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Search Results for " organism "

Targets Recommended: ribosome Antibacterial Antibiotic

6

抑制剂 & 化合物

7

天然产物

10

化合物库

8

重组蛋白

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Cat. No.	Product Name
L1380	转录因子库		695 compounds
	695 种转录因子靶向、结构新颖的化合物；
L5200	抗代谢疾病化合物库		1544 compounds
	1544 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1800	抗感染化合物库		2938 compounds
	2938 种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L9820	β-内酰胺类化合物库		97 compounds
	97 种β-内酰胺类化合物的集合，可以用于高通量和高内涵筛选；
L6620	抗寄生虫天然产物库		253 compounds
	253 个抗寄生虫相关的天然产物集合，是药物开发、药理研究的有效工具；
L2570	人代谢物化合物库		4454 compounds
	4454 种人代谢物的独特集合，用于高通量、高内涵筛选；
L6610	抗感染天然产物库		1060 compounds
	1060 个抗感染相关的天然产物集合，是药物开发、药理研究的有效工具；
L6020	天然产物单体化合物库		16627 compounds
	16627 种精选天然产物集合，结构多样，遍布多种动植物与微生物；

化合物库

转录因子库

Cat.No: L1380

Compounds: 695

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1544

抗感染化合物库

Cat.No: L1800

Compounds: 2938

代谢化合物库

Cat.No: L2560

Compounds: 2320

核受体化合物库

Cat.No: L1510

Compounds: 531

β-内酰胺类化合物库

Cat.No: L9820

Compounds: 97

抗寄生虫天然产物库

Cat.No: L6620

Compounds: 253

人代谢物化合物库

Cat.No: L2570

Compounds: 4454

抗感染天然产物库

Cat.No: L6610

Compounds: 1060

天然产物单体化合物库

Cat.No: L6020

Compounds: 16627

Cat. No.	Product Name	Target	Signaling Pathways
T0788L	Spectinomycin dihydrochloride pentahydrate 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素，可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。
T79903	Sirtuin-1 inhibitor 1	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Sirtuin-1 inhibitor 1 是一种针对去乙酰化酶-1（Sirtuin-1）的抑制剂，可用于研究机体的衰老和细胞的死亡。
T19860	Clavulanic Acid BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151	Antibacterial; Antifungal	Microbiology/Virology
	Clavulanic Acid(RX-10100) 是一种由生物体克拉维链霉菌产生的主要β-内酰胺类抗生素，是一种强效的细菌 β-内酰胺酶抑制剂，用于研究细菌引起的感染。Clavulanic Acid 具有广谱的生物活性，对多种革兰氏阳性和革兰氏阴性细菌均有活性。
T69388	PD 0305970	Others	Others
	PD 0305970 is new bacterial gyrase and topoisomerase inhibitor that possess outstanding in vitro and in vivo activities against a wide spectrum of bacterial species including quinolone- and multidrug-resistant gram-positive and fastidious organism groups.
T69350	Ethionamide HCl	Others	Others
	Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and ...
T38101	Bisucaberin	Others	Others
	Bisucaberin is a siderophore and bacterial metabolite that has been found inA. haloplanktisand has anticancer activity.1,2It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 μM, respectively) and sensitizes fibrosarcoma 1023 cells to macrophage-mediated cytolysis. 1.Hou, Z., Raymond, K.N., O’Sullivan, B., et al.A preorganized siderophore: Thermodynamic and structural characterization of alcaligin and bisucaberin, microbial macrocyclic dihydroxamate chelating agentsInorg...

