)
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
Cat.No: TMPY-04413
Species: Human
Expression System: Baculovirus Insect Cells
C-Reactive Protein Protein, Human, Recombinant
Cat.No: TMPY-03363
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01349
Species: Mouse
Expression System: HEK293 Cells
IL-16 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04212
Species: Mouse
Expression System: E. coli
Serpin A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00915
Species: Human
Expression System: HEK293 Cells
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05354
Species: Human
Expression System: HEK293 Cells
PDGFRA Protein, Human, Recombinant (His)
Cat.No: TMPY-01139
Species: Human
Expression System: HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04956
Species: Human
Expression System: HEK293 Cells
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
Cat.No: TMPY-02617
Species: H2N2
Expression System: Baculovirus Insect Cells
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05435
Species: Human
Expression System: HEK293 Cells
SIRP gamma Protein, Human, Recombinant (His)
Cat.No: TMPY-01853
Species: Human
Expression System: HEK293 Cells
SIRP alpha Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06051
Species: Human
Expression System: HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01701
Species: Human
Expression System: HEK293 Cells
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)
Cat.No: TMPY-04782
Species: Human
Expression System: HEK293 Cells
VSIG4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01907
Species: Human
Expression System: HEK293 Cells
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
Cat.No: TMPY-01462
Species: Human
Expression System: HEK293 Cells
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
Cat.No: TMPY-00828
Species: Human
Expression System: HEK293 Cells
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
Cat.No: TMPY-01834
Species: Mouse
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
Cat.No: TMPY-01410
Species: Human
Expression System: HEK293 Cells
IL-18 Protein, Mouse, Recombinant
Cat.No: TMPY-03273
Species: Mouse
Expression System: E. coli
L1CAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01431
Species: Human
Expression System: HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05579
Species: Human
Expression System: HEK293 Cells
PCDH7 Protein, Human, Recombinant (His)
Cat.No: TMPY-05030
Species: Human
Expression System: Baculovirus Insect Cells
CD47 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04810
Species: Mouse
Expression System: HEK293 Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06076
Species: Human
Expression System: HEK293 Cells
CADM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01298
Species: Human
Expression System: HEK293 Cells
FAP Protein, Human, Recombinant (His)
Cat.No: TMPY-02154
Species: Human
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPY-01912
Species: Human
Expression System: HEK293 Cells
Decorin Protein, Human, Recombinant (His)
Cat.No: TMPY-01608
Species: Human
Expression System: HEK293 Cells
SIRP alpha Protein, Human, Recombinant (G75A, His)
Cat.No: TMPY-01573
Species: Human
Expression System: HEK293 Cells
BTN3A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04779
Species: Human
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
Cat.No: TMPY-01459
Species: Human
Expression System: HEK293 Cells
IL-4R Protein, Human, Recombinant (His)
Cat.No: TMPY-01055
Species: Human
Expression System: HEK293 Cells
SCF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02105
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-35 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-04793
Species: Human
Expression System: HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05277
Species: Human
Expression System: HEK293 Cells
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00664
Species: Human
Expression System: HEK293 Cells
IRAK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04483
Species: Human
Expression System: Baculovirus Insect Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0207 (S)-Ketoprofen-d3

(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。
TMIJ-0342 Aniline-d5

Aniline-d5 是 Aniline 的氘代化合物。Aniline 的 CAS 号为 62-53-3。Aniline 通过铁过载和通过血红素加氧酶 1 上调诱导氧化应激对脾脏产生毒性。它会导致 p-IKKα 和 p-IKKβ 显着增加,进而增加 NF-κB 和 AP-1 结合活性。

同位素标记化合物

(S)-Ketoprofen-d3
Cat.No: TMIJ-0207
Synonym:
Target:
Aniline-d5
Cat.No: TMIJ-0342
Synonym:
Target:
TargetMol Loading
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