首页工具

登录

搜索结果

Search Results for " oxidized "

Targets Recommended: Others

77

抑制剂 & 化合物

32

天然产物

1

化合物库

22

重组蛋白

2

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L6130	萜类天然产物库		622 compounds
	622 种萜类天然产物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

萜类天然产物库

Cat.No: L6130

Compounds: 622

Cat. No.	Product Name	Target	Signaling Pathways
T22231	Adenosine Dialdehyde (ADOX) 腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde	Others	Others
	Adenosine Dialdehyde (Periodate-oxidized adenosine) 是嘌呤核苷类似物，是S-腺苷高半胱氨酸水解酶（SAHH）的有效抑制剂（Ki=3.3nM）。Adenosine Dialdehyde 在体内具有较强的抗肿瘤活性。
T36173	L-Glutathione, oxidized (sodium salt)
	Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The rat...
T78639	Oxidized ATP trisodium salt oATP trisodium salt	P2X Receptor	Membrane transporter/Ion channel; Neuroscience
	Oxidized ATP (oATP) trisodium salt 是一种P2 受体广泛抑制剂，其不可逆地阻断P2X7R活化并抑制CRP引发的NLRP3炎性体激活，常用于动脉粥样硬化研究。
T8734	Choline	Others	Others
	Choline hydroxide 是一种普遍存在的水溶性营养素，通常与 B 族维生素有关。
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
T69111	2',3'-Dialdehyde ATP	Others	Others
	2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acids.
T7871	Calcium D-saccharate tetrahydrate D-Glucaric acid calcium salt,葡萄糖二酸鈣,Calcium D-saccharate tetrahydrate,D-Saccharic acid calcium salt	Others	Others
	Calcium D-saccharate tetrahydrate (Calcium D-saccharate tetrahydrate) 是一种氧化的非环状己糖。它可以抑制癌细胞的癌变和增殖。
T2069L	TH287 hydrochloride	DNA/RNA Synthesis; MTH1	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	TH287 hydrochloride 是一种选择性MTH1抑制剂，IC50值为 0.8 nM。它可用于治疗癌症的研究。
T19210	Biotin LC hydrazide Biotinamidocaproyl hydrazide,Biotin Aminocaproyl Hydrazide,(+)-Biotinamidohexanoic Acid hydrazide,BACH	Others	Others
	Biotin LC hydrazide (BACH) 是一种长链蛋白的修饰试剂。生物素 LC 酰肼可转化高碘酸盐氧化的糖蛋白，可用于靶向糖蛋白和聚糖。
T19294	Docosahexaenoic Acid methyl ester 二十二六烯酸甲酯,Methyl docosahexaenoate,all cis-DHA methyl ester	Others	Others
	Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) 是甲基化的二十二碳六烯酸类似物，能够插入膜磷脂中而不被氧化或水解。
T29099L	VB 201 CI-201	TLR	Immunology/Inflammation
	VB 201 是一种氧化磷脂小分子，具有抗炎活性，可抑制 CD14 和 Toll 样受体 2 依赖性先天细胞活化并限制动脉粥样硬化，可用于研究动脉粥样硬化。
T83633	1-N-Methyl-4-mercaptohistidine disulfide	Others	Others
	1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂，是氧化形式的卵硫醇A，抑制光触发的CF1 ATP酶活性。
T35941	DC-Chol hydrochloride Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate	Beta Amyloid	Neuroscience
	DC-Chol hydrochloride(DC-Cholesterol hydrochloride) 在适当的实验条件下能抑制 Aβ40 纤维的形成且以剂量依赖性的方式显著抑制氧化hCT的淀粉样蛋白形成。DC-Chol hydrochloride可诱导改善和平衡的免疫力，能够促进乙型肝炎疫苗的研究。
T20094	Adrenochrome Adraxone	Antioxidant	oxidation-reduction
	Adrenochrome (Adraxone) 是一种细胞毒性分子，可用于杀死细菌。Adrenochrome 是 Epinephrine 的氧化产物。Adrenochrome 是一种可作用于大鼠心脏的冠状动脉收缩化合物，与心脏毒性有关，可用于确定超氧化物歧化酶的活性。Adrenochrome 与可用于神经系统疾病研究，是拟精神病的潜在药物。
TP2488	Palmitoyl Tripeptide-38 Acetate Palmitoyl Tripeptide-38 Acetate(1447824-23-8 Free base),醋酸棕榈酰三肽 38	Others	Others
	Palmitoyl Tripeptide-38 Acetate (Palmitoyl Tripeptide-38 Acetate (1447824-23-8 Free base)) 由三个氨基酸组成，是一种二氧化脂肽。该肽的灵感来自于胶原蛋白 VI 和层粘连蛋白中天然存在的三肽。它从内部重建需要的皮肤，抚平皱纹并舒缓皮肤，尤其是前额纹、鱼尾纹、前额纹和领口。
T77577	SLU-PP-332	Estrogen/progestogen Receptor	Endocrinology/Hormones
	SLU-PP-332 是一种泛雌激素受体相关受体 (ERR) 激动剂，其对 ERRα, ERRβ 以及 ERRγ 具有很高的亲和力，EC50 值分别为 98、230 以及 430 nM。SLUPP-332 可增强骨骼肌细胞系的线粒体功能和细胞呼吸，增加 IIa 型氧化骨骼肌纤维并增强了运动耐力。SLU-PP-332 具有研究代谢性疾病以及肌肉功能改善的潜力，可能用于改善代谢紊乱和衰老。
T68217	Diazoxon	Others	Others
	Diazoxon is the oxidized form of Diazinon -- an organophosphate insecticide. Diazoxon is shown to be a more potent acetylcholinesterase (AChE) inhibitor.
T36002	4-hydroxy Hexenal 4-HHE,4-hydroxy Hexenal	Others	Others
