25
10
1735
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11580 |
Heme Oxygenase-1-IN-1
HO-1-IN-1 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Heme Oxygenase-1-IN-1 (HO-1-IN-1) 是一种血红素加氧酶 1 (HO-1) 抑制剂,IC50=250 nM。 | |||
T11580L |
Heme Oxygenase-1-IN-1 hydrochloride
HO-1-IN-1 hydrochloride |
Others | Others |
HO-1-IN-1 hydrochloride is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM). | |||
T13396 |
Zinc Protoporphyrin
Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX |
Apoptosis; Reactive Oxygen Species; Endogenous Metabolite | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB |
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) 是一种具有口服活性的,竞争性血红素加氧酶-1 抑制剂,显著减弱间苯三酚对 H2O2 的保护作用,具有抗癌活性。它用于评估人群铁状态与血红蛋白浓度的组合,也可用作个体孕妇和儿童缺铁的筛查标志物。 | |||
T61078 |
Heme Oxygenase-1-IN-2
|
Others | Others |
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM. | |||
T60847 |
Heme Oxygenase-2-IN-1
|
Others | Others |
Heme Oxygenase-2-IN-1 (Compound 9) 是血红素加氧酶 (HO-2) 的选择性抑制剂。Heme Oxygenase-2-IN-1 对 HO-1和HO-2 的IC50值分别为 14.9 μM 和0.9 μM。 | |||
T3459 |
VK3-OCH3
2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na |
Others | Others |
VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) 是一种通过血红素加氧酶(HO-1) 相关机制的选择性抗肿瘤剂;维生素 K3 类似物。 | |||
T4977 |
Sofalcone
索法酮,SU-88 |
Antibacterial; Autophagy | Autophagy; Microbiology/Virology |
Sofalcone (SU-88) 可诱导血红素加氧酶-1在胃肠上皮中的表达,是一种抗胃溃疡剂。 | |||
T75098 |
HIF-PHD-IN-3
|
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
HIF-PHD-IN-3 是一种有效的 hiPSC-CM 心脏保护支架,对 HIF-PHD 有潜在的抑制作用,可调节血红素加氧酶-1,可用于研究贫血。 | |||
T0839L |
S-(+)-Ketoprofen
RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen,(S)-(+)-酮洛芬,右旋酮洛芬 |
COX | Immunology/Inflammation; Neuroscience |
S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) 抑制 COX-1和 COX-2的IC50值分别为 1.9 和 27 nM。 | |||
T27064 |
CP-312
CP312,Cardioprotectant 312 |
Reactive Oxygen Species; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; NF-κB |
CP-312 (Cardioprotectant 312)是一种抗氧化防御反应激活剂,它通过诱导血红素加氧酶-1发挥作用,通过诱导 HMOX1 表达来靶向抗氧化反应网络,从而保护 hiPSC-CM 的活力。CP-312 保护人 iPSC 衍生的心肌细胞免受氧化应激。 | |||
T36113 |
Cobaltic Protoporphyrin IX chloride
Protoporphyrin IX cobaltic chloride |
Autophagy | Autophagy |
Cobaltic Protoporphyrin IX chloride (CoPP)是一种有效的血红素加氧酶 1(HO-1)诱导剂,具有抗病毒活性,通过诱导 I 型 IFN 反应来抑制甲型流感病毒(IAV)感染。 | |||
T1394 |
Ibuprofen
Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil |
COX | Immunology/Inflammation; Neuroscience |
Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID),具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂,IC50值分别为 13 和 370 μM,导致前列腺素和血栓素前体的形成减少。 | |||
T0839 |
Ketoprofen
酮基布洛芬,RP-19583,酮洛芬 |
Apoptosis; COX; MRP | Apoptosis; Immunology/Inflammation; Neuroscience |
Ketoprofen (RP-19583) 是一种非甾体抗炎剂,能够有效地抑制COX 的活性,在人血单核细胞中,对 COX-1 和 COX-2 的IC50值分别为 2 nM 和 26 nM。 | |||
T70901 |
QC-308 HCl
|
Others | Others |
QC-308 HCl is a novel Heme Oxygenase-1 Inhibitor (HO-1 IC50=0.27μM; HO-2 IC50=0.46μM). | |||
T68288 |
OB-24 free base
|
Others | Others |
OB-24 free base is a potent and selective heme oxygenase 1 (HO-1) inhibitor. | |||
T30681 |
CABP
2-CABP,2CABP,2 CABP |
Others | Others |
CABP is a transition analog of ribulos-1, 5-diphosphate carboxylase/oxygenase (Rubisco). | |||
T13524 |
9-cis-β-Carotene
|
Others | Others |
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo. | |||
T73666 |
Proglumetacin
|
Others | Others |
Proglumetacin 是一种口服有效的环加氧酶 (cyclo-oxygenase) 抑制剂。Proglumetacin 可以抑制 SARS-CoVMpro(新冠病毒的主要蛋白酶),其 AC50为 8.9 μM。Proglumetacin 具有抗炎活性,可用于炎症(如类风湿关节炎、过敏性气囊炎)的研究。 | |||
T78623 |
Cobalt protoporphyrin IX
|
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Cobalt protoporphyrin IX 作为一种特异性的血红素加氧酶-1 (HO-1) 诱导剂,表现出对甲型流感病毒 (IAV) 的广谱抗病毒活性。 | |||
T63075 |
ALOX15-IN-1
|
Others | Others |
ALOX15-IN-1 (compound 8b) 是一种选择性的、有效的兔和人 ALOX15 亚油酸加氧酶 (linoleate oxygenase) 活性抑制剂,能够作用于 ALOX15 直系同源物亚油酸 (LA) (IC50: 0.04 μM) 和花生四烯酸 (AA) (IC50: 2.06 μM)。 | |||
T41175 |
OB 24 hydrochloride
|
