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Search Results for " lipid "
Targets Recommended: Lipid Others

604

抑制剂 & 化合物

143

天然产物

9

化合物库

115

重组蛋白

12

同位素标记化合物

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Cat. No. Product Name
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;
L7000 活性脂质化合物库

385 compounds
385 种生物活性小分子化合物,用于高通量、高内涵筛选;
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;
L8700 铁死亡化合物库

779 compounds
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L1510 核受体化合物库

531 compounds
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2501 人内源代谢化合物库 Plus

1283 compounds
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;
L9420 外泌体相关化合物库

76 compounds
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选;

化合物库

脂代谢化合物库
Cat.No: L2510
Compounds: 492
活性脂质化合物库
Cat.No: L7000
Compounds: 385
AMPK靶向分子库
Cat.No: L1120
Compounds: 80
铁死亡化合物库
Cat.No: L8700
Compounds: 779
核受体化合物库
Cat.No: L1510
Compounds: 531
抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
人内源代谢化合物库 Plus
Cat.No: L2501
Compounds: 1283
内质网应激化合物库
Cat.No: L9700
Compounds: 193
外泌体相关化合物库
Cat.No: L9420
Compounds: 76
Cat. No. Product Name Target Signaling Pathways
T38636 Monophosphoryl lipid A

Glucopyranosyl lipid A

Others Others
Monophosphoryl lipid A (MPLA), also known as Glucopyranosyl lipid A, is an agonist of toll-like receptor 4. Derived from the cell wall of nonpathogenic Salmonella, MPLA is a valuable compound for research on immunization and vaccine development.
T31963 Glyco-lipid

Glycolipid,Glyco lipid

Others Others
Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues.
T39502 Lipid 5

Others Others
Lipid 5 is an amino lipid compound that demonstrates proficient mRNA delivery in rodent and primate models, displaying favorable pharmacokinetics and minimal toxicity.
T36957 BODIPY 493/503

BDP 493/503 lipid stain,Pyrromethene 546

Others Others
BODIPY 493/503 (Pyrromethene 546) 属于亲脂性荧光染料,Ex/Em 为 493/503 nm。 BODIPY 493/503 定位于极性脂质,可用于标记细胞中性脂质含量以及活细胞和固定细胞应用。
T32779 Lipid Y

Others Others
Lipid Y is a monosaccharide precursor of E coli lipid A.
T32778 Lipid X

Others Others
Lipid X is a monosaccharide precursor of E coli lipid A.This compound is unstable in powder form and other related salt forms are recommended.
T10166 Lipid peroxidation inhibitor 1

Others Others
Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).
T32777 Lipid II binder 5107930

Compound 5107930

Others Others
Lipid II binder 5107930 is a lipid II binder which causes specific upregulation of the vancomycin-resistance associated gene vraX, which is implicated in the cell wall stress stimulon that confers glycopeptide resistance.
T74721 Lipid 29

Others Others
Lipid 29 是一种可电离的氨基脂质。Lipid 29 可用于形成脂质纳米颗粒。
T73990 Lipid M

Others Others
Lipid M (pKa: 6.75) 可用于递送 mRNA 疫苗,引发强大的免疫反应并提高耐受性。
T84679 Lipid AX4

Others Others
Lipid AX4,一种阳离子可电离脂质,具有6.89的pKa,适于形成脂质纳米颗粒(LNPs),用于mRNA的体内递送。
T84768 Lipid 10

​EA-PIP

Others Others
Lipid 10,一种具有可电离性的氨基脂质,适用于脂质纳米颗粒的合成。
T75138 Lipid 14

Others Others
Lipid 14 是一种可电离的氨基脂质,可用于合成脂质纳米粒 (LNPs)。
T74780 Lipid C24

Others Others
Lipid C24,一种阳离子可电离脂质,适用于脂质纳米颗粒(LNP)合成,主要应用于核酸递送研究。
T84769 Lipid 8

Others Others
Lipid 8为一种可电离氨基脂质,适用于脂质纳米颗粒的合成。
T84788 Lipid 15

Others Others
Lipid 15为一种具可电离性的氨基脂质,适用于脂质纳米颗粒的合成。
T84707 Ionizable lipid-2

Others Others
Ionizable lipid-2 (compound 1) 为一种可电离脂质,专用于核酸递送与脂质纳米颗粒(LNP)的构建。
T84813 Ionizable lipid-1

Others Others
Ionizable lipid-1 (化合物 II-10)为一种pKa值为6.16的可电离脂质,主要用于制备具有双层结构的脂质纳米颗粒(LNP)。
T75108 LNP Lipid-1

Others Others
LNP Lipid-1 (Method B) 为一种脂质化合物,用于脂质纳米颗粒组合物的合成中。该化合物可作为小分子活性分子、蛋白质及核酸等生物活性物质的运输载体,具有潜在应用价值。
T74971 Diamino lipid DAL4

Others Others
Diamino lipid DAL4 是一种新型脂质纳米颗粒 (LNPs),可包裹编码 IL-12、IL-27 和 GM-CSF 等细胞因子的 mRNA。Diamino lipid DAL4 能够传递细胞因子 mRNA 给肿瘤细胞,发挥抗肿瘤效力。
T75111 LNP Lipid-4

Others Others
LNP Lipid-4 (Compound 8-8)为一种脂质化合物,用于脂质纳米颗粒组合物的合成,具有在生物活性物质运输方面的潜在应用。
T84792 LNP Lipid-7

Others Others
LNP Lipid-7(Compound 7013)为一种脂质,其与LNP Lipid-6共同用于制备药物输送用的脂质纳米颗粒(LNP)。
T84801 LNP Lipid-8

Others Others
LNP Lipid-8 (11-A-M)为一种可电离脂质,无需靶向配体即可通过脂质纳米颗粒(LNP)将siRNA递送至T细胞。在小鼠模型中,装载siGFP的LNP Lipid-8能显著导致GFP基因沉默。
T83657 CCD Lipid01

LP-01

Others Others
CCD Lipid01 (LP-01) 是一种脂质膜,可用于输送生物活性制剂 。
T64006 Lipid-lowering agent-1

Others Others
Lipid-lowering agent-1 是有效的降脂剂,能够明显抑制低密度脂蛋白胆固醇 (LDLC) 和促进高密度脂蛋白胆固醇 (HDLC) 产生的药理作用。Lipid-lowering agent-1 能够明显降低高脂饮食大鼠的脂肪。
T14667 BLT-1

Others; HCV Protease Microbiology/Virology; Others; Proteases/Proteasome
BLT-1 是一种氨基硫脲铜螯合剂,是一种选择性清除受体 B1 型 (SR-BI) 抑制剂,抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T84759 mRNA-Encapsulating Lipid Excipient 1

ATX-100,ATX 100,ATX100

Others Others
mRNA-Encapsulating Lipid Excipient 1 (Compound 2) 是一种可电离脂质,基于硫代氨基甲酸盐。它用作mRNA-包封脂质纳米颗粒的赋形剂。
T33756 NSC-624871