	4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA. [1][2]
T37875	Fenbendazole sulfone	Others	Others
	Fenbendazole sulfone is a minor metabolite of the anthelmintic fenbendazole . Fenbendazole undergoes oxidation to form oxfendazole, which is further oxidized to form fenbendazole sulfone.
T35956	PAz-PC	Others	Others
	Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. PAz-PC is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.
T33490	m-PEG12-aldehyde	Others	Others
	m-PEG12-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG s
T38312	L-Cysteine-glutathione disulfide	Others	Others
	L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity.
TNU0199	8-Hydroxyadenosine	Others	Others
	Nucleoside Derivatives - 8-Modified purine nucleosides; Drugs and Inhibitors; Anticancer antibiotics; oxidized nucleic acid adduct; precursor of phosmidosine (P-prodrug)
T35843	9(R)-HODE cholesteryl ester	Others	Others
	9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
T36066	NADP+ (sodium salt hydrate)	Others	Others
	NADP+ is the oxidized form of the electron donor nicotinamide adenine dinucleotide phosphate . It serves as a cofactor in various biological reactions. In addition, the balance between these reduced and oxidized forms plays key roles in diverse cellular functions, including cell survival, the maintenance of redox status, and intracellular signaling. For example, binding of NADP+ to β-subunits of Kv channels activates ion transport, whereas NADPH stabilizes channel inactivation. NADP+ is biosynth...
T36171	KDdiA-PC	Others	Others
	Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. KDdiA-PC is one of the most potent CD36 ligands among the oxLDL species. KDdiA-PC confers CD-36 scavenger receptor binding affinity to LDL at a frequency of only two...
T36727	9(S)-HODE	Others	Others
	9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.[1],[2] It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.[3]
T35959	PGPC 1-Palmitoyl-2-glutaryl phosphatidylcholine	Others	Others
	PGPC (1-Palmitoyl-2-glutaryl phosphatidylcholine) 是一种氧化磷脂，以浓度依赖性方式激活过氧化物酶体增殖物激活受体。
T85001	PON-PC 16:0/9:0-PC	Others	Others
	PON-PC, an oxidized phospholipid with a 9-carbon fatty acyl chain ending in an aldehyde at the sn-2 position, arises from the oxidation of palmitoyl oleoyl phosphatidylcholine (POPC) or through interaction with ozone in pulmonary surfactant. It is found in oxidized LDL. At a 40 µM concentration, PON-PC diminishes the production of TNF-α, nitric oxide (NO), and NADP+ in primary mouse alveolar macrophages and lowers the bactericidal capability of RAW 264.7 cells. Additionally, levels of PON-PC inc...
T35580	POV-PC	Others	Others
	Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC conf...
T35846	13(R)-HODE cholesteryl ester	Others	Others
	13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 13(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
T36559	(±)9-HODE	Others	Others
	(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. [1][2] Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs and HODEs. [3][4]
T36172	KOdiA-PC	Others	Others
	Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine, or KOdiA-PC, is one of the most potent CD36 ligands among the oxLDL species. KOdiA-PC confers CD36 scave...
T20014	Patent Blue V calcium salt Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051
	Acid blue is a dark bluish synthetic triphenylmethane dye. It used as a food coloring. The color of the dye is pH-dependent. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. It is usable as a
