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Search Results for " leukotriene a4 hydrolase "

Targets Recommended: Aminopeptidase

12

抑制剂 & 化合物

3

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T21696	SC-57461A N -甲基- N -[3 - [4 - (苯甲基)苯氧基]丙基Β-丙氨酸盐酸盐	Aminopeptidase	Metabolism
	SC-57461A 是一种口服有活力的非肽类白三烯 A4 (LTA4) 水解酶选择性抑制剂，它能够抑制重组人 (IC50: 2.5 nM) 、小鼠 (IC50: 3 nM) 和小鼠LTA4水解酶 (IC50: 23 nM) 。
TQ0047	DG051	Aminopeptidase	Metabolism
	DG051 是有效的白三烯 A4 水解酶抑制剂，IC50=47 nM。
T28698	SC-22716 SC 22716,SC22716	Aminopeptidase	Metabolism
	SC-22716 是一种具有口服活性的白三烯 A4（LTA4）水解酶抑制剂。SC-22716 具有潜在的抗炎活性，可用于研究炎症性肠病和银屑病。
T3715	Acebilustat 阿西鲁司特,CTX-4430	Aminopeptidase; LTR	Immunology/Inflammation; Metabolism
	Acebilustat (CTX-4430) 是一种具有口服活性的白三烯 A4 水解酶抑制剂，可用于炎症研究。
T6301	Tosedostat CHR-2797,托舍多特	Aminopeptidase; AChR	Metabolism; Neuroscience
	Tosedostat (CHR-2797) 是一种具有口服活性的氨基肽酶(aminopeptidase) 抑制剂，对多种肿瘤细胞系均具有抗增殖作用。
T68595	JNJ-26993135	Others	Others
	JNJ-26993135 is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor.
T19047	PL553	Others	Others
	PL553 is a specific and high-affinity fluorogenic substrate of Leukotriene A4 hydrolase (λmax: 210 nm; λem: 410 nm).
T68314	DG-051	Others	Others
	DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.
T9690	LTA4H-IN-1 LYS-006	Others	Others
	LTA4H-IN-1 是一种有效的白三烯 A4 水解酶LTA4H 抑制剂，IC50值为 2 nM，可用于炎症和自身免疫性疾病研究。
T86827	LTA4H-IN-2
	Compound (S)-2 (LTA4H-IN-2) 为具有口服活性的白三烯A4水解酶抑制剂，显示出极低的IC50值，小于3 nM。
T37652	5(S),6(R)-DiHETE	Others	Others
	5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It is a weak LTD4 receptor agonist in guinea pig lung membranes. It induces guinea pig ileum contraction with an ED50 value of 1.3 μM.
T37970	12-epi Leukotriene B4 12-epi Leukotriene B4	Others	Others
	Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are 50:50 mixtures at C-12, but are almost exclusively trans at C-6. Thus, the non-enzymatic hydrolysis product of LTA4 is 6-trans-12-epi LTB4. 12-epi LTB4 is an isomer which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic pr...

化合物

Cat.No: T21696

Synonym: N -甲基- N -[3 - [4 - (苯甲基)苯氧基]丙基Β-丙氨酸盐酸盐

Target: Aminopeptidase

Cat.No: TQ0047

Target: Aminopeptidase

Cat.No: T28698

Synonym: SC 22716,SC22716

Target: Aminopeptidase

Cat.No: T3715

Synonym: 阿西鲁司特,CTX-4430

Target: Aminopeptidase, LTR

Cat.No: T6301

Synonym: CHR-2797,托舍多特

Target: Aminopeptidase, AChR

Cat.No: T68595

Target: Others

Cat.No: T19047

Target: Others

Cat.No: T68314

Target: Others

Cat.No: T9690

Synonym: LYS-006

Target: Others

Cat.No: T86827

5(S),6(R)-DiHETE

Cat.No: T37652

Target: Others

12-epi Leukotriene B4

Cat.No: T37970

Synonym: 12-epi Leukotriene B4

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3529	Bestatin hydrochloride 盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素	Integrin; Aminopeptidase; Antibacterial; Antibiotic	Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Bestatin hydrochloride (Ubenimex hydrochloride) 是CD13(Aminopeptidase N)/APN 和leukotriene A4 hydrolase 抑制剂，可研究癌症。
T1257	Bestatin Ubenimex,乌苯美司	Others; Aminopeptidase; Antibacterial; Antibiotic; LTR	Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
	Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂，可用于癌症研究。
T62258	Bestatin trifluoroacetate	Others	Others
	Bestatin trifluoroacetate (Ubenimex trifluoroacetate) 是一种 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂，经常用于研究癌症。

天然产物

Bestatin hydrochloride

Cat.No: T3529

Synonym: 盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素

Target: Integrin, Aminopeptidase, Antibacterial, Antibiotic

Cat.No: T1257

Synonym: Ubenimex,乌苯美司

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

Bestatin trifluoroacetate

Cat.No: T62258

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01658	Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His) Lta4h,leukotriene A4 hydrolas...	Mouse	Baculovirus Insect Cells
	Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.4 kDa and the accession number is P24527.
TMPY-00877	Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) LAT4,leukotriene A4 hydrolase	Human	Baculovirus Insect Cells
	Leukotriene A4 Hydrolase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.7 kDa and the accession number is A0A140VK27.

重组蛋白

Leukotriene A4 Hydrolase Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01658

Species: Mouse

Expression System: Baculovirus Insect Cells

Leukotriene A4 Hydrolase Protein, Human, Recombinant (His)

Cat.No: TMPY-00877

Species: Human

Expression System: Baculovirus Insect Cells

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