化合物

Spectinomycin dihydrochloride pentahydrate

Cat.No: T0788L

Synonym: 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

Sirtuin-1 inhibitor 1

Cat.No: T79903

Target: Sirtuin

Clavulanic Acid

Cat.No: T19860

Synonym: BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151

Target: Antibacterial, Antifungal

Cat.No: T69388

Target: Others

Ethionamide HCl

Cat.No: T69350

Target: Others

Cat.No: T38101

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7480	1-Undecanol 十一醇,Undecyl alcohol,1-Hendecanol	Others	Others
	1-Undecanol (1-Hendecanol) 是水果、黄油、鸡蛋和熟猪肉等许多食品中的天然产物，用作调味成分。它也可通过微生物从 2-tridecanol 中产生。
T0788	Spectinomycin dihydrochloride 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。
TN6826	D-Xylose (2S,3R,4S,5R)-oxane-2,3,4,5-tetrol
	D-Xylose ((2S,3R,4S,5R)-oxane-2,3,4,5-tetrol)是一种广泛存在于酵母菌中的单糖，参与生物体的代谢。
T1165	Ethionamide Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide	Dehydrogenase; CAT; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; oxidation-reduction
	Ethionamide (2-ethylthioisonicotinamide) 是一种抗结核抗生素。
TN5250	Vomifoliol	VEGFR; NF-κB; HIF	Angiogenesis; Chromatin/Epigenetic; NF-κB; Tyrosine Kinase/Adaptors
	Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol dehydrogenase activity. Vomifoliol and
TN3753	Dalbergioidin	Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad	Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ...
T81991	Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside
	Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside为一种从O. dentata叶中提取的酰化坎氨酚葡萄糖苷，用作污染生物（蓝贻贝M. edulis）的驱虫剂。

天然产物

Cat.No: T7480

Synonym: 十一醇,Undecyl alcohol,1-Hendecanol

Target: Others

Spectinomycin dihydrochloride

Cat.No: T0788

Synonym: 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

Cat.No: TN6826

Synonym: (2S,3R,4S,5R)-oxane-2,3,4,5-tetrol

Cat.No: T1165

Synonym: Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide

Target: Dehydrogenase, CAT, Antibacterial, Antibiotic

Cat.No: TN5250

Target: VEGFR, NF-κB, HIF

Cat.No: TN3753

Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad

Kaempferol-3-O-[2″,6″-di-O-E-p-coumaroyl]-β-D-glucopyranoside

Cat.No: T81991

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01379	SEMA4D Protein, Cynomolgus, Recombinant (His) Semaphorin-4D,FLJ33485,FLJ46484,SEMA4D,FLJ39737,coll-4,FLJ34...	Cynomolgus	HEK293 Cells
	Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 80.1 kDa and the accession number is A0A2K5TZC9.
TMPK-00404	SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated FLJ39737,CD100,SEMAJ,C9orf164,FLJ34282,M-sema-G,FLJ46484,Sem...	Human	HEK293 Cells
	Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1.
TMPK-00403	SEMA4D Protein, Human, Recombinant (His & Avi) CD100,FLJ34282,SEMA4D,Semaphorin-4D,coll-4,SEMAJ,MGC169141,C...	Human	HEK293 Cells
	Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1.
TMPH-00208	Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His) fim3,Serotype 3 fimbrial subunit	Bordetella pertussis	E. coli
	Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process. Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant ...
TMPJ-01034	TIM Protein, Human, Recombinant (His) TPI1,TPI,Triose-Phosphate Isomerase,Triosephosphate Isomeras...	Human	E. coli
	Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role...
TMPJ-00379	AOC3 Protein, Human, Recombinant (hFc) SSAO,AOC3,Membrane primary amine oxidase,Copper amine oxidas...	Human	HEK293 Cells
	Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam...
TMPH-01258	DAG1 Protein, Human, Recombinant (His & Myc) Dystrophin-associated glycoprotein 1,Dystroglycan,Dystroglyc...	Human	Baculovirus Insect Cells
	The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.; Extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells. Also acts as a receptor for laminin LAMA5.; Transmembra...
TMPY-03465	Flagellin Protein, Listeria monocytogenes, Recombinant (His) flaA	Listeria monocytogenes	E. coli
	The role of flagella and motility in the attachment of the foodborne pathogen Listeria monocytogenes to various surfaces is mixed with some systems requiring flagella for an interaction and others needing only motility for cells to get to the surface. In nature this bacterium is a saprophyte and contaminated produce is an avenue for infection. Previous studies have documented the ability of this organism to attach to and colonize plant tissue. Motility mutants were generated in three wild ...

重组蛋白

SEMA4D Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01379

Species: Cynomolgus

Expression System: HEK293 Cells

SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00404

Species: Human

Expression System: HEK293 Cells

SEMA4D Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00403

Species: Human

Expression System: HEK293 Cells

Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)

Cat.No: TMPH-00208

Species: Bordetella pertussis

Expression System: E. coli

TIM Protein, Human, Recombinant (His)

Cat.No: TMPJ-01034

Species: Human

Expression System: E. coli

AOC3 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00379

Species: Human

Expression System: HEK293 Cells

DAG1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01258

Species: Human

Expression System: Baculovirus Insect Cells

Flagellin Protein, Listeria monocytogenes, Recombinant (His)

Cat.No: TMPY-03465

Species: Listeria monocytogenes

Expression System: E. coli

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