CP 48,NSC 624871,CP48,Amido-phosphoether lipid,CP-48,NSC624871

Others Others
NSC-624871 is a potential bioactive agent. No further details yet.
TD0093 Oil Red O

Others Others
Oil Red O 用于制备染色溶液,可用于检测组织学冷冻切片中的脂质。
T9520 ALC-0159

Others Others
ALC-0159 是聚乙二醇的脂质结合物,是一种疫苗赋形剂。
T31976 Glymidine sodium

Others Others
Glymidine sodium 是口服有活性的抗糖尿病药物,也是肝脂肪分解的抑制剂。它通过抑制葡萄糖的形成,也对由于内源性脂质动员抑制而导致的丙酮酸氧化升高具有抑制作用。
T9410 SM-102

Others Others
SM-102是一种可电离的氨基脂质,用于合成脂质纳米粒子(LNPs)[1]。它在开发用于运输mRNA-based vaccines的LNPs方面展现出潜力[2]。
T4039 BIBB 515

Others Others
BIBB 515 是口服具有活力的 2,3-氧化角鲨烯环化酶选择性抑制剂,在大鼠和小鼠中的 ED50值分别为 0.2-0.5 mg/kg 和 0.36-33.3 mg/kg (1-5 小时)。它主要利用抑制低密度脂蛋白的产生,从而发挥降脂作用。
T7092 NADPH tetrasodium salt

Others; Ferroptosis; Endogenous Metabolite Apoptosis; Metabolism; Others
NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式,在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。
T7955 EB-3D

Apoptosis; AMPK; AChR Apoptosis; Chromatin/Epigenetic; Neuroscience; PI3K/Akt/mTOR signaling
EB-3D 是一种选择性胆碱激酶 α 抑制剂,对 ChoKα1 的IC50值为 1 μM。它影响 ChoKα 表达、AMPK 激活、细胞凋亡、内质网应激和脂质代谢,具有抗癌活性。
T9766 GW590735

PPAR DNA Damage/DNA Repair; Metabolism
GW590735 是一种有效的选择性 PPARα 激动剂,对 PPARα 的 EC50 为 4 nM,比 PPARδ 和 PPARγ 的选择性至少高 500 倍。 GW590735 可用于血脂异常研究。
T8461 SKI V

Apoptosis; PI3K; S1P Receptor Apoptosis; GPCR/G Protein; PI3K/Akt/mTOR signaling
SKI V 是一种非竞争性非脂质鞘氨醇激酶抑制剂,对 GST-hSK 的IC50为 2 μM。 它减少有丝分裂的第二信使鞘氨醇-1-磷酸的形成,可诱导细胞凋亡并具有抗肿瘤活性。它还抑制PI3K,对 hPI3k 的IC50为 6 μM。
TQ0105 CAY10650

Phospholipase Metabolism
CAY10650 是高效的胞浆磷脂酶A2α抑制剂,IC50=12 nM,能够抑制脂滴形成和 PGE2 分泌。
T10900 CUDA

PPAR; Epoxide Hydrolase DNA Damage/DNA Repair; Metabolism
CUDA 是一种可溶性环氧水解酶抑制剂,对小鼠 sEH 和人 sEH 作用的 IC50分别为 11.1 和 112 nM。它能选择性地上调过氧化物酶体增殖激活受体 PPARα的活性,有用于心血管疾病的研究潜力。
T7656 Apelin-13

Apelin-13 是存在于中枢和外周神经系统由13个氨基酸组成的多肽序列,是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体,对 APJ 的 EC50 值为 0.37 nM。Apelin-13 具有扩张血管和降压活性,可用于研究 2 型糖尿病综合征。
T10760 Ceramides Mixture

神经酰胺混合物,神经酰胺

Telomerase DNA Damage/DNA Repair
Ceramides Mixture 是表皮渗透屏障的主要脂质成分,参与生长抑制,细胞周期停滞和端粒酶活性的调节。它是一种内源性神经酰胺,由含羟基和非羟基脂肪酸的神经酰胺组成。
T3978 Linerixibat

GSK2330672,Iinerixibat

HBV Microbiology/Virology
Linerixibat (GSK2330672) 是高效的、不可吸收的、具有口服活性的顶端钠依赖性胆汁酸转运蛋白 (ASBT) 抑制剂,对人ASBT 的IC50为 42 nM。它是一种降脂剂,具有用于 2 型糖尿病和原发性胆源性胆管炎的研究潜力。
TP1263 Fz7-21

(Ac)-LPSDDLEFWCHVMY-NH2

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) 是一种 Frizzled 7 (FZD 7) 受体的肽抑制剂,能够选择性的与FZD7 CRD 亚类结合。它还阻断了WNT3A 介导的β-catenin 在小鼠L 细胞中的稳定作用。它对外源性WNT3A 刺激和转染WNT3A 或WNT1的HEK293细胞Wnt/β-catenin 信号传导有损伤。
T7133 Anagliptin

SK-0403,阿拉格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Anagliptin (SK-0403) 是一种选择性的二肽酰肽酶 4 抑制剂,IC50=3.8 nM,对 DPP-8/9 的选择性相对较弱,IC50分别为 68 和 60 nM。
T19033 Nile Red

Phenoxazone 9,尼罗红,Nile Blue A oxazone

Others Others
Nile Red (Nile Blue A oxazone) 是一种选择性疏水性荧光染料,针对细胞内脂质小滴和中性脂质。它在所有有机溶剂中均具有强烈的荧光性,其荧光颜色范围从金黄色到深红色。
TQ0095 Brincidofovir

CMX001,HDP-CDV

Others; Antiviral; HSV Immunology/Inflammation; Microbiology/Virology; Others
Brincidofovir (HDP-CDV) 是 Cidofovir 的一种具有口服活性的亲脂性形式的前体药物,是一种口服长效的抗病毒药物,有广泛的抗 DNA 病毒活性。
T3124 Carbendazim

Bavistin,Carbendazole,多菌灵,Mercarzole

Antifungal Microbiology/Virology
Carbendazim (Mercarzole) 是一种具有抗肿瘤活性的苯并咪唑衍生物,可用于癌症研究。它是一种口服广谱苯并咪唑杀菌剂,可作为真菌疾病研究的杀虫剂。
T11086 DOTAP chloride

(2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride

Others Others
DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) 是高效的阳离子脂质,可以在不使用辅助脂质的情况下,作用于瞬时或者稳定转染 DNA (质粒、bacmids) 和修饰核酸 (反义寡核苷酸)。
T70267 ADL 08-0011 HCl

Others Others
ADL 08-0011 is an active metabolite of the μ-opioid receptor antagonist alvimopan. It is produced from alvimopan via amide hydrolysis by gut microbiota. ADL 08-0011 is a μ-opioid receptor antagonist (Ki = 0.25 nM). It is selective for μ-opioid receptors over κ- and δ-opioid receptors (Kis = 15.8 and 31.6 nM, respectively). ADL 08-0011 inhibits endomorphin 1-induced inhibition of electrically induced contraction of isolated guinea pig ileum (pA2 = 9.4). In vivo, ADL 08-0011 (0.03-1 mg/kg) reverse...
T35343 MTI-31

