|
TMPH-01457
|
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc)
mRNA export factor ICP27 homolog
|
HHV-6B
|
E. coli
|
|
Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs. Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P52539. |
|
TMPK-01308
|
TAG-72 Protein, Canine, Recombinant (His)
mRNA-methyltransferase,mRNA (guanine-N(7))...
|
Canine
|
E. coli
|
|
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA synthesis and a potential target for antiviral, antifungal, and antiprotozoal drug discovery. |
|
TMPH-01704
|
RAE1 Protein, Human, Recombinant (GST)
Rae1 protein homolog,mRNA-associated protein mrnp 4...
|
Human
|
E. coli
|
|
Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. RAE1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.0 kDa and the accession number is P78406. |
|
TMPY-03390
|
LSM1 Protein, Human, Recombinant (His)
LSM1 homolog, mRNA degradation associated,CASM,YJL1...
|
Human
|
E. coli
|
|
LSM1 is an Sm-like protein. Sm-like proteins can be detected in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins include the Sm sequence motif, which consists of two regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM1 has a role in replication-dependent histone mRNA degradation and binds specif... |
|
TMPH-00617
|
MazF Protein, E. coli, Recombinant (His)
mRNA interferase MazF,Toxin MazF,mazF,Endoribonucle...
|
E. coli
|
P. pastoris (Yeast)
|
|
MazF Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.6 kDa and the accession number is P0AE70. |
|
TMPH-01631
|
DCP2 Protein, Human, Recombinant (His)
m7GpppN-mRNA hydrolase,mRNA-decapping enzy...
|
Human
|
E. coli
|
|
DCP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8IU60. |
|
TMPH-03565
|
MazF Protein, S. aureus, Recombinant (His)
Toxin MazF,mRNA interferase MazF,mazF,Endoribonucle...
|
Staphylococcus aureus
|
E. coli
|
|
Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE. MazF Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession... |
|
TMPH-03582
|
MazF Protein, S. epidermidis, Recombinant (His)
Endoribonuclease MazF,mRNA interferase MazF,mazF,To...
|
Staphylococcus epidermidis
|
E. coli
|
|
Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA. Neutralized by coexpression with cognate antitoxin MazE. MazF Protein, S. epidermidis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.0 kDa and the acce... |
|
TMPJ-00345
|
IGF2BP-2 Protein, Human, Recombinant (His)
IGF-II mRNA-Binding Protein 2,IGF2 mRNA-Bi...
|
Human
|
E. coli
|
|
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replicat... |
|
TMPY-03599
|
RPRD1B Protein, Human, Recombinant (His)
C20orf77,regulation of nuclear pre-mRNA domain cont...
|
Human
|
HEK293 Cells
|
|
RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phosphorylated RNAP II at target gene promoters. RNA polymerase II C-terminal domain (CTD) phosphorylation is important for various transcription-related processes. RPRD1B is a transcriptional regulator that enhances expression of CCND1. It also enhances the transcription of a number of... |
|
TMPH-03431
|
ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)
Acetyl-CoA carboxylase,ACC,Fatty acid synthetase 3,mRNA<...
|
Saccharomyces cerevisiae
|
E. coli
|
|
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) is expressed in E. coli expression system with N-10xHis tag. The predicted m... |
|
TMPH-03432
|
ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)
mRNA transport-defective protein 7,Acetyl-CoA carbo...
|
Saccharomyces cerevisiae
|
E. coli
|
|
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole. ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mol... |
|
TMPY-01762
|
IGF2BP-2 Protein, Human, Recombinant (His & GST)
insulin-like growth factor 2 mRNA binding protein 2...
|
Human
|
Baculovirus Insect Cells
|
|
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa c... |
|
TMPH-03712
|
Clp1 Protein, Xenopus laevis, Recombinant (His)
clp1,Pre-mRNA cleavage complex II protein Clp1,Poly...
|
Xenopus laevis
|
E. coli
|
|
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the... |
|
TMPJ-00507
|
EIF4E Protein, Human, Recombinant
eIF-4F 25 kDa subunit,EIF4F,eIF-4E,Eukaryotic translation in...
|
Human
|
E. coli
|
|
Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facil... |
|
TMPH-00303
|
SF3B3 Protein, Bovine, Recombinant (His)
Spliceosome-associated protein 130,Splicing factor 3B subuni...
|
Bovine
|
E. coli
|
|
SF3B3 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.6 kDa and the accession number is A0JN52. |
|
TMPH-02086
|
SRSF3 Protein, Human, Recombinant (GB1 & His)
Serine/arginine-rich splicing factor 3,Pre-mRNA-spl...
|
Human
|
E. coli
|
|
SRSF3 Protein, Human, Recombinant (GB1 & His) is expressed in E. coli. |
|
TMPJ-00705
|
BCAS2 Protein, Human, Recombinant (His, T7)
BCAS2,DNA Amplified in Mammary Carcinoma 1 Protein,Pre-m...