Others | Others |
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol. | |||
T78508 |
Delmitide acetate
RDP-58 acetate |
IFNAR | Immunology/Inflammation |
Delmitide acetate (RDP58) 是一种 d-异构体十肽,具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成,同时提高血红素加氧酶 1 的活性,可用于针对溃疡性结肠炎的研究。 | |||
T74600 |
Keap1-Nrf2-IN-9
|
Others | Others |
Keap1-Nrf2-IN-9(compound 11)是一种有效Keap1-Nrf2PPI抑制剂,IC50为0.575 µM。该化合物能够提升Nrf2靶基因表达,涉及血红素加氧酶1 (Hmox1)、谷胱甘肽S转移酶P (GstP) 以及谷氨酸-半胱氨酸连接酶的催化(Gclc)与调节(Gclm)亚基。在ARPE19细胞中,Keap1-Nrf2-IN-9展现出无细胞毒活性。 | |||
T75238 |
YS-49 monohydrate
|
Others | Others |
YS-49 (单水合物) 作为PI3K/Akt(RhoA的下游靶点)的激活剂,有效降低3-甲基胆碱处理的细胞中RhoA/PTEN的活性。此外,YS-49通过促进血红素加氧酶(HO-1)的表达,抑制血管紧张素II(Ang II)诱导的血管平滑肌细胞(VSMC)增殖。作为一种异喹啉化合物生物碱,YS-49因激活心脏β-adrenoceptors而显示出显著的正性肌力效应。 | |||
TP2109 |
TAT 14
|
Nrf2 | Immunology/Inflammation |
TAT-14 是 由14 个氨基酸组成的多肽,是 Nrf2激活因子,表现出抗炎活性。它通过靶向 Nrf2 上 Keap1 的结合位点而非 Nrf2 mRNA 表达来提高 Nrf2 蛋白水平。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3694 |
Coniferaldehyde
|
NOS; COX; Nrf2; PKC; Autophagy | Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience |
Coniferaldehyde 能显着抑制酒球菌菌株的生长活力。 Coniferaldehyde 通过诱导血红素加氧酶 1 (HO-1) 发挥抗炎特性。 | |||
T6S1302 |
Carnosol
|
Nrf2; Endogenous Metabolite; S6 Kinase | Immunology/Inflammation; MAPK; Metabolism; PI3K/Akt/mTOR signaling |
Carnosol 是 Nrf2激活剂,增加 Nrf2 的水平以及能促进血红素氧合酶 1(HMOX1) 表达。它是核糖体 S6激酶(RSK2)抑制剂,可用于胃癌相关研究,IC50值约为 5.5 μM。 | |||
T6S1027 |
Tussilagone
|
Others | Others |
Tussilagone 是Tussilago farfara 的主要活性成分,具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应,提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。 | |||
T5515 |
Hemin
氯化血红素,Hemin chloride |
Mitophagy; Ferroptosis; Autophagy | Apoptosis; Autophagy |
Hemin (Hemin chloride) 是一种含有氯的含铁卟啉,一种血红素加氧酶 (HO)-1 诱导剂。Hemin 对卟啉病具有治疗活性,可以减少患者的血红素缺乏,从而通过生物化学反馈抑制 δ-氨基乙酰丙酸合成酶的活性。 | |||
T4868 |
gamma-Linolenic acid
gamolenic acid,γ-Linolenic acid,γ-亚麻酸 |
Endogenous Metabolite | Metabolism |
gamma-Linolenic acid (gamolenic acid) 是一种 omega-6 (n-6),18 碳 (18C-) 多不饱和脂肪酸 (PUFA),可以从人乳和植物种子油中提取。 | |||
T6429 |
Caffeic Acid Phenethyl Ester
Phenylethyl Caffeate,咖啡酸苯乙酯,CAPE |
Apoptosis; NF-κB | Apoptosis; NF-κB |
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) 是咖啡酸的苯乙醇酯,是蜂巢蜂胶的生物活性成分。它抑制核转录因子 NF-kappa B 的激活,具有抗肿瘤、细胞保护和免疫调节活性。它抑制 PDGF 诱导的血管平滑肌细胞增殖。 | |||
T2915 |
Bardoxolone
RTA 401,齐墩果烷三萜化合物,CDDO |
Others; Nrf2 | Immunology/Inflammation; Others |
Bardoxolone (CDDO) 是新型核调节因子激活剂。 | |||
TN3057 |
4-O-Methylbutein
|
Autophagy | Autophagy |
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of HO-1 has proven to be a useful tool for fighting inflammation. | |||
TN4420 |
Latifolin
檀木 |
IL Receptor; IκB/IKK; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Antifection; Autophagy | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB |
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi. | |||
TN4064 |
Flavoglaucin
|
Phosphatase; IL Receptor; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Autophagy | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammato |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00817 |
HO-1 Protein, Human, Recombinant
HO,HMOX1,HO-1,Heme Oxygenase ... |
Human | E. coli |
Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy me... | |||
TMPH-01432 |
HMOX1 Protein, Human, Recombinant (His)
HMOX1,Heme oxygenase 1 |
Human | E. coli |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. HMOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHi... | |||
TMPY-02519 |
BLVRB Protein, Human, Recombinant (His)
HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U... |
Human | E. coli |
Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i... | |||
TMPY-04451 |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1) |
Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-04069 |
Neurotrophin 3 Protein, Human, Recombinant
NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3 |
Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ... | |||