T35853	9(S)-HODE cholesteryl ester	Others	Others
	9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
T36415	N-Nitroso-N-methyl-4-Aminobutyric Acid	Others	Others
	N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces bladder transitional cell carcinomas in rats when administered in the drinking water at a concentration of 300 mg/L per day.3
T35620	Ethoxyquin Dimer	Others	Others
	Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induces microvesicular steatosis and hepatocyte necrosis, as well as increases liver levels of oxidized glutathione and total lipids in mice.2
T19264	D-Methionine sulfoxide hydrochloride D-Methionine sulfoxide hydrochloride (21056-56-4 free base)	Others	Others
	D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride. Methionine sulfoxide is the oxidation product of methionine. Methionine is a restrictive amino acid in milk or legume proteins and is easily oxidized during storag
T37301	PCTR2	Others	Others
	Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 via γ-glutamyl transpeptidase. PCTR2 is found in resolving mouse exudate and in both M1 and M2 macrophages differentiated from isolated human monocytes.
T83422	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine	Others	Others
	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine 是一种由磷酸甘油、胆碱和棕榈酸构成的甘油磷酸胆碱类化合物，通常在体内氧化应激位点累积。该化合物是 B 类清道夫受体 (CD36和SR-BI) 的有效配体，特别是氧化磷脂 oxPC(CD36)。此外，氧化磷脂 (oxPLs) 在肿瘤细胞凋亡中扮演关键角色，并且在恶性胆管狭窄疾病中可能会有所增加。
T84565	9-OxoODE 9-KODE	Others	Others
	9-OxoODE, formed through the oxidation of the allylic hydroxyl group in both 9(S)-HODE and 9(R)-HODE, is present in rabbit reticulocyte plasma and mitochondrial membranes as both 9- and 13-oxoODEs, constituting approximately 2% of the total linoleate residues. The majority of these oxidized linoleate residues are esterified to membrane lipids.
T36180	Azelaoyl PAF	Others	Others
	Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PAF. Azelaoyl PAF is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-δ12,14-prostaglandin J2, and equipotent with rosiglitazone as a ligand for this receptor.
T38099	APF
	APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxim...
T76395	(Met(O)35)-Amyloid β-Protein (1-42)
	'(Met(O)35)-Amyloid β-Protein (1-42)，Aβ42的一种氧化形态，位于Met35。该化合物可形成与Aβ40具有相似大小和分布特征的寡聚体，适用于阿尔茨海默病（AD）研究。'
T74771	Diaporthein B	Others	Others
	Diaporthein B 是氧化程度极高的 pimarane 二萜之一。Diaporthein B 表现出抗结核分枝杆菌的活性，MIC 为 3.1 μg/mL。Diaporthein B 显示对 HCT 116 和 LoVo 结肠癌细胞的 IC50为 1.5-3 μM/L。
T37302	PCTR3	Others	Others
	Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.
T38123	5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
	5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production. 1.Hempel, S.L., Buettner, G.R....
T85255	1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine,PC(16:0/20:4),PAPC	Others	Others
	1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid found in biological membranes, featuring palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively. PAPC undergoes oxidation in vivo, producing derivatives that play roles in chronic inflammation and vascular disease. Additionally, PAPC has been utilized in the investigation of oxidized phospholipid signaling mechanisms. Notably, PAPC levels are diminished in isolated human multiple myeloma ce...
T75537	N-Acetyldopamine dimer-2	Others	Others
	N-Acetyldopamine dimer-2（compound 2）是一种从蝉皮黄色粉末中分离出来的N-acetyldopamine二聚体，具有抗氧化和抗炎作用。它能抑制氧化低密度脂蛋白（LDL）的氧化、ROS的生成、NO的生成以及NF-κB的活性。
T37300	PCTR1 PCTR1	Others	Others
	Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It als...