MTI-31,LXI-15029

mTOR PI3K/Akt/mTOR signaling
MTI-31 (LXI-15029) 是口服有效的,高度选择性的mTORC1和mTORC2抑制剂,对 mTOR 的Kd 为 0.20 nM,IC50为 39 nM。MTI-31可用于乳腺癌的研究。

化合物

Monophosphoryl lipid A
Cat.No: T38636
Synonym: Glucopyranosyl lipid A
Target: Others
Glyco-lipid
Cat.No: T31963
Synonym: Glycolipid,Glyco lipid
Target: Others
Lipid 5
Cat.No: T39502
Synonym:
Target: Others
BODIPY 493/503
Cat.No: T36957
Synonym: BDP 493/503 lipid stain,Pyrromethene 546
Target: Others
Lipid Y
Cat.No: T32779
Synonym:
Target: Others
Lipid X
Cat.No: T32778
Synonym:
Target: Others
Lipid peroxidation inhibitor 1
Cat.No: T10166
Synonym:
Target: Others
Lipid II binder 5107930
Cat.No: T32777
Synonym: Compound 5107930
Target: Others
Lipid 29
Cat.No: T74721
Synonym:
Target: Others
Lipid M
Cat.No: T73990
Synonym:
Target: Others
Lipid AX4
Cat.No: T84679
Synonym:
Target: Others
Lipid 10
Cat.No: T84768
Synonym: ​EA-PIP
Target: Others
Lipid 14
Cat.No: T75138
Synonym:
Target: Others
Lipid C24
Cat.No: T74780
Synonym:
Target: Others
Lipid 8
Cat.No: T84769
Synonym:
Target: Others
Lipid 15
Cat.No: T84788
Synonym:
Target: Others
Ionizable lipid-2
Cat.No: T84707
Synonym:
Target: Others
Ionizable lipid-1
Cat.No: T84813
Synonym:
Target: Others
LNP Lipid-1
Cat.No: T75108
Synonym:
Target: Others
Diamino lipid DAL4
Cat.No: T74971
Synonym:
Target: Others
LNP Lipid-4
Cat.No: T75111
Synonym:
Target: Others
LNP Lipid-7
Cat.No: T84792
Synonym:
Target: Others
LNP Lipid-8
Cat.No: T84801
Synonym:
Target: Others
CCD Lipid01
Cat.No: T83657
Synonym: LP-01
Target: Others
Lipid-lowering agent-1
Cat.No: T64006
Synonym:
Target: Others
BLT-1
Cat.No: T14667
Synonym:
Target: Others, HCV Protease
mRNA-Encapsulating Lipid Excipient 1
Cat.No: T84759
Synonym: ATX-100,ATX 100,ATX100
Target: Others
NSC-624871
Cat.No: T33756
Synonym: CP 48,NSC 624871,CP48,Amido-phosphoether lipid,CP-48,NSC624871
Target: Others
Oil Red O
Cat.No: TD0093
Synonym:
Target: Others
ALC-0159
Cat.No: T9520
Synonym:
Target: Others
Glymidine sodium
Cat.No: T31976
Synonym:
Target: Others
SM-102
Cat.No: T9410
Synonym:
Target: Others
BIBB 515
Cat.No: T4039
Synonym:
Target: Others
NADPH tetrasodium salt
Cat.No: T7092
Synonym:
Target: Others, Ferroptosis, Endogenous Metabolite
EB-3D
Cat.No: T7955
Synonym:
Target: Apoptosis, AMPK, AChR
GW590735
Cat.No: T9766
Synonym:
Target: PPAR
SKI V
Cat.No: T8461
Synonym:
Target: Apoptosis, PI3K, S1P Receptor
CAY10650
Cat.No: TQ0105
Synonym:
Target: Phospholipase
CUDA
Cat.No: T10900
Synonym:
Target: PPAR, Epoxide Hydrolase
Apelin-13
Cat.No: T7656
Synonym:
Target:
Ceramides Mixture
Cat.No: T10760
Synonym: 神经酰胺混合物,神经酰胺
Target: Telomerase
Linerixibat
Cat.No: T3978
Synonym: GSK2330672,Iinerixibat
Target: HBV
Fz7-21
Cat.No: TP1263
Synonym: (Ac)-LPSDDLEFWCHVMY-NH2
Target: Wnt/beta-catenin
Anagliptin
Cat.No: T7133
Synonym: SK-0403,阿拉格列汀
Target: Proteasome, DPP-4
Nile Red
Cat.No: T19033
Synonym: Phenoxazone 9,尼罗红,Nile Blue A oxazone
Target: Others
Brincidofovir
Cat.No: TQ0095
Synonym: CMX001,HDP-CDV
Target: Others, Antiviral, HSV
Carbendazim
Cat.No: T3124
Synonym: Bavistin,Carbendazole,多菌灵,Mercarzole
Target: Antifungal
DOTAP chloride
Cat.No: T11086
Synonym: (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride
Target: Others
ADL 08-0011 HCl
Cat.No: T70267
Synonym:
Target: Others
MTI-31
Cat.No: T35343
Synonym: MTI-31,LXI-15029
Target: mTOR
Cat. No. Product Name Target Signaling Pathways
T38635 Kdo2-Lipid A ammonium

TNF; TLR; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation
Kdo2-Lipid A ammonium (KLA) 是一种具有选择性和有效性的 TLR4 激动剂,属于一种脂多糖。Kdo2-Lipid A ammonium 促使 TNF 和 PGE2 的释放。
T2824 Pedunculoside

Others; Fatty Acid Synthase Metabolism; Others
Pedunculoside 是从 Ilex rotunda Thunb 中提取的,通过对脂质形成和脂肪酸 β-氧化的调节而发挥降脂作用。
TN6772 Malabaricone C

Others Others
Malabaricone C 是天然的鞘磷脂合成酶抑制剂,对 SMS 1 和 SMS 2 的IC50分别为 3 和 1.5 μM。
T7992 4-Hydroxyflavanone

NO Synthase Immunology/Inflammation
4-Hydroxyflavanone 是一种黄酮的合成类似物,是 SREBP 成熟和脂质合成的抑制剂。它具有研究肝脏脂肪变性及血脂异常的潜力。
T19161 7α-Hydroxycholesterol

Others Others
7α-Hydroxycholesterol 是一种由酶促氧化和非酶促氧化形成的胆固醇氧化物,可用作脂质过氧化的生物标志物。
T7982 3,6-Dihydroxyflavone

Others Others
3,6-Dihydroxyflavone 是一种抗癌剂。它能够提高细胞内氧化应激和脂质过氧化。它是能够根据剂量和时间依赖性地降低细胞活力,并活化半胱天冬酶级联、切割聚 (ADP-核糖) 聚合酶 (PARP) 诱导细胞凋亡。
T3804 Neomangiferin