TMPY-00586 |
CLEC-2 Protein, Mouse, Recombinant (hFc)
1810061I13Rik,Clec2,C-ty... |
Mouse | HEK293 Cells |
CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1. | |||
TMPY-00986 |
IL-34 Protein, Mouse, Recombinant (His)
interleukin 34,2010004A03Rik,AI593503 |
Mouse | HEK293 Cells |
IL-34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q8R1R4-1. | |||
TMPY-00991 |
LIFR Protein, Human, Recombinant (His)
STWS,CD118,SJS2,LIF-R,leukemia inhibitory ... |
Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1. | |||
TMPY-02412 |
ENO1 Protein, Human, Recombinant (His)
PPH,NNE,enolase 1, (alpha),ENO1L1... |
Human | E. coli |
ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1. | |||
TMPY-03956 |
Fas Ligand Protein, Human, Recombinant (His)
TNLG1A,FASL,FASLG,CD178,CD95-L,APT1 |
Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... | |||
TMPY-04413 |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
hIRE1p,endoplasmic reticulum to nucleus signaling <... |
Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1. | |||
TMPY-03363 |
C-Reactive Protein Protein, Human, Recombinant
C-Reactive Protein,C-reactive protein, pentraxin-related,PTX... |
Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-01349 |
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
MALA-2,Ly-47,CD54,intercellular adhesion molecule 1... |
Mouse | HEK293 Cells |
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1. | |||
TMPY-04212 |
IL-16 Protein, Mouse, Recombinant (His)
白介素,interleukin 16,mKIAA4048,白细胞介素 |
Mouse | E. coli |
IL-16 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.5 kDa and the accession number is O54824-1. | |||
TMPY-00915 |
Serpin A1 Protein, Human, Recombinant (His)
PRO2275,SerpinA1,serpin peptidase inhibitor, clade ... |
Human | HEK293 Cells |
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. | |||
TMPY-05354 |
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD28 molecule,Tp44 |
Human | HEK293 Cells |
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is P10747-1. | |||
TMPY-01139 |
PDGFRA Protein, Human, Recombinant (His)
PDGFR-2,CD140A,RHEPDGFRA,platelet-derived growth fa... |
Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1. | |||
TMPY-04956 |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1. | |||
TMPY-02617 |
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
NP Protein |
H2N2 | Baculovirus Insect Cells |
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P21433-1. | |||
TMPY-05435 |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
angiopoietin 1,AGPT,AGP1,ANG1 |
Human | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1. | |||
TMPY-01853 |
SIRP gamma Protein, Human, Recombinant (His)
bA77C3.1,signal-regulatory protein gamma,SIRP γ/SIR... |
Human | HEK293 Cells |
SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1. | |||
TMPY-06051 |
SIRP alpha Protein, Human, Recombinant (hFc)
signal-regulatory protein alpha,SIRP alpha,PTPNS1,P... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01701 |
IL-12RB1 Protein, Human, Recombinant (His)
interleukin 12 receptor, β1,IL12R... |
Human | HEK293 Cells |
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1. | |||
TMPY-04782 |
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)
LIR6,leukocyte immunoglobulin like receptor A1,LIR-... |
Human | HEK293 Cells |
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is O75019-1. | |||
TMPY-01907 |
VSIG4 Protein, Human, Recombinant (His)
Z39IG,CRIg,V-set and immunoglobulin domain containing 4 |
Human | HEK293 Cells |
VSIG4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9Y279-1. | |||
TMPY-01462 |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
interleukin 11 receptor subunit alpha,hCG_... |
Human | HEK293 Cells |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1. | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPY-01834 |
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
CD16,Fc receptor, IgG, low affinity III |
