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Search Results for " mrna-methyltransferase "

Targets Recommended: Others Histone Methyltransferase Antibiotic Antifungal

2

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16886	Sinefungin Adenosyl-Ornithine,西奈芬净,A-9145,Antibiotic 32232RP	Others; Histone Methyltransferase; Antibiotic; Antifungal	Chromatin/Epigenetic; Microbiology/Virology; Others
	Sinefungin (Adenosyl-Ornithine) 是病毒粒子mRNA (鸟嘌呤-7-)-甲基转移酶、 mRNA (核苷-2'-)-甲基转移酶和病毒增殖的有效抑制剂。它还抑制SET7/9，通过抑制H3K4甲基化来改善肾纤维化。
T79035	PRMT5-IN-28	Histone Methyltransferase	Chromatin/Epigenetic
	PRMT5-IN-28（化合物36）是一种PRMT5抑制剂，能够调控包含基因转录、mRNA剪接、DNA修复、蛋白质定位、细胞命运和信号传导等过程的蛋白质精氨酸甲基化。PRMT5的异常活性与癌症细胞的增殖、抗凋亡、侵袭转移能力增强及免疫逃逸机制的影响相关。

化合物

Cat.No: T16886

Synonym: Adenosyl-Ornithine,西奈芬净,A-9145,Antibiotic 32232RP

Target: Others, Histone Methyltransferase, Antibiotic, Antifungal

Cat.No: T79035

Target: Histone Methyltransferase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His) mRNA-methyltransferase,mRNA (guan...	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA synthesis and a potential target for antiviral, antifungal, and antiprotozoal drug discovery.
TMPY-03046	APCDD1 Protein, Human, Recombinant (hFc) HYPT1,B7323,adenomatosis polyposis coli down-regulated 1,HTS...	Human	HEK293 Cells
	Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, respectively. Mechanistically, this was due to increased levels of methylation in the promoter region of the APCDD1 gene. Consistently, the DNA methyltransferase inhibitor 5-AZA-dC, reduced DNA methylation in the APCDD1 promoter, and restored APCDD1 expression in OS tissue and cells...

重组蛋白

TAG-72 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01308

Species: Canine

Expression System: E. coli

APCDD1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03046

Species: Human

Expression System: HEK293 Cells

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