Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T85155 |
(S)-3'-hydroxy Blebbistatin
(−)-3'-hydroxy Blebbistatin,meta-hydroxy-Blebbistatin,m-hydroxy-Blebbistatin |
Others | Others |
(S)-3'-hydroxy-Blebbistatin is a more stable and less phototoxic derivative of (–)-blebbistatin, retaining the latter's properties as a selective, cell-permeable inhibitor of non-muscle myosin II ATPases. Unlike its predecessor, (S)-3'-hydroxy-Blebbistatin exhibits reduced fluorescence, improving its utility in live cell imaging applications by diminishing degradation into cytotoxic intermediates under blue light exposure (450-490 nm). It effectively inhibits the Mg-ATPase activity and in vitro ... |