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Search Results for " larvicidal "

Targets Recommended: Parasite

9

抑制剂 & 化合物

13

天然产物

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T2180	Hexythiazox	Parasite	Microbiology/Virology
	Hexythiazox 是一种螨类生长调节剂和噻唑烷类杀螨剂，对多种螨类具有长效杀虫作用，适用于植物从萌芽到结果的任何生长阶段。
T30026	Amorphigenin	Others	Others
	Amorphigenin, a rotenoid compound, exhibits a strong larvicidal activity.
T63474	RyRs activator 1	Others	Others
	RyRs activator 1 是兰尼碱受体 (RyRs) 的有效激活剂。RyRs activator 1 在 0.5 mg/L 时，杀幼虫活性为100%，在 0.01 mg/L 时，杀幼虫活性为90%。
T81237	RyRs activator 4	Others	Others
	RyRs activator 4为一款昆虫兰尼碱受体激活剂，对粘虫幼虫显示出显著的杀灭活性，其半致死浓度(LC50)为1.32 mg/L。
T82355	GABA-IN-2	Others	Others
	GABA-IN-2 (Compound 5) 为GABA抑制剂，展现出杀幼虫效果和显著的杀虫能力，在浓度50 mg/L下的死亡率达到87%。
T82356	GABA-IN-1	Others	Others
	GABA-IN-1 (Compound 6)为GABA抑制剂，具备显著的杀幼虫效能与杀虫功能，在浓度为50 mg/L时，致死率达93%。
T63672	RyRs activator 2	Others	Others
	RyRs activator 2 是兰尼碱受体 (RyRs) 的有效激活剂。RyRs activator 2 的杀幼虫活性为 30%，与氯虫苯甲酰胺 (30%) 相当，优于氰虫苯甲酰胺 (10%)。
T36541	Nornidulin	Others	Others
	Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 2 μg/ml) and has larvicidal activity toward Artemia (LC50 = 1.7 μg/ml). Nornidulin has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >116.4 μM).
T37560	Nidulin	Others	Others
	Nidulin is a depsidone originally isolated from A. nidulans. It is active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 4 μg/ml) and has larvicidal activity toward Artemia (LC50 = 2.8 μg/ml). Nidulin is cytotoxic to MOLT-3 cells (IC50 = 21.2 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >112.7 μM). It inhibits aromatase with an IC50 value of 11.2 μM.

化合物

Cat.No: T2180

Target: Parasite

Cat.No: T30026

Target: Others

RyRs activator 1

Cat.No: T63474

Target: Others

RyRs activator 4

Cat.No: T81237

Target: Others

Cat.No: T82355

Target: Others

Cat.No: T82356

Target: Others

RyRs activator 2

Cat.No: T63672

Target: Others

Cat.No: T36541

Target: Others

Cat.No: T37560

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6S0214	dl-Maackiain (+)-Maackiain,高丽槐素,Demethylpterocarpin	Apoptosis; Parasite	Apoptosis; Microbiology/Virology
	dl-Maackiain (Demethylpterocarpin) 是分离自Maackia amurensis Rupr.et Maxim 的一种杀幼虫剂，针对埃及伊蚊，其LD50为 21.95 μg/ ml。
T3S2072	3-Butylidenephthalide Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯	Parasite; Glucosidase	Metabolism; Microbiology/Virology
	3-Butylidenephthalide (Butylidene phthalide) 是从 Ligusticum chuanxiongHort 鉴定出的一种邻苯二甲酸酐衍生物，有杀虫活性。
TN2261	Tectoquinone	Others	Others
	Tectoquinone 具有很强的杀蚊幼虫活性。
T5795	Suberosin 软木花椒素	Others; NF-κB	NF-κB; Others
	Suberosin 可分离自Plumbago zeylanica 中，通过调节NF-AT 和NF-κB，抑制PHA-诱导的 PBMC 细胞增殖并捕获细胞周期G1过渡到 S 期，具有抗炎和抗血凝的活性。
T6S0071	Fraxinellone	HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
	Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。
TN3374	Alepterolic acid	Others	Others
	Alepterolic acid exhibits larvicidal properties against Aedes aegypti (L.) (Diptera, Culicidae), with LC50 of 87.3 ppm.
TN3151	6-Acetonyl-N-methyl-dihydrodecarine	Antifection	Microbiology/Virology
	6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.
TN1172	1-Hydroxy-2-methylanthraquinone	Others	Others
	1-Hydroxy-2-methylanthraquinone exhibits promising larvicidal activity.
T27834	Limonin glucoside CCRIS-6986,CCRIS 6986,CCRIS6986	Others	Others
	Limonin glucoside is a natural product in citrus fruits. It inhibits expression of HIV-1 and HTLV-1 in infected cells, induces apoptosis in colon adenocarcinoma cells, and exhibits larvicidal activity against species of Aedes.
TN4742	Patulitrin	Antifection	Microbiology/Virology
	Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.
T60859	5-Pentadecylresorcinol	Others	Others
	5-Pentadecylresorcinol (Adipostatin A) 对埃及伊蚊具有良好的杀幼虫活性，它是甘油3-磷酸脱氢酶 (GPDH) 抑制剂，IC50值为 4.1 μM。
TN1638	Evodol	Others	Others
	Evodol may as an anti-inflammatory agent or lead compound, it shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoe
TN3549	Burchellin	Antifection	Microbiology/Virology
	Burchellin has larvicidal activity, it can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3) at concentrations ¥ 30 ppm. Burchellin and licarin A have activity against Trypanosoma cruzi

天然产物

Cat.No: T6S0214

Synonym: (+)-Maackiain,高丽槐素,Demethylpterocarpin

Target: Apoptosis, Parasite

3-Butylidenephthalide

Cat.No: T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide,丁烯基苯酞,丁烯基苯酞；丁烯基酞内酯

Target: Parasite, Glucosidase

Cat.No: TN2261

Target: Others

Cat.No: T5795

Synonym: 软木花椒素

Target: Others, NF-κB

Cat.No: T6S0071

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Alepterolic acid

Cat.No: TN3374

Target: Others

6-Acetonyl-N-methyl-dihydrodecarine

Cat.No: TN3151

Target: Antifection

1-Hydroxy-2-methylanthraquinone

Cat.No: TN1172

Target: Others

Limonin glucoside

Cat.No: T27834

Synonym: CCRIS-6986,CCRIS 6986,CCRIS6986

Target: Others

Cat.No: TN4742

Target: Antifection

5-Pentadecylresorcinol

Cat.No: T60859

Target: Others

Cat.No: TN1638

Target: Others

Cat.No: TN3549

Target: Antifection

Cat. No.	Product Name	Target	Signaling Pathways
T70186	Methazolamide-d6
	Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...

同位素标记化合物

Methazolamide-d6

Cat.No: T70186

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