化合物

Adenosine Dialdehyde (ADOX)

Cat.No: T22231

Synonym: 腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde

Target: Others

L-Glutathione, oxidized (sodium salt)

Cat.No: T36173

Oxidized ATP trisodium salt

Cat.No: T78639

Synonym: oATP trisodium salt

Target: P2X Receptor

Cat.No: T8734

Target: Others

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

2',3'-Dialdehyde ATP

Cat.No: T69111

Target: Others

Calcium D-saccharate tetrahydrate

Cat.No: T7871

Synonym: D-Glucaric acid calcium salt,葡萄糖二酸鈣,Calcium D-saccharate tetrahydrate,D-Saccharic acid calcium salt

Target: Others

TH287 hydrochloride

Cat.No: T2069L

Target: DNA/RNA Synthesis, MTH1

Biotin LC hydrazide

Cat.No: T19210

Synonym: Biotinamidocaproyl hydrazide,Biotin Aminocaproyl Hydrazide,(+)-Biotinamidohexanoic Acid hydrazide,BACH

Target: Others

Docosahexaenoic Acid methyl ester

Cat.No: T19294

Synonym: 二十二六烯酸甲酯,Methyl docosahexaenoate,all cis-DHA methyl ester

Target: Others

Cat.No: T29099L

Synonym: CI-201

Target: TLR

1-N-Methyl-4-mercaptohistidine disulfide

Cat.No: T83633

Target: Others

DC-Chol hydrochloride

Cat.No: T35941

Synonym: Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate

Target: Beta Amyloid

Cat.No: T20094

Synonym: Adraxone

Target: Antioxidant

Palmitoyl Tripeptide-38 Acetate

Cat.No: TP2488

Synonym: Palmitoyl Tripeptide-38 Acetate(1447824-23-8 Free base),醋酸棕榈酰三肽 38

Target: Others

Cat.No: T77577

Target: Estrogen/progestogen Receptor

Cat.No: T68217

Target: Others

4-hydroxy Hexenal

Cat.No: T36002

Synonym: 4-HHE,4-hydroxy Hexenal

Target: Others

Fenbendazole sulfone

Cat.No: T37875

Target: Others

Cat.No: T35956

Target: Others

m-PEG12-aldehyde

Cat.No: T33490

Target: Others

L-Cysteine-glutathione disulfide

Cat.No: T38312

Target: Others

8-Hydroxyadenosine

Cat.No: TNU0199

Target: Others

9(R)-HODE cholesteryl ester

Cat.No: T35843

Target: Others

NADP+ (sodium salt hydrate)

Cat.No: T36066

Target: Others

Cat.No: T36171

Target: Others

Cat.No: T36727

Target: Others

Cat.No: T35959

Synonym: 1-Palmitoyl-2-glutaryl phosphatidylcholine

Target: Others

Cat.No: T85001

Synonym: 16:0/9:0-PC

Target: Others

Cat.No: T35580

Target: Others

13(R)-HODE cholesteryl ester

Cat.No: T35846

Target: Others

Cat.No: T36559

Target: Others

Cat.No: T36172

Target: Others

Patent Blue V calcium salt

Cat.No: T20014

Synonym: Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051

9(S)-HODE cholesteryl ester

Cat.No: T35853

Target: Others

N-Nitroso-N-methyl-4-Aminobutyric Acid

Cat.No: T36415

Target: Others

Ethoxyquin Dimer

Cat.No: T35620

Target: Others

D-Methionine sulfoxide hydrochloride

Cat.No: T19264

Synonym: D-Methionine sulfoxide hydrochloride (21056-56-4 free base)

Target: Others

Cat.No: T37301

Target: Others

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine

Cat.No: T83422

Target: Others

Cat.No: T84565

Synonym: 9-KODE

Target: Others

Cat.No: T36180

Target: Others

Cat.No: T38099

(Met(O)35)-Amyloid β-Protein (1-42)

Cat.No: T76395

Cat.No: T74771

Target: Others

Cat.No: T37302

Target: Others

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

Cat.No: T38123

1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC

Cat.No: T85255

Synonym: 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine,PC(16:0/20:4),PAPC

