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Search Results for " megakaryocyte "

Targets Recommended: PDE

3

抑制剂 & 化合物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T0160	Anagrelide Anagrelida,Xagrid,Anagrelidum,阿那格雷	PDE	Metabolism
	Anagrelide (Xagrid) 是III 型磷酸二酯酶(PDEIII)抑制剂 (IC50=36 nM)，是咪唑喹唑啉衍生物。它能够抑制血小板生成，以及抗血栓形成作用，可用作血小板聚集抑制剂。
T2562	Eltrombopag SB-497115,SB-497115-GR,艾曲波帕	Thrombin	Proteases/Proteasome
	Eltrombopag (SB-497115-GR) 是一种具有巨核细胞生成刺激活性的口服活性血小板生成素受体激动剂，可结合并刺激血小板血小板生成素受体，用于血小板减少的某些病症研究。
T6825	Eltrombopag Olamine Promacta Olamine,Revolade,艾曲泊帕乙醇胺盐,Eltrombopag diethanolamine salt,SB497115,艾曲波帕乙醇胺盐,SB-497115GR	Thrombin	Proteases/Proteasome
	Eltrombopag Olamine (Eltrombopag diethanolamine salt) 是 Eltrombopag 的口服活性乙醇胺盐，是一种血小板生成素(TPO)受体激动剂，用于血小板减少的某些病症研究。

化合物

Cat.No: T0160

Synonym: Anagrelida,Xagrid,Anagrelidum,阿那格雷

Target: PDE

Cat.No: T2562

Synonym: SB-497115,SB-497115-GR,艾曲波帕

Target: Thrombin

Eltrombopag Olamine

Cat.No: T6825

Synonym: Promacta Olamine,Revolade,艾曲泊帕乙醇胺盐,Eltrombopag diethanolamine salt,SB497115,艾曲波帕乙醇胺盐,SB-497115GR

Target: Thrombin

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00235	TPO Protein, Human, Recombinant (His) Megakaryocyte growth and development factor,C-mpl l...	Human	HEK293 Cells
	Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi...
TMPJ-01104	MPF Protein, Human, Recombinant (hFc) SMR,CAK1,CAK1 antigen,Pre-pro-megakaryocyte-potenti...	Human	HEK293 Cells
	MPF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 KDa and the accession number is Q13421.
TMPJ-01105	MPF Protein, Human, Recombinant (His) SMR,Pre-pro-megakaryocyte-potentiating factor,mesot...	Human	HEK293 Cells
	MPF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is Q13421.
TMPH-01973	Proteoglycan 4 Protein, Human, Recombinant (His) PRG4,Megakaryocyte-stimulating factor,Superficial z...	Human	P. pastoris (Yeast)
	Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.; Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages. Proteoglycan 4 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1...
TMPH-01972	Proteoglycan 4 Protein, Human, Recombinant (His & Myc) Megakaryocyte-stimulating factor,Proteoglycan 4,Sup...	Human	Baculovirus Insect Cells
	Proteoglycan 4 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Colony-Stimulating Factor,CSF2,CSF,Sargramostim,集落刺激因子,Molgr...	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryo...
TMPJ-00080	IL-11 Protein, Human, Recombinant (P. pastoris) 白细胞介素,Oprelvekin,Adipogenesis Inhibitory Factor,白介素,IL11,AGI...	Human	P. pastoris (Yeast)
	Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its recepto...
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His) platelet endothelial aggregation receptor 1	Rat	Baculovirus Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation receptor 1 (PEAR1) triggers platelet aggregation and is expressed in platelets and endothelial cells.PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and megakaryocyte and endothelial cell proliferation. PEAR1 expressi...
TMPH-01864	PITHD1 Protein, Human, Recombinant (His & Myc) PITHD1,PITH domain-containing protein 1	Human	E. coli
	Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene. PITHD1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.6 kDa and the accession number is Q9GZP4.
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His) Glycoprotein 6,GP6,glycoprotein VI (platelet),GPVI,GPIV,MGC1...	Mouse	HEK293 Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregation and thrombin generation. GPVI is also a secondary receptor required for platelet spreading on laminin. GPVI associates with the Fc receptor gamma -chain via charged aa in the TM domains of GPVI (arginine) and the FcR gamma (aspartic acid). Collagen binding by the GPVI Ig-like...

重组蛋白

TPO Protein, Human, Recombinant (His)

Cat.No: TMPJ-00235

Species: Human

Expression System: HEK293 Cells

MPF Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01104

Species: Human

Expression System: HEK293 Cells

MPF Protein, Human, Recombinant (His)

Cat.No: TMPJ-01105

Species: Human

Expression System: HEK293 Cells

Proteoglycan 4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01973

Species: Human

Expression System: P. pastoris (Yeast)

Proteoglycan 4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01972

Species: Human

Expression System: Baculovirus Insect Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-01465

Species: Human

Expression System: E. coli

IL-11 Protein, Human, Recombinant (P. pastoris)

Cat.No: TMPJ-00080

Species: Human

Expression System: P. pastoris (Yeast)

PEAR1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-00624

Species: Rat

Expression System: Baculovirus Insect Cells

PITHD1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01864

Species: Human

Expression System: E. coli

GPVI Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00605

Species: Mouse

Expression System: HEK293 Cells

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