Mangiferin 7-glucoside,新芒果苷

Phosphatase Metabolism
Neomangiferin (Mangiferin 7-glucoside) 是一种天然的 C-glucosyl xanthone,分离自干燥的Anemarrhena asphodeloides 的根茎中。它能够减轻大鼠高脂饮食诱导的非酒精性脂肪性肝病 (NAFLD)。
TN2158 Robinetin

3,3',4',5',7-Pentahydroxyflavone,洋槐黄素

Anti-infection; HIV Protease; Antibacterial Microbiology/Virology; Proteases/Proteasome
Robinetin (3,3',4',5',7-Pentahydroxyflavone) 是一种天然黄酮,具有显著的“两种颜色”固有荧光特性。它具有抗真菌、抗病毒、抗菌、抗突变、抗氧化和抗自由基活性,高效抑制 EYPC 膜脂质过氧化和 HbA 糖基化。
T0683 Mevastatin

Compactin,ML236B,美伐他汀

Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid Apoptosis; Autophagy; Metabolism; Microbiology/Virology
Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药,可诱导细胞凋亡,将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性,用于心血管疾病的研究。
T0626 Uric Acid

尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Reactive Oxygen Species; Endogenous Metabolite; Phosphorylase Immunology/Inflammation; Metabolism; NF-κB
Uric Acid (Lithic acid) 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ,如单线态氧和过氧亚硝酸盐,抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T0700 Ursodeoxycholic acid

熊去氧胆酸,UDCA,Ursodiol

Potassium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
Ursodeoxycholic acid (UDCA)是一种有效的肝脏特异性脂肪酸转运蛋白 5 (FATP5) 抑制剂,通过 FATP5 依赖性方式抑制原代肝细胞摄取长链脂肪酸。Ursodeoxycholic acid 能够抑制胆固醇的吸收,用于溶解胆结石,并具有研究与肥胖相关的脂肪肝疾病的潜力。
T4S1173 Agrimol B

仙鹤草酚B,仙鹤草酚 B

Sirtuin; PPAR Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Agrimol B 是从仙鹤草中分离得到的一种多酚衍生物,可抑制脂肪形成,降低PPARγ的表达,诱导SIRT1易位和表达。
T9525 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC)

Others Others
1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) 是一种用于脂质体和脂质双层的合成磷脂。它可用于脂质单层和双层的研究。
T37710 5-Hydroxyoxindole

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
5-Hydroxyoxindole 是尿酸的一种结构类似物,具有脂质过氧化抑制活性和自由基 DPPH 清除活性,可用于氧化应激介导的疾病的研究。
T9510 1,2-Distearoyl-sn-glycero-3-phosphorylcholine

DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC,二硬脂酰磷脂酰胆碱

Others Others
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) 是一种脂质纳米颗粒(LNP) 系统中的脂质成分,可用于合成脂质体。
T19085 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC

POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine

Others Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。
T29078 Ursodeoxycholic acid sodium

UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,熊去氧胆酸钠盐,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium

FXR; Endogenous Metabolite; GPCR19 GPCR/G Protein; Metabolism
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) 是一种天然存在的次级胆汁酸,具有抗炎和细胞保护活性。Ursodeoxycholic acid sodium 作为信号分子,通过与胆汁酸激活受体相互作用发挥其作用,包括 G 蛋白偶联胆汁酸受体 5 (TGR5) 和法尼醇 X 受体 (FXR)。
T38141 Glycerophospholipids, cephalins

Phosphatidylethanolamines (egg)

Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T38949 Gingerglycolipid A

Others Others
Gingerglycolipid A is a monoacyldigalactosyl glycerol.
T1035 Hesperidin

橙皮甙,Hesperetin 7-rutinoside,Cirantin,橙皮苷

Apoptosis; Reactive Oxygen Species; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Hesperidin (Cirantin) 属于黄烷酮糖苷类天然产物,广泛存在于柑橘类水果中。Hesperidin 具有抗氧化活性、抗肿瘤活性和抗过敏活性。
TN1644 Flavanomarein

Others Others
Flavanomarein 是Coreopsis tinctoria Nutt 的主要黄酮类化合物,对糖尿病性肾病具有保护作用。它具有很好的抗氧化,降糖,降压和降血脂作用。
T4957 Carnosic acid

Apoptosis; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Carnosic acid 抑制细胞增殖,有抗菌、抗炎和抗氧化应激作用。
TN4973 Sculponeatin O

Others Others
Sculponeatin O 是一种 ent-kaurane 二萜衍生物,分离自 Isodon sculponeata 植物。
T16747 Riboflavin Tetrabutyrate

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Riboflavin Tetrabutyrate 是一种亲脂性黄素衍生物,具有抗氧化和脂质过氧化物去除活性。
T8714 1-Stearoyl-sn-glycero-3-phosphocholine

1-硬脂酰-SN-甘油-3-磷酰胆碱,1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY

Others Others
1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) 是一种用于脂质代谢研究的化学物质。
T19316 Ethyl oleate

Others Others
Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。
T19564 Stearoylcarnitine

Stearoyl-L-carnitine

Endogenous Metabolite Metabolism
Stearoylcarnitine (Stearoyl-L-carnitine) 是一种脂肪酯脂质分子,是一种人内源代谢产物,可作为早发型子痫前期和晚发性子痫前期的生物标志物。
T4857 Pteridine-2,4(1H,3H)-dione

2,4-Dihydroxypteridine,2,4-二羟基蝶啶,Lumazine

Others; Endogenous Metabolite Metabolism; Others
Pteridine-2,4(1H,3H)-dione (Lumazine) 是内源性代谢产物的一种。
T0800 Danthron

Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol

Virus Protease; Antibacterial; AMPK; Autophagy Autophagy; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling
Danthron (Antrapurol) 是一种从中药 rhubarb 中提取的天然产物,可通过激活 AMPK 来调节葡萄糖和脂质代谢。
TN3120 5-Hydroxy-7-acetoxy-8-methoxyflavone

Histone Demethylase; Antiviral Chromatin/Epigenetic; Immunology/Inflammation
5-Hydroxy-7-acetoxy-8-methoxyflavone 是一种类黄酮化合物,可以抑制脂质过氧化,可能具有抗流感病毒活性。
T2867 Diosgenin

山药,Nitogenin

STAT JAK/STAT signaling; Stem Cells
Diosgenin (Nitogenin) 是盾叶薯蓣中的一种甾体皂苷,是Pdia3/ERp57的激活剂,能够抑制STAT3信号通路。
TN1863 Licoisoflavone A

Phaseoluteone

MRP Immunology/Inflammation
Licoisoflavone A (Phaseoluteone) 是一种 MRP 抑制剂,可抑制脂质过氧化,IC50 为 7.2 μM。
T4461 3,5-Diiodo-L-thyronine

3,5-二碘-L-甲状腺素,Diiodothyronine

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
3,5-Diiodo-L-thyronine (Diiodothyronine) 是内源性代谢产物的一种。
T0595 Naringin