Target: Others

N-Acetyldopamine dimer-2

Cat.No: T75537

Target: Others

Cat.No: T37300

Synonym: PCTR1

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1085L	Glutathione oxidized Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG	Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Glutathione oxidized (L(-)-Glutathione) 是氧化型谷胱甘肽，谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。
T8347	Rifamycin S	Reactive Oxygen Species; ROS; Antibacterial; Antibiotic	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Rifamycin S 是一种 DNA 依赖性 RNA 聚合酶抑制剂，是一种醌和一种针对革兰氏阳性细菌的抗生素试剂。它是涉及两个电子的可逆氧化还原系统的氧化形式。它能产生活性氧并抑制微粒体脂质过氧化，可研究肺结核和麻风病。
T2S0265	Robinin NSC 9222,刺槐素	TLR	Immunology/Inflammation
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T22218	2'-Deoxyguanosine Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine (Guanine deoxyriboside) 是一种嘌呤核苷，可被2'-dG-II家族的成员识别。2'-Deoxyguanosine 与衰老、突变和致癌有关，可被分子氧氧化。
T13581	Biotin sulfone	Endogenous Metabolite	Metabolism
	Biotin sulfone 是一个被分离的天然生物素代谢物。
T4971	5'-DEOXYADENOSINE 5′-dAdo,5-脱氧腺嘌呤核苷	Endogenous Metabolite	Metabolism
	5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷，氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。
T40834	5-Hydroxymethyl-2'-deoxycytidine 5hmdC,2'-脱氧-5-(羟甲基)胞啶	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	5-Hydroxymethyl-2'-deoxycytidine 是 DNA 中 5-methyl-2'-deoxycytidine (5-mdC) 的氧化衍生物，引起DNA损伤反应，染色体畸变，复制叉损伤和细胞活力丧失。5-Hydroxymethyl-2’-deoxycytidine 复制叉不稳定性与染色质上聚（ADP-核糖）聚合酶1（PARP1）的存在有关。
T21065	Artemisitene	Others	Others
	Artemisitene 是青蒿素的氧化形式，是一种抗疟药。青蒿素前体是青蒿素生物合成的重要基础物质，包括青蒿素 B、青蒿素、青蒿酸等。
T1390	DL-Panthenol Panthenol,DL-泛醇,DL-Pantothenyl alcohol,DL-Pantothenol
	DL-Panthenol (DL-Pantothenyl alcohol) 是一种泛酸的醇类衍生物。它广泛应用于皮肤和毛发护理研究。它具有睫毛保护作用。
T3903	Angoroside C 安格洛甙C,安格洛苷C	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Angoroside C 是一种苯丙苷，从 Radix Scrophulariae 中提取到，有益于心室重构。
T1362	Hypoxanthine 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin	Others; Endogenous Metabolite	Metabolism; Others
	Hypoxanthine (Purin-6-ol)，也被称为 purine-6-ol 或 Hyp，是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
TN1043	Keracyanin chloride Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride,花青素鼠李葡糖苷	COX	Immunology/Inflammation; Neuroscience
	Keracyanin chloride (Cyanidin 3-rutinoside chloride) 是一种花青素，能够抑制氧化的小牛胸腺 DNA 中丙二醛的形成，具有抗氧化作用。
T4917	Dehydroascorbic acid (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸	Endogenous Metabolite	Metabolism
	Dehydroascorbic acid ((L)-Dehydroascorbic acid) 是维生素 C 的氧化型，能够透过血脑屏障，对中风具有有效的脑保护作用。
TN1909	Malvidin-3-glucoside chloride 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride	Others	Others
	Malvidin-3-glucoside chloride (Oenin chloride) 是一种主要的葡萄酒花青素，能够调节大脑突触可塑性和外周炎症，促进应激反应的发生。
T22446	NADP disodium salt Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐	Others	Others
	NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子，是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子，可以被交替氧化 (NADP+) 和还原 (NADPH)。
TN1787	Isomucronulatol 7-O-glucoside Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷	Others	Others