|
Human
|
E. coli
|
|
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator ... |
|
TMPH-02085
|
SRSF1 Protein, Human, Recombinant (His & SUMO)
Alternative-splicing factor 1,Splicing factor, arginine/seri...
|
Human
|
E. coli
|
|
SRSF1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
|
TMPH-00920
|
FTO Protein, Human, Recombinant (His & Myc)
U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylas...
|
Human
|
E. coli
|
|
FTO Protein, Human, Recombinant (His & Myc) is expressed in E. coli. |
|
TMPJ-00712
|
MPZL1 Protein, Human, Recombinant (His)
FLJ96614,mRNA,Myelin protein zero-like 1,cDNA FLJ78...
|
Human
|
HEK293 Cells
|
|
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin... |
|
TMPJ-00651
|
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Poliovirus Receptor,PVS,Nectin-Like Protein 5,NECL-5,CD155,P...
|
Human
|
HEK293 Cells
|
|
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be... |
|
TMPJ-00154
|
IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)
sIL-15 receptor subunit α,Il15ra,Interleukin-15 receptor sub...
|
Mouse
|
HEK293 Cells
|
|
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il... |
|
TMPY-04483
|
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...
|
Human
|
Baculovirus Insect Cells
|
|
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... |
|
TMPH-01282
|
ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO)
PNEM,ELAVL4,HuD,Hu-antigen D,ELAV-like protein 4
|
Human
|
E. coli
|
|
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (UTR) of target mRNAs, including GAP43, VEGF, FOS, CDKN1A and ACHE mRNA. Many of the target mRNAs are coding for RNA-binding proteins, transcription factors and proteins involved in RNA processing and/or neuronal development and function. By binding to th... |
|
TMPH-01313
|
EIF4G1 Protein, Human, Recombinant (His)
EIF4G,eIF-4-gamma 1,Eukaryotic translation initiation factor...
|
Human
|
P. pastoris (Yeast)
|
|
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation. EIF4G1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 41.6 kDa and the accession number is Q04637. |
|
TMPH-00102
|
RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc)
RBP47A,RNA-binding protein 47A,Polyadenylate-binding protein...
|
Arabidopsis thaliana
|
E. coli
|
|
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation. RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.5 kDa and the accession number is F4I3B3. |
|
TMPH-01312
|
EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)
eIF-4G 1,EIF4G,Eukaryotic translation initiation factor 4 ga...
|
Human
|
E. coli
|
|
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F complex, required for endoplasmic reticulum stress-induced ATF4 mRNA translation. EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) is expressed in E. coli expression system with N-10xHis-B2M-JD and C-Myc tag. The predicted molecular weight is 46.6 kDa and the accession nu... |
|
TMPH-02883
|
RBFOX3 Protein, Mouse, Recombinant (His & Myc)
Neuronal nuclei antigen,Rbfox3,RNA binding protein fox-1 hom...
|
Mouse
|
E. coli
|
|
Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
|
TMPH-00744
|
CsrA Protein, E. coli, Recombinant
Carbon storage regulator,csrA,Translational regulator CsrA
|
E. coli
|
E. coli
|
|
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its f... |
|
TMPH-02229
|
TRA2B Protein, Human, Recombinant (His & SUMO)
TRA2B,Transformer-2 protein homolog B,Splicing factor, argin...
|
Human
|
E. coli
|
|
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. TRA2B Protein, Human, Recombinant (His & SUMO) is expr... |
|
TMPH-02228
|
TRA2B Protein, Human, Recombinant (His & Myc)
TRA2B,Transformer-2 protein homolog B,Splicing factor, argin...
|
Human
|
Baculovirus Insect Cells
|
|
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA. |
|
TMPH-02133
|
DDX39B Protein, Human, Recombinant (GST)
UAP56,HLA-B-associated transcript 1 protein,DDX39B,ATP-depen...
|
Human
|
E. coli
|
|
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun... |
|
TMPH-01281
|
ELAVL3 Protein, Human, Recombinant (His)
PLE21,Hu-antigen C,ELAVL3,ELAV-like protein 3,HUC
|
Human
|
P. pastoris (Yeast)
|
|
RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Plays a role in the stabilization of GAP43 mRNA and in spatial learning. |
|
TMPH-01584
|
KRT7 Protein, Human, Recombinant (His & SUMO)
KRT7,Keratin, type II cytoskeletal 7,Sarcolectin,Keratin-7,T...