Naringoside,柚皮苷

Mitophagy; P450; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Naringin (Naringoside) 是一种黄烷酮糖苷,有抗氧化活性、降血脂、抗癌和抑制细胞色素P450酶的药理作用。
T3376 Cynaroside

朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside

Others; Influenza Virus; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
Cynaroside (Luteolin 7-O-Glucoside) 是一个抗氧化类黄酮。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 32 nM。
T4241 Rubiadin

1,3-Dihydroxy-2-Methylanthracene-9,10-Dione,茜根定,茜草素

Free radical scavengers; PARP; Caspase Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; oxidation-reduction; Proteases/Proteasome
Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) 是一种二羟基蒽醌,提取自茜草,具有抗氧化剂作用。
T7773 DPPC

1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL,二棕榈酸磷脂酰胆碱,129Y83

Endogenous Metabolite Metabolism
DPPC (129Y83) 是一种磷酸甘油酯,能够用于制备脂质体单层。DPPC-脂质体能够用作小鼠中诱导针对 GSL 抗原的免疫应答的递送载体。
TN7233 Pseudobaptigenin

Psi-baptigenin

Others Others
Pseudobaptigenin (Psi-baptigenin) 是一种异黄酮,是一种黄酮类脂质分子,是在Pterocarpus marsupium、Dalbergia spruceana 中发现的一种天然产品。
T14149 AICAR phosphate

AICA Riboside phosphate,Acadesine phosphate

Mitophagy; NOS; YAP; AMPK Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Stem Cells
AICAR phosphate (Acadesine phosphate) 是 AMPK 激活剂且是自噬、YAP 和 mitophagy 抑制剂,也是一种腺苷类似物, 可调节糖代谢和脂代谢,抑制促炎细胞因子和 iNOS 的产生。
TMA2440 Uridine 5'-monophosphate disodium salt

尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Others Others
Uridine 5'-monophosphate disodium salt (Disodium UMP) 是合成 RNA 的一种重要成分。
T19237 Cholesteryl oleate

胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate

Endogenous Metabolite Metabolism
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) 是胆固醇的酯化形式,可用于合成固体脂质纳米颗粒。
T0539 Dihydrocaffeic acid

二氢咖啡酸,Hydrocaffeic acid

Antioxidant; p38 MAPK; Endogenous Metabolite MAPK; Metabolism; oxidation-reduction
Dihydrocaffeic acid 是绿原酸的代谢物,是一种众所周知的抗氧化成分,具有抗氧化、抗阿尔茨海默病、神经保护、唤醒和降脂作用。
T5613 Squalane

角鲨烷,Dodecahydrosqualene,Perhydrosqualene

Others Others
Squalane 是某些鱼油 (尤其是鲨鱼肝油) 和某些植物油中存在的脂质。它具有抗癌,抗氧化作用,可用作皮肤保湿和润肤剂。
T16075 (Rac)-Idroxioleic acid

2-Hydroxyoleic acid,2-OHOA,2-羟基乳清酸,Minerval

Apoptosis Apoptosis
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) 是一种具有抗肿瘤作用的脂肪酸酰胺水解酶抑制剂。 它与质膜结合并改变脂质组织。
T41031 Protamine sulfate

Thrombin Proteases/Proteasome
Protamine sulfate是一种多阳离子肽类,作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。
T11855 Lipopolysaccharides

脂多糖,LPS

Others Others
Lipopolysaccharides (LPS) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T41078 Lipopolysaccharides, Escherichiacoli

Lipopolysaccharide, E. coli O111:B4

Others Others
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T1039 Choline chloride

Biocolina,Biocoline,Hepacholine,氯化胆碱

AChR Neuroscience
Choline chloride (Biocoline) 是一种必需营养素,可激活 α7 烟碱受体,具有抗炎、镇痛的活性。对动脉粥样硬化、神经系统疾病和肝脏疾病等具有影响。
T19792 1,3,7-Trimethyluric acid

Others Others
1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。
TN1962 Myricetin 3-O-galactoside

Myricetin 3-O-beta-D-galactopyranoside

NOS; Xanthine Oxidase Immunology/Inflammation; Metabolism
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) 可抑制黄嘌呤氧化酶 (xanthine oxidase; XO) 活性,脂质过氧化并清除自由基。杨梅素3- o -半乳糖苷具有很多作用包括细胞毒性、抗氧化、抗基因毒性、抗感染性、抗炎作用和抗氧化活性,其主要作用是抑制诱导型一氧化氮合酶(iNOS)的合成。Myricetin 3-O-galactoside 抑制脂质过氧化的 IC50 为 160 μg/mL。
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天然产物