	Isomucronulatol 7-O-beta-glucoside 具有潜在的抗炎活性，在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。
TN5171	Tricetin	Apoptosis; Others; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用（PPI）的强效竞争性抑制剂，通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路，保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1（PS-1）表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症，保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T5214	Cholesteryl linoleate CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Cholesteryl linoleate 是低密度脂蛋白和动脉粥样硬化病变中主要的胆固醇酯。它存在于 LDL 中的胆固醇酯，利用 LDL 受体相关蛋白转移到表达 15-脂氧合酶的巨噬细胞和 CHO 细胞的质膜，被氧化形成胆固醇亚油酸氢过氧化物。
T36831	9-Oxononanoic Acid 9-ONA	Phospholipase; CPT	Metabolism
	9-Oxononanoic Acid是一种氧化脂肪酸，由亚油酸自氧化形成，它能提高磷脂酶 A2（PLA2）的活性，并增加离体人体血浆中血栓素 B2 的生成。9-Oxononanoic Acid 能减少肝脏新脂肪酸的合成，并提高大鼠肝脏肉碱棕榈酰转移酶（β-氧化的标志物）的活性。
T2836	Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin	MEK; PI3K; Endogenous Metabolite	MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮，可通过抑制MEK1和PI3K 来抑制皮肤癌。
T1609	NAD+ 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH; Endogenous Metabolite	Metabolism
	NAD+ (β-Nicotinamide Adenine Dinucleotide) 是一种转递氢离子的辅酶，参与细胞中的氧化还原反应。NAD+ 参与糖酵解、柠檬酸循环、脂肪酸氧化等。NAD+ 接受来自其他分子的电子形成 NADH，然后又作为还原剂来给电子。
TN1338	7Beta-Hydroxycholesterol	LDL; Calcium Channel; MAPK	MAPK; Membrane transporter/Ion channel; Metabolism
	7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
T81044	Tanshinoic acid A
	Tanshinoic acid A为氧化型丹参酮二萜类化合物，属于11,12-seco-tanshinone衍生物。
T19880	Friedelinol Friedelan-3alpha-ol,Friedelan-3-ol,NSC 407041,epi-Friedelinol,Epifriedelanol
	Friedelinol is a pentacyclic trierpene plant as the free acid or the aglycone for many saponins. Friedelinol can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
T19320	FAPy-adenine	Others	Others
	FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases.
T19565	Streptolysin O	Others	Others
	Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state .
T82335	Ganodermacetal
	Ganodermacetal是从G. amboinense中分离的高度氧化羊毛甾烷三萜类化合物，对丰年虾幼虫表现出显著毒性。
T10928	Cytochalasin A	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhy
TN5174	Trichosanatine	MMP; LDL; p38 MAPK; Lipoxygenase; ROS	Immunology/Inflammation; MAPK; Metabolism; Proteases/Proteasome
	Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine can alleviate oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1/p38 MAPK pathway.
T82751	Celloheptaose
	Celloheptaose为含七个葡萄糖残基的低聚糖，作为多糖单加氧酶(PMOs)的底物，催化形成氧化的纤维素寡糖。
T75566	11-Oxomogroside II A1	Others	Others
	11-Oxomogroside II A1（化合物 7）是一种从罗汉果乙醇提取物中分离的氧化葫芦苷，对12-O-十四烷酰基激素-13-乙酸酯（TPA）诱导的Epstein-Barr病毒（EBV）早期抗原（EBV-EA）活化具有抑制效果，并对一氧化氮（NO）供体（+/-）-(E)-甲基-2-[(E)羟基亚氨基]-5-硝基-6-甲氧基-3-己酰胺（NOR 1）的活化也展示出轻微的抑制作用。
T83915	Norbixin hydrate	Others	Others
	Norbixin是一种在B. orellana中发现的类胡萝卜素，具有多样的生物活性。在无细胞测试中，它与过氧化物酶体增殖物激活受体γ (PPARγ)结合（Ki = 1.15 µM）。在心脑血管代谢综合征大鼠模型中，Norbixin (47.7 mg/kg) 能够减轻高血糖、高胰岛素血症和胰岛素抗性，降低血清脂质水平及心脏中硫代巴比妥酸反应性物质（TBARS）和谷胱甘肽（GSH）的水平。在胆固醇诱导的动脉粥样硬化兔模型中，它降低氧化型LDL和主动脉蛋白氧化水平，并减少动脉粥样硬化面积。Norbixin（每天0.1和1 mg/kg）减少汞诱导的大鼠肝细胞和白细胞DNA损伤。此外，它还能预防与年龄相关的黄斑变性（AMD）Abca4-/- Rdh8-/-小鼠模型中的光感受器退化。