Mouse | HEK293 Cells |
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is P08508-1. | |||
TMPY-01410 |
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
CD123,interleukin 3 receptor, alpha (low affinity),... |
Human | HEK293 Cells |
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1. | |||
TMPY-03273 |
IL-18 Protein, Mouse, Recombinant
interleukin 18,白细胞介素,白介素,Il-18,Igif |
Mouse | E. coli |
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1. | |||
TMPY-01431 |
L1CAM Protein, Human, Recombinant (His)
N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu... |
Human | HEK293 Cells |
L1CAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 125 kDa and the accession number is P32004-1. | |||
TMPY-05579 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-05030 |
PCDH7 Protein, Human, Recombinant (His)
BHPCDH |
Human | Baculovirus Insect Cells |
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number... | |||
TMPY-04810 |
CD47 Protein, Mouse, Recombinant (His)
AA407862,CD47 molecule,AW108519,91 |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q61735-1. | |||
TMPY-06076 |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like... |
Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. | |||
TMPY-01298 |
CADM1 Protein, Human, Recombinant (His)
Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC- |
Human | HEK293 Cells |
CADM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9BY67-1. | |||
TMPY-02154 |
FAP Protein, Human, Recombinant (His)
fibroblast activation protein, alpha,Fibroblast Activation P... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-01912 |
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
HPT-1,cadherin 17, LI cadherin (liver-inte... |
Human | HEK293 Cells |
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1. | |||
TMPY-01608 |
Decorin Protein, Human, Recombinant (His)
PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII |
Human | HEK293 Cells |
Decorin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P07585-1. | |||
TMPY-01573 |
SIRP alpha Protein, Human, Recombinant (G75A, His)
PTPNS1,signal-regulatory protein alpha,SIRP,MYD- |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-04779 |
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member... |
Human | HEK293 Cells |
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... | |||
TMPY-01459 |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
p60,TNFR60,TNFAR,TBP1,CD120a,TNFR1 |
Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
TMPY-01055 |
IL-4R Protein, Human, Recombinant (His)
interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.18 kDa and the accession number is P24394-1. | |||
TMPY-02105 |
SCF Protein, Mouse, Recombinant (His)
Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con |
Mouse | Baculovirus Insect Cells |
SCF Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is P20826-1. | |||
TMPY-04793 |
IL-35 Protein, Human, Recombinant (Flag & His)
NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NFSK,IL- |
Human | HEK293 Cells |
IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1. | |||
TMPY-05277 |
IL-4R Protein, Human, Recombinant (hFc)
IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1. | |||
TMPY-00664 |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Angiopoietin-2,AGPT2,angiopoietin 2,ANG2 |
Human | HEK293 Cells |
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is O15123-1. | |||
TMPY-04483 |
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 recepto... |
Human | Baculovirus Insect Cells |
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0207 |
(S)-Ketoprofen-d3
|
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(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。 | |||
TMIJ-0342 |
Aniline-d5
|
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Aniline-d5 是 Aniline 的氘代化合物。Aniline 的 CAS 号为 62-53-3。Aniline 通过铁过载和通过血红素加氧酶 1 上调诱导氧化应激对脾脏产生毒性。它会导致 p-IKKα 和 p-IKKβ 显着增加,进而增加 NF-κB 和 AP-1 结合活性。 |