Kdo2-Lipid A ammonium
Cat.No: T38635
Synonym:
Target: TNF, TLR, Prostaglandin Receptor
Pedunculoside
Cat.No: T2824
Synonym:
Target: Others, Fatty Acid Synthase
Malabaricone C
Cat.No: TN6772
Synonym:
Target: Others
4-Hydroxyflavanone
Cat.No: T7992
Synonym:
Target: NO Synthase
7α-Hydroxycholesterol
Cat.No: T19161
Synonym:
Target: Others
3,6-Dihydroxyflavone
Cat.No: T7982
Synonym:
Target: Others
Neomangiferin
Cat.No: T3804
Synonym: Mangiferin 7-glucoside,新芒果苷
Target: Phosphatase
Robinetin
Cat.No: TN2158
Synonym: 3,3',4',5',7-Pentahydroxyflavone,洋槐黄素
Target: Anti-infection, HIV Protease, Antibacterial
Mevastatin
Cat.No: T0683
Synonym: Compactin,ML236B,美伐他汀
Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid
Uric Acid
Cat.No: T0626
Synonym: 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate
Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase
Ursodeoxycholic acid
Cat.No: T0700
Synonym: 熊去氧胆酸,UDCA,Ursodiol
Target: Potassium Channel, Endogenous Metabolite
Agrimol B
Cat.No: T4S1173
Synonym: 仙鹤草酚B,仙鹤草酚 B
Target: Sirtuin, PPAR
1,2-Dimyristoyl-sn-glycero-3-phosphocholine
Cat.No: T9525
Synonym: DMPC,1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOL,二肉豆蔻酰磷脂酰胆碱(DMPC)
Target: Others
5-Hydroxyoxindole
Cat.No: T37710
Synonym:
Target: Reactive Oxygen Species
1,2-Distearoyl-sn-glycero-3-phosphorylcholine
Cat.No: T9510
Synonym: DSPC,L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL,1,2-Distearoyl-sn-glycero-3-PC,二硬脂酰磷脂酰胆碱
Target: Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
Cat.No: T19085
Synonym: POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine
Target: Others
Ursodeoxycholic acid sodium
Cat.No: T29078
Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,熊去氧胆酸钠盐,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium
Target: FXR, Endogenous Metabolite, GPCR19
Glycerophospholipids, cephalins
Cat.No: T38141
Synonym: Phosphatidylethanolamines (egg)
Target:
Gingerglycolipid A
Cat.No: T38949
Synonym:
Target: Others
Hesperidin
Cat.No: T1035
Synonym: 橙皮甙,Hesperetin 7-rutinoside,Cirantin,橙皮苷
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite, Autophagy
Flavanomarein
Cat.No: TN1644
Synonym:
Target: Others
Carnosic acid
Cat.No: T4957
Synonym:
Target: Apoptosis, ROS, Antibacterial
Sculponeatin O
Cat.No: TN4973
Synonym:
Target: Others
Riboflavin Tetrabutyrate
Cat.No: T16747
Synonym:
Target: Reactive Oxygen Species
1-Stearoyl-sn-glycero-3-phosphocholine
Cat.No: T8714
Synonym: 1-硬脂酰-SN-甘油-3-磷酰胆碱,1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY
Target: Others
Ethyl oleate
Cat.No: T19316
Synonym:
Target: Others
Stearoylcarnitine
Cat.No: T19564
Synonym: Stearoyl-L-carnitine
Target: Endogenous Metabolite
Pteridine-2,4(1H,3H)-dione
Cat.No: T4857
Synonym: 2,4-Dihydroxypteridine,2,4-二羟基蝶啶,Lumazine
Target: Others, Endogenous Metabolite
Danthron
Cat.No: T0800
Synonym: Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol
Target: Virus Protease, Antibacterial, AMPK, Autophagy
5-Hydroxy-7-acetoxy-8-methoxyflavone
Cat.No: TN3120
Synonym:
Target: Histone Demethylase, Antiviral
Diosgenin
Cat.No: T2867
Synonym: 山药,Nitogenin
Target: STAT
Licoisoflavone A
Cat.No: TN1863
Synonym: Phaseoluteone
Target: MRP
3,5-Diiodo-L-thyronine
Cat.No: T4461
Synonym: 3,5-二碘-L-甲状腺素,Diiodothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Naringin
Cat.No: T0595
Synonym: Naringoside,柚皮苷
Target: Mitophagy, P450, Endogenous Metabolite, Autophagy
Cynaroside
Cat.No: T3376
Synonym: 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside
Target: Others, Influenza Virus, DNA/RNA Synthesis
Rubiadin
Cat.No: T4241
Synonym: 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione,茜根定,茜草素
Target: Free radical scavengers, PARP, Caspase
DPPC
Cat.No: T7773
Synonym: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL,二棕榈酸磷脂酰胆碱,129Y83
Target: Endogenous Metabolite
Pseudobaptigenin
Cat.No: TN7233
Synonym: Psi-baptigenin
Target: Others
AICAR phosphate
Cat.No: T14149
Synonym: AICA Riboside phosphate,Acadesine phosphate
Target: Mitophagy, NOS, YAP, AMPK
Uridine 5'-monophosphate disodium salt
Cat.No: TMA2440
Synonym: 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate
Target: Others
Cholesteryl oleate
Cat.No: T19237
Synonym: 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate
Target: Endogenous Metabolite
Dihydrocaffeic acid
Cat.No: T0539
Synonym: 二氢咖啡酸,Hydrocaffeic acid
Target: Antioxidant, p38 MAPK, Endogenous Metabolite
Squalane
Cat.No: T5613
Synonym: 角鲨烷,Dodecahydrosqualene,Perhydrosqualene
Target: Others
(Rac)-Idroxioleic acid
Cat.No: T16075
Synonym: 2-Hydroxyoleic acid,2-OHOA,2-羟基乳清酸,Minerval
Target: Apoptosis
Protamine sulfate
Cat.No: T41031
Synonym:
Target: Thrombin
Lipopolysaccharides
Cat.No: T11855
Synonym: 脂多糖,LPS
Target: Others
Lipopolysaccharides, Escherichiacoli
Cat.No: T41078
Synonym: Lipopolysaccharide, E. coli O111:B4
Target: Others
Choline chloride
Cat.No: T1039
Synonym: Biocolina,Biocoline,Hepacholine,氯化胆碱
Target: AChR
1,3,7-Trimethyluric acid
Cat.No: T19792
Synonym:
Target: Others
Myricetin 3-O-galactoside
Cat.No: TN1962
Synonym: Myricetin 3-O-beta-D-galactopyranoside
Target: NOS, Xanthine Oxidase
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Cat. No. Product Name Species Expression System
TMPH-00791 NsLTP Protein, Helianthus annuus, Recombinant (His & Myc)

Non-specific lipid-transfer protein,SDI-9

Helianthus annuus E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. NsLTP Protein, Helianthus annuus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is Q39950.
TMPH-02450 MALD3 Protein, Malus domestica, Recombinant (His & SUMO)

Non-specific lipid-transfer protein,MALD3

Apple E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. MALD3 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 25.1 kDa and the accession number is Q9M5X7.
TMPH-00736 LpxK Protein, E. coli, Recombinant (His & Myc)

Tetraacyldisaccharide 4'-kinase,Lipid A 4'-kinase,l...

E. coli E. coli
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
TMPH-02379 arnT Protein, Klebsiella pneumoniae, Recombinant (His)

Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase...

Klebsiella pneumoniae E. coli
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
TMPH-03085 LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)

Allergen Par j II,Probable non-specific lipid-trans...

Parietaria judaica E. coli
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is P55958.
TMPH-00846 ABHD5 Protein, Human, Recombinant (His & SUMO)

Abhydrolase domain-containing protein 5,1-acylglycerol-3-pho...

Human E. coli
ABHD5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.0 kDa and the accession number is Q8WTS1.
TMPJ-00529 FABP6 Protein, Human, Recombinant (His)

Ileal Lipid-Binding Protein,I-BABP,Intestinal Bile ...

Human E. coli
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level)...
TMPJ-00671 FABP7 Protein, Human, Recombinant (His)

Fatty Acid-Binding Protein 7,Mammary-Derived Growth Inhibito...

Human E. coli
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknow...
TMPH-01996 LAMTOR1 Protein, Human, Recombinant (His)

LAMTOR1,Late endosomal/lysosomal adaptor and MAPK and MTOR a...

Human E. coli
LAMTOR1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01780 SCP2 Protein, Human, Recombinant (GST)

Sterol carrier protein 2,Propanoyl-CoA C-acyltransferase,SCP...

Human E. coli
SCP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.4 kDa and the accession number is P22307.
TMPK-00831 Galectin-3 Protein, Mouse, Recombinant (His)

Galectin3,LGALS2,AGE-R3,L31,LGALS3,Mac-2,GAL3,L29,Gal-3,GALI...

Mouse HEK293 Cells
Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.
TMPH-02646 Erythroferrone Protein, Mouse, Recombinant (His)

Erythroferrone,Myonectin,Erfe,Complement C1q tumor necrosis ...