天然产物

Glutathione oxidized

Cat.No: T1085L

Synonym: Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG

Target: Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Cat.No: T8347

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

Cat.No: T2S0265

Synonym: NSC 9222,刺槐素

Target: TLR

2'-Deoxyguanosine

Cat.No: T22218

Synonym: Deoxyguanosine,Guanine deoxyriboside

Target: Endogenous Metabolite

Cat.No: T13581

Target: Endogenous Metabolite

5'-DEOXYADENOSINE

Cat.No: T4971

Synonym: 5′-dAdo,5-脱氧腺嘌呤核苷

Target: Endogenous Metabolite

5-Hydroxymethyl-2'-deoxycytidine

Cat.No: T40834

Synonym: 5hmdC,2'-脱氧-5-(羟甲基)胞啶

Target: PARP

Cat.No: T21065

Target: Others

Cat.No: T1390

Synonym: Panthenol,DL-泛醇,DL-Pantothenyl alcohol,DL-Pantothenol

Cat.No: T3903

Synonym: 安格洛甙C,安格洛苷C

Target: Prostaglandin Receptor

Cat.No: T1362

Synonym: 次黄嘌呤,6-羟基嘌呤,6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin

Target: Others, Endogenous Metabolite

Keracyanin chloride

Cat.No: TN1043

Synonym: Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride,花青素鼠李葡糖苷

Target: COX

Dehydroascorbic acid

Cat.No: T4917

Synonym: (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸

Target: Endogenous Metabolite

Malvidin-3-glucoside chloride

Cat.No: TN1909

Synonym: 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride

Target: Others

NADP disodium salt

Cat.No: T22446

Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Target: Others

Isomucronulatol 7-O-glucoside

Cat.No: TN1787

Synonym: Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Target: Others

Cat.No: TN5171

Target: Apoptosis, Others, Nrf2

Cholesteryl linoleate

Cat.No: T5214

Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester,胆甾烯基亚油酸酯

Target: Others, Endogenous Metabolite

9-Oxononanoic Acid

Cat.No: T36831

Synonym: 9-ONA

Target: Phospholipase, CPT

Cat.No: T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Cat.No: T1609

Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

7Beta-Hydroxycholesterol

Cat.No: TN1338

Target: LDL, Calcium Channel, MAPK

Tanshinoic acid A

Cat.No: T81044

Cat.No: T19880

Synonym: Friedelan-3alpha-ol,Friedelan-3-ol,NSC 407041,epi-Friedelinol,Epifriedelanol

Cat.No: T19320

Target: Others

Cat.No: T19565

Target: Others

Cat.No: T82335

Cat.No: T10928

Target: HIV Protease

Cat.No: TN5174

Target: MMP, LDL, p38 MAPK, Lipoxygenase, ROS

Cat.No: T82751

11-Oxomogroside II A1

Cat.No: T75566

Target: Others

Norbixin hydrate

Cat.No: T83915

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03351	LOX-1 Protein, Cynomolgus, Recombinant (His) oxidized low density lipoprotein (lectin-like) rece...	Cynomolgus	HEK293 Cells
	LOX-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.9 kDa and the accession number is G7PJT2.
TMPY-04066	LOX-1 Protein, Rat, Recombinant (His) oxidized low density lipoprotein (lectin-like) rece...	Rat	HEK293 Cells
	LOX-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is O70156.
TMPY-03371	LOX-1 Protein, Rat, Recombinant (hFc) OLR1,Lox1,Oldlr1,oxidized low density lipoprotein (...	Rat	HEK293 Cells
	LOX-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.9 kDa and the accession number is O70156.
TMPH-00888	APEH Protein, Human, Recombinant (His) Acylamino-acid-releasing enzyme,Acylaminoacyl-peptidase,...	Human	E. coli
	This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. APEH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.2 kDa and the accession number is P13798.
TMPY-02490	LOX-1 Protein, Human, Recombinant (His) LOXIN,SCARE1,SLOX1,LOX1,OLR1,oxidized low density l...	Human	HEK293 Cells
	LOX-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P78380.
TMPJ-01319	TINAGL1 Protein, Human, Recombinant (His) LCN7,Tubulointerstitial nephritis antigen-like (TINAGL1),	Human	HEK293 Cells
	TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells.
TMPH-03364	RBCK1 Protein, Rat, Recombinant (His & Myc) Heme-oxidized IRP2 ubiquitin ligase 1 homolog,RING-...	Rat	E. coli
	RBCK1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 65.1 kDa and the accession number is Q62921.
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th...
TMPH-03020	MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO) mtr,Mycothione reductase,Mycothiol-disulfide reductase,NADPH...	Mycobacterium tuberculosis	E. coli
	Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.
TMPY-03605	Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His) GLRX,GRX,GRX1,glutaredoxin	Human	E. coli
	Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. Glutaredoxin-1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. Glutaredoxin-1 exists in either a reduced or an oxidized form. Glutaredoxins function as electron carriers ...
TMPJ-00463	BDH2 Protein, Human, Recombinant (His) Oxidoreductase UCPA,Dehydrogenase/Reductase SDR Family Membe...	Human	E. coli
	3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) NAD(+)--diphthamide ADP-ribosyltransferase,Exotoxin A,eta,Ps...	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38. Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 39.9 kDa and the accession number is P11439.
TMPH-03561	lsdB Protein, S. aureus, Recombinant (His & SUMO) Fur-regulated protein B,Iron-regulated surface determinant p...	Staphylococcus aureus	E. coli
	Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization. Promotes also resistance to hydrogen peroxide and killing by neutrophils. lsdB Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is ...
TMPY-00116	MTH1 Protein, Human, Recombinant (His) MTH1,nudix (nucleoside diphosphate linked moiety X)-type mot...	Human	E. coli
	NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1 protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Cancers can survive the oxidative conditions by upregulating nucleoside diphosphate lin...
TMPY-02582	Ferritin light chain Protein, Human, Recombinant (His) NBIA3,LFTD,MGC71996,ferritin, light polypeptide	Human	E. coli
	Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Storage of iron in the tissues occurs in the form of ferritin and hemosiderin. The latter originates from ferritin that has undergone intracellular digestion of its protein shell, leaving the iron core. Ferritin and hemosiderin are components of a continuum. Fer...
TMPJ-00955	MDH1 Protein, Human, Recombinant (His) Cytosolic Malate Dehydrogenase,MDH1,MDHA,Diiodophenylpyruvat...	Human	E. coli
	Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up...
TMPJ-01020	GFER Protein, Human, Recombinant (His) Augmenter of liver regeneration,FAD-linked sulfhydryl oxidas...	Human	E. coli
	GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ER...
TMPJ-00292	CD36 Protein, Human, Recombinant (hFc) FATCHDS7,Glycoprotein IIIb,SCARB3,CD36,Fatty acid translocas...	Human	HEK293 Cells
	Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition rece...
TMPJ-01459	FGF-21 Protein, Cynomolgus, Recombinant (His) Fibroblast Growth Factor 21,FGF-21,FGF21	Cynomolgus	HEK293 Cells
	Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diab...
TMPY-02798	NEIL1 Protein, Human, Recombinant (His) NEI1,nei endonuclease VIII-like 1 (E. coli),FPG1,hFPG1	Human	E. coli
	NEIL1 is a member of DNA glycosylases. DNA glycosylases are a family homologous to the bacterial Fpg/Nei family. They play a role in base excision repair which is the mechanism by which damaged bases in DNA are removed and replaced. The first step of this process is catalyzed by DNA glycosylases. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact, creating an apurinic/apyrimidinic site, commonly referred to as an AP site. NEIL1 functions in base excision r...
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His) acetyl-CoA acetyltransferase 2	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc) Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi...	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li...