|
Human
|
E. coli
|
|
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
|
TMPY-03748
|
BCL2L12 Protein, Human, Recombinant (GST)
BCL2-like 12 (proline rich)
|
Human
|
E. coli
|
|
BCL2-like 12 (BCL2L12 ) is a new member of the apoptosis-related BCL2 gene family, members of which are implicated in various malignancies. The mRNA expression of BCL2L12 may constitute a novel biomarker for the prediction of short-term relapse in nasopharyngeal carcinoma. BCL2L12 is a recently identified gene belonging to the BCL2 family, members of which are implicated in hematologic malignancies, including chronic lymphocytic leukemia (CLL). BCL2L12 can be considered as a new independent prog... |
|
TMPY-03344
|
LSM3 Protein, Human, Recombinant (His)
SMX4,YLR438C,USS2,LSM3 homolog, U6 small nuclear RNA associa...
|
Human
|
E. coli
|
|
LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre-catalytic spliceosome (spliceosome B complex). Sm-like proteins can be detected in a variety of organisms. They all have the Sm sequence motif, which consists of 2 regions separated by a linker ... |
|
TMPH-00673
|
NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)
NAD-capped RNA hydrolase NudC,nudC,NADH pyrophosphatase
|
E. coli
|
E. coli
|
|
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina... |
|
TMPJ-00676
|
PPIH Protein, Human, Recombinant (His)
Peptidyl-Prolyl Cis-Trans Isomerase H,Rotamase H,PPIase H,Sm...
|
Human
|
E. coli
|
|
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the i... |
|
TMPH-00562
|
30S ribosomal protein S7 Protein, E. coli, Recombinant (His)
30S ribosomal protein S7,rpsG,Small ribosomal subunit protei...
|
E. coli
|
E. coli
|
|
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Has been shown to contact tRNA in both the P and E sites; it probably blocks exit of the E site tRNA.; Protein S7 is also a translational repressor protein; it regulates the expression of the str operon members to different degrees by binding to its mRNA... |
|
TMPH-01462
|
HNRNPH1 Protein, Human, Recombinant (GST)
HNRNPH1,Heterogeneous nuclear ribonucleoprotein H
|
Human
|
E. coli
|
|
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). HNRNPH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system... |
|
TMPH-03444
|
GCY1 Protein, S. cerevisiae, Recombinant (His)
GCY1,Galactose-inducible crystallin-like protein 1,Glycerol ...
|
Saccharomyces cerevisiae
|
P. pastoris (Yeast)
|
|
Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity. GCY1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is P14065. |
|
TMPH-02317
|
YTHDF1 Protein, Human, Recombinant (His)
YTHDF1,Dermatomyositis associated with cancer putative autoa...
|
Human
|
P. pastoris (Yeast)
|
|
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability by promoting degradation of m6A-containing mRNAs via interaction with the CCR4-NOT complex. The YTHDF paralogs (YTHDF1, YTHDF2 and YTHDF3) shares m6A-containing mRNAs targets and act redundantly to mediate mRNA degradatio... |
|
TMPJ-01297
|
WIBG Protein, Human, Recombinant (His)
Protein Wibg Homolog,Partner of Y14 and Mago,WIBG,PYM
|
Human
|
E. coli
|
|
Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partn... |
|
TMPY-00471
|
INSL4 Protein, Human, Recombinant (His)
EPIL,insulin-like 4 (placenta),PLACENTIN
|
Human
|
HEK293 Cells
|
|
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblas... |
|
TMPJ-01007
|
HRSP12 Protein, Human, Recombinant (His)
p14.5,UK114 Antigen Homolog,Heat-Responsive Protein 12,Ribon...
|
Human
|
E. coli
|
|
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels ... |
|
TMPH-02312
|
Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
WT1,WT33,Wilms tumor protein
|
Human
|
E. coli
|
|
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may b... |
|
TMPY-01557
|
MAGOH Protein, Human, Recombinant (His)
MAGOHA,MAGOH1,mago-nashi homolog, proliferation-associated (...
|
Human
|
E. coli
|
|
MAGOH (Mago Homolog, Exon Junction Complex Subunit) is a Protein Coding gene. MAGOH is the human homolog of Drosophila mago nashi, a protein that is required for normal germplasm development in the Drosophila embryo. In mammals, mRNA expression is not limited to the germplasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. The exon junction complex (EJCs) are deposited on messenger RNAs (mRNAs) during splicing and their core consi... |
|
TMPH-03615
|
Ribonuclease J Protein, Synechocystis sp., Recombinant (His & SUMO)
rnj,Ribonuclease J
|
Synechocystis
|
E. coli
|
|
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. Ribonuclease J Protein, Synechocystis sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 86.4 kDa and the accession number is P54123. |
|
TMPH-01224
|
Dihydrofolate reductase Protein, Human, Recombinant (His)
DHFR,Dihydrofolate reductase
|
Human
|
E. coli
|
|
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2. |
沪公网安备 31010602006700号