Mouse P. pastoris (Yeast)
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Erythroferrone Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted m...
TMPY-00395 Insulin Protein, Human, Recombinant

IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS

Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ...
TMPY-02204 LBP Protein, Human, Recombinant (His)

BPIFD2,lipopolysaccharide binding protein

Human HEK293 Cells
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end...
TMPY-02575 PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

CIMT1,PPARγ,GLM1,PPARgamma,PPARG1,PPARG2,NR1C3,peroxisome pr...

Human Baculovirus Insect Cells
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. Peroxisome proli...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)

APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L

Human Baculovirus Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer...
TMPY-02585 Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)

aSMase,ASM,Zn-SMase,A-SMase,sphingomyelin phosphodiesterase ...

Mouse Baculovirus Insect Cells
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monome...
TMPH-03048 LpxA Protein, MenC, Recombinant (His)

lpxA,Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-...

MenB E. coli
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
TMPH-00174 MURG Protein, Bacillus subtilis, Recombinant (His)

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyro...

Bacillus subtilis E. coli
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). MURG Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.9 kDa and the accession number is P37585.
TMPH-00555 LpxC Protein, E. coli, Recombinant (His)

lpxC,UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[R...

E. coli E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPK-00589 Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)

APOE,apolipo E,Apo-E,APOE4,Apolipoprotein E

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPK-00788 Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)

apolipo E,Apo-E,Apolipoprotein E,APOE

Mouse HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells wi...
TMPH-02378 LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)

UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[R-3-hy...

Klebsiella pneumoniae E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPJ-01368 GPC1 Protein, Mouse, Recombinant (His)

Gpc1,Glypican-1

Mouse HEK293 Cells
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated sig...
TMPK-00762 Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)

APOE,Apo-E,Apolipoprotein E,APOE3,apolipo E

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPH-01296 GPX5 Protein, Human, Recombinant (GST & His)

GPX5,Glutathione peroxidase 5,Epididymal secretory glutathio...

Human E. coli
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
TMPK-00763 Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

APOE3,Apo-E,apolipo E,Apolipoprotein E,APOE

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated i...
TMPK-00588 Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)

Apolipoprotein E,Apo-E,apolipo E,APOE4,APOE

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPH-02667 Galactosylceramidase Protein, Mouse, Recombinant

Galactocerebroside beta-galactosidase,Galactocerebrosidase,G...

Mouse E. coli
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
TMPY-02885 CD1B Protein, Human, Recombinant (hFc)

CD1,CD1A,CD1b molecule,R1,CD1B

Human HEK293 Cells
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. During protein synthesis and maturation, they bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface. CD...
TMPH-02518 APOM Protein, Mouse, Recombinant (His)

Ng20,ApoM,Apolipoprotein M,Apo-M

Mouse P. pastoris (Yeast)
Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. APOM Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.3 kDa and the accession number is Q9Z1R3.
TMPH-00024 LpxC Protein, Acinetobacter baumannii, Recombinant (His)

UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[R-3-hy...

Acinetobacter baumannii E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Acinetobacter baumannii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is B2I1I9.
TMPH-03180 LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

UDP-3-O-acyl-N-acetylglucosamine deacetylase,lpxC,UDP-3-O-[R...

Pseudomonas aeruginosa E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.4 kDa and the accession number is P47205.
TMPH-00831 PMP2 Protein, Horse, Recombinant (His & SUMO)

PMP2,Myelin P2 protein

Horse E. coli
May play a role in lipid transport protein in Schwann cells. May bind cholesterol. PMP2 Protein, Horse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is P0C6G6.
TMPJ-00715 FGF-19 Protein, Human, Recombinant (His)

FGF-19,Fibroblast growth factor 19,FGF19

Human E. coli
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ...
TMPH-00648 LapB Protein, E. coli, Recombinant (His)

Lipopolysaccharide assembly protein B,lapB,Lipopolysaccharid...

E. coli E. coli
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
TMPH-02181 CD1C Protein, Human, Recombinant (His)

T-cell surface glycoprotein CD1c,CD1C

Human E. coli
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. CD1C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.2 kDa and the accession number is P29017.
TMPH-03044 PBP1a Protein, MenB, Recombinant (His & SUMO)

mrcA,Penicillin-binding protein 1A

MenB E. coli
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
TMPH-02306 VTI1B Protein, Human, Recombinant (His & SUMO)

Vti1-rp1,VTI1B,Vesicle transport through interaction with t-...

Human E. coli
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
TMPH-01301 Erythroferrone Protein, Human, Recombinant (His & SUMO)

Myonectin,Erythroferrone,ERFE,Complement C1q tumor necrosis ...

Human E. coli
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake.
TMPH-03401 Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Rat, Recombinant (His & Myc)

Azgp1,Zinc-alpha-2-glycoprotein

Rat E. coli
Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.7 kDa and the accession number is Q63678.
TMPY-04423 CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)

VWS1,RP1-272L16.2,calcium/calmodulin-dependent protein kinas...

Human Baculovirus Insect Cells
Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular responses. Calcium binds to calcium binding proteins (calmodulin/CaM) and stimulates the activity of a variety of enzymes, including CaM kinases referred to as CaM-kinases (CaMKs), such as CaMKI, CaMKII, CaMKIV and CaMKK. Calmodulin-dependent protein kinase CL3/CaMKIγ is a membera...
TMPJ-01302 ACAT2 Protein, Human, Recombinant (His)

ACTL,Acetyl-CoA transferase-like protein,Acetyl-CoA acetyltr...

Human E. coli
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2 deficiency contributes to severe mental retardation and hypotonus.
TMPH-02509 ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)

Angiopoietin-like protein 8,Lipasin,Gm6484,Refeeding-induced...

Mouse E. coli
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3.
TMPH-03179 LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetyla...

Pseudomonas aeruginosa E. coli
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.4 kDa and the accession number is A6VB79.
TMPH-00670 MscL Protein, E. coli O157:H7, Recombinant (B2M & His)

mscL,Large-conductance mechanosensitive channel

E. coli E. coli
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. MscL Protein, E. coli O157:H7, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 29.0 kDa and the accession number is P0A743.
TMPY-01563 PMP2 Protein, Human, Recombinant (His)

MP2,FABP8,peripheral myelin protein 2,P2,M-FABP

Human E. coli
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ...
TMPY-01140 ACOT13/THEM2 Protein, Human, Recombinant (His)

THEM2,HT012,ACOT13,PNAS-27,acyl-CoA thioesterase 13

Human E. coli
The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their biological functions remain incompletely understood. Thioesterase superfamily member 2 (Them2; synonym Acot13) is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. Using Them2(-/-) m...
TMPK-00123 CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated

Leu2,CD8 α/CD8A,MAL,Lyt-2,OKT8 T-cell antigen,CD8a molecule,...