重组蛋白

LOX-1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03351

Species: Cynomolgus

Expression System: HEK293 Cells

LOX-1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04066

Species: Rat

Expression System: HEK293 Cells

LOX-1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03371

Species: Rat

Expression System: HEK293 Cells

APEH Protein, Human, Recombinant (His)

Cat.No: TMPH-00888

Species: Human

Expression System: E. coli

LOX-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02490

Species: Human

Expression System: HEK293 Cells

TINAGL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01319

Species: Human

Expression System: HEK293 Cells

RBCK1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03364

Species: Rat

Expression System: E. coli

LON PROTEASE Protein, E. coli, Recombinant (His)

Cat.No: TMPY-00541

Species: E. coli

Expression System: E. coli

MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03020

Species: Mycobacterium tuberculosis

Expression System: E. coli

Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03605

Species: Human

Expression System: E. coli

BDH2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00463

Species: Human

Expression System: E. coli

Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)

Cat.No: TMPH-03168

Species: Pseudomonas aeruginosa

Expression System: E. coli

lsdB Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03561

Species: Staphylococcus aureus

Expression System: E. coli

MTH1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00116

Species: Human

Expression System: E. coli

Ferritin light chain Protein, Human, Recombinant (His)

Cat.No: TMPY-02582

Species: Human

Expression System: E. coli

MDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00955

Species: Human

Expression System: E. coli

GFER Protein, Human, Recombinant (His)

Cat.No: TMPJ-01020

Species: Human

Expression System: E. coli

CD36 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00292

Species: Human

Expression System: HEK293 Cells

FGF-21 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-01459

Species: Cynomolgus

Expression System: HEK293 Cells

NEIL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02798

Species: Human

Expression System: E. coli

ACAT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04813

Species: Rat

Expression System: E. coli

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02690

Species: Mouse

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0167	6-Hydroxypurine-d4
	6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine，也被称为 purine-6-ol 或 Hyp，属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物，是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下，Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤，黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
T71981	Gliclazide-d4
	Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...

同位素标记化合物

6-Hydroxypurine-d4

Cat.No: TMID-0167

Cat.No: T71981

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