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Targets Recommended: COX

抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0435	Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925	COX	Immunology/Inflammation; Neuroscience
	Sulfinpyrazone (NSC-75925) 是一种口服有效的尿酸剂，具有抗血栓和血小板抑制作用。它可作用于慢性和间歇性痛风性关节炎。
T4509	Inositol nicotinate Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate	Others	Others
	Inositol nicotinate (Mesotal) 是一种血管扩张剂，可用于研究外周动脉疾病。
T1182	Levocarnitine propionate hydrochloride Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Levocarnitine propionate hydrochloride (ST-261) 可用于肾功能恶化，充血性心脏衰竭，间歇性跛行等疾病的研究。
T21460	Teriparatide acetate hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽	Others	Others
	Teriparatide acetate (Forteo) 是一种 PHT 激动剂，在 HEK293 细胞中的 IC50 为 2 nM。Teriparatide acetate 是一种重组形式的甲状旁腺激素。它是一种有效的合成代谢（即骨骼生长）剂，用于治疗某些形式的骨质疏松症。间歇使用特立帕肽比破骨细胞更能激活成骨细胞，从而导致骨骼整体增加。
T28296	Parogrelil hydrochloride INDI-702,NM-702,NT-702,NM702,INDI702	Others	Others
	Parogrelil is a phosphodiesterase (PDE3/PDE5A) inhibitor potentially for the treatment of intermittent. Parogrelil suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. Parogrelil improves reduced walking
T39123	Givosiran ALN-AS1,Givosiran	Others	Others
	Givosiran (ALN-AS1) is a small interfering RNA (siRNA) compound that specifically targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA (mRNA) to downregulate its expression. By doing so, Givosiran effectively inhibits the accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. This compound holds significant potential for further research on acute intermittent porphyria.
T36827	Acetoacetyl Coenzyme A (sodium salt hydrate) Acetoacetyl-CoA	Others	Others
	Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis.[3],[4] Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.[5]
T35445	1-Stearoyl-3-Oleoyl-rac-glycerol	Others	Others
	1-Stearoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains stearic acid at the sn-1 position and oleic acid at the sn-3 position. Intermittent fasting decreases skeletal muscle and hepatic levels of 1-stearoyl-3-oleoyl-rac-glycerol in New Zealand obese (NZO) mice.1 The concentration of 1-stearoyl-3-oleoyl-rac-glycerol decreases from 4.59 to 1.88% during the dry-curing process of Iberian ham.2References1. Baumeier, C., Kaiser, D., Heeren, J., et al. Caloric restriction and intermittent fa...

化合物

Sulfinpyrazone

Cat.No: T0435

Synonym: (+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925

Target: COX

Inositol nicotinate

Cat.No: T4509

Synonym: Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate

Target: Others

Levocarnitine propionate hydrochloride

Cat.No: T1182

Synonym: Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐

Target: Histamine Receptor

Teriparatide acetate

Cat.No: T21460

Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽

Target: Others

Parogrelil hydrochloride

Cat.No: T28296

Synonym: INDI-702,NM-702,NT-702,NM702,INDI702

Target: Others

Givosiran

Cat.No: T39123

Synonym: ALN-AS1,Givosiran

Target: Others

Acetoacetyl Coenzyme A (sodium salt hydrate)

Cat.No: T36827

Synonym: Acetoacetyl-CoA

Target: Others

1-Stearoyl-3-Oleoyl-rac-glycerol

Cat.No: T35445

Synonym:

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0070	Pentoxifylline Oxpentifylline,PTX,己酮可可碱,BL-191	HIV Protease; PDE; Adenosine Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂，具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。

天然产物

Pentoxifylline

Cat.No: T0070

Synonym: Oxpentifylline,PTX,己酮可可碱,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00806	HMBS Protein, Human, Recombinant (His) Pre-Uroporphyrinogen Synthase,PBG-D,Hydroxymethylbilane Synt...	Human	HEK293 Cells
	Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including...

重组蛋白

HMBS Protein, Human, Recombinant (His)

Cat.No: TMPJ-00806

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T71300	Pentoxifylline-d6
	Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 µM. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/...

同位素标记化合物

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抑制剂 & 化合物

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天然产物

重组蛋白

同位素标记化合物