Human HEK293 Cells
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
TMPH-00701 PBP1b Protein, E. coli, Recombinant (His & Myc)

Penicillin-binding protein 1B,Murein polymerase,mrcB

E. coli E. coli
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). PBP1b Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.6 kDa and the accession number is P02919...
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重组蛋白

NsLTP Protein, Helianthus annuus, Recombinant (His & Myc)
Cat.No: TMPH-00791
Species: Helianthus annuus
Expression System: E. coli
MALD3 Protein, Malus domestica, Recombinant (His & SUMO)
Cat.No: TMPH-02450
Species: Apple
Expression System: E. coli
LpxK Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00736
Species: E. coli
Expression System: E. coli
arnT Protein, Klebsiella pneumoniae, Recombinant (His)
Cat.No: TMPH-02379
Species: Klebsiella pneumoniae
Expression System: E. coli
LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)
Cat.No: TMPH-03085
Species: Parietaria judaica
Expression System: E. coli
ABHD5 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00846
Species: Human
Expression System: E. coli
FABP6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00529
Species: Human
Expression System: E. coli
FABP7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00671
Species: Human
Expression System: E. coli
LAMTOR1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01996
Species: Human
Expression System: E. coli
SCP2 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01780
Species: Human
Expression System: E. coli
Galectin-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00831
Species: Mouse
Expression System: HEK293 Cells
Erythroferrone Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02646
Species: Mouse
Expression System: P. pastoris (Yeast)
Insulin Protein, Human, Recombinant
Cat.No: TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
LBP Protein, Human, Recombinant (His)
Cat.No: TMPY-02204
Species: Human
Expression System: HEK293 Cells
PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02575
Species: Human
Expression System: Baculovirus Insect Cells
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02956
Species: Human
Expression System: Baculovirus Insect Cells
Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02585
Species: Mouse
Expression System: Baculovirus Insect Cells
LpxA Protein, MenC, Recombinant (His)
Cat.No: TMPH-03048
Species: MenB
Expression System: E. coli
MURG Protein, Bacillus subtilis, Recombinant (His)
Cat.No: TMPH-00174
Species: Bacillus subtilis
Expression System: E. coli
LpxC Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00555
Species: E. coli
Expression System: E. coli
Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)
Cat.No: TMPK-00589
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00788
Species: Mouse
Expression System: HEK293 Cells
LpxC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)
Cat.No: TMPH-02378
Species: Klebsiella pneumoniae
Expression System: E. coli
GPC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01368
Species: Mouse
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00762
Species: Human
Expression System: HEK293 Cells
GPX5 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01296
Species: Human
Expression System: E. coli
Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00763
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00588
Species: Human
Expression System: HEK293 Cells
Galactosylceramidase Protein, Mouse, Recombinant
Cat.No: TMPH-02667
Species: Mouse
Expression System: E. coli
CD1B Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02885
Species: Human
Expression System: HEK293 Cells
APOM Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02518
Species: Mouse
Expression System: P. pastoris (Yeast)
LpxC Protein, Acinetobacter baumannii, Recombinant (His)
Cat.No: TMPH-00024
Species: Acinetobacter baumannii
Expression System: E. coli
LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Cat.No: TMPH-03180
Species: Pseudomonas aeruginosa
Expression System: E. coli
PMP2 Protein, Horse, Recombinant (His & SUMO)
Cat.No: TMPH-00831
Species: Horse
Expression System: E. coli
FGF-19 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00715
Species: Human
Expression System: E. coli
LapB Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00648
Species: E. coli
Expression System: E. coli
CD1C Protein, Human, Recombinant (His)
Cat.No: TMPH-02181
Species: Human
Expression System: E. coli
PBP1a Protein, MenB, Recombinant (His & SUMO)
Cat.No: TMPH-03044
Species: MenB
Expression System: E. coli
VTI1B Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02306
Species: Human
Expression System: E. coli
Erythroferrone Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01301
Species: Human
Expression System: E. coli
Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03401
Species: Rat
Expression System: E. coli
CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04423
Species: Human
Expression System: Baculovirus Insect Cells
ACAT2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01302
Species: Human
Expression System: E. coli
ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02509
Species: Mouse
Expression System: E. coli
LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03179
Species: Pseudomonas aeruginosa
Expression System: E. coli
MscL Protein, E. coli O157:H7, Recombinant (B2M & His)
Cat.No: TMPH-00670
Species: E. coli
Expression System: E. coli
PMP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01563
Species: Human
Expression System: E. coli
ACOT13/THEM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01140
Species: Human
Expression System: E. coli
CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated
Cat.No: TMPK-00123
Species: Human
Expression System: HEK293 Cells
PBP1b Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00701
Species: E. coli
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T69462 Deulinoleic acid

Deulinoleic acid is a lipid peroxidation inhibitor and antioxidant.
T36149 13C C16 Sphingomyelin (d18:1/16:0)

13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. It is intended for use as an internal standard for the quantification of C16 sphingomyelin by GC- or LC-MS. C16 Sphingomyelin is a form of sphingomyelin containing palmitate (16:0) at the variable acylation position. It is the most common form of sphingomyelin found in eggs and is less abundant in the brain and in milk. C16 Sphingomyelin interacts with cholesterol in or...
T37044 1,2-Dioleoyl-rac-glycerol-13C3

1,2-Dioleoyl-rac-glycerol-13C3

1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 |1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-reg...
T71326 1,3,7-Trimethyluric Acid-d9

1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.
TMIJ-0079 N-Carbobenzyloxyglycine-d2

N-Carbobenzyloxyglycine-d2 是 N-Carbobenzyloxyglycine 的氘代化合物。N-Carbobenzyloxyglycine 的 CAS 号为 1138-80-3。Z-Glycine (Carbobenzoxyglycine) 是一种药物-脂质结合物,旨在促进脑渗透,基于其亲脂性和与生物膜中脂质的相似性。
T38356 1,2-Dipalmitoyl-13C-sn-glycero-3-PC

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...
T35778 Ochratoxin A-13C20

Ochratoxin A-13C20

Ochratoxin A-13C20is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1phase, and apoptosis in mouse ...
T69395 Nicotinamide-d4

Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl...
TMIH-0109 Bempedoic acid-d4

Bempedoic acid-d4 是 Bempedoic acid 的氘代化合物。Bempedoic acid 的 CAS 号为 738606-46-7。ETC-1002 是一种 ATP-柠檬酸裂解酶抑制剂,可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...

同位素标记化合物

Deulinoleic acid
Cat.No: T69462
Synonym:
Target:
13C C16 Sphingomyelin (d18:1/16:0)
Cat.No: T36149
Synonym:
Target:
1,2-Dioleoyl-rac-glycerol-13C3
Cat.No: T37044
Synonym: 1,2-Dioleoyl-rac-glycerol-13C3
Target:
1,3,7-Trimethyluric Acid-d9
Cat.No: T71326
Synonym:
Target:
N-Carbobenzyloxyglycine-d2
Cat.No: TMIJ-0079
Synonym:
Target:
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
Cat.No: T38356
Synonym:
Target:
Ochratoxin A-13C20
Cat.No: T35778
Synonym: Ochratoxin A-13C20
Target:
Nicotinamide-d4
Cat.No: T69395
Synonym:
Target:
Bempedoic acid-d4
Cat.No: TMIH-